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Angiopoietin-like protein 4 (ANGPTL4) is a potential circulating mediator connecting nutritional factors and fat metabolism, however, information is lacking on the exact role of ANGPTL4 on triglyceride metabolism in the thigh muscles and livers of ...
Xu Zhao, Huashan Huang
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Method for decreasing blood glucose and improving glucose tolerance using angiopoietin-like protein 4 [PDF]
Angiopoietin like protein 4 is a novel circulating protein predominantly expressed in adipose tissue and liver. Several recent studies demonstrated that angiopoietin like protein 4 is the target gene of peroxisome proliferation activators, the agonists ...
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Angiopoietin-like protein and lipid metabolism
Lipoprotein lipase, hepatic lipase, and endothelial lipase play a pivotal role in the clearance and remodelling of plasma lipoproteins. Their activity is governed at the level of gene transcription as well as via changes in enzyme activity by specific ...
Kersten, A.H.
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Item does not contain fulltextThe angiopoietin-like protein 4 (angptl4, also known as peroxisome proliferator-activated receptor [PPAR]gamma-induced angiopoietin-related protein) is a multifunctional protein associated with acute-phase response.
Marcondes, A.M. +9 more
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Inflammation increases plasma angiopoietin-like protein 4 in patients with the metabolic syndrome and type 2 diabetes [PDF]
Contains fulltext : 138901.pdf (Publisher’s version ) (Open Access)BACKGROUND: Angiopoietin-like protein 4 (ANGPTL4) inhibits lipoprotein lipase and associates with dyslipidemia.
Rensen, P.C. +8 more
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Angiopoietin-like 4: a decade of research
The past decade has seen a rapid development and increasing recognition of ANGPTL4 (angiopoietin-like 4) as a remarkably multifaceted protein that is involved in many metabolic and non-metabolic conditions. ANGPTL4 has been recognised as a central player
Tan, N.S. +4 more
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High Concentrations of Angiopoietin-Like Protein 4 Detected in Serum from Patients with Rheumatoid Arthritis Can Be Explained by Non-Specific Antibody Reactivity. [PDF]
Angiopoietin-like protein 4 (ANGPTL4) is suggested to be a master regulator of plasma triglyceride metabolism. Our aim was to study whether the previously reported high levels of ANGPTL4 detected in serum from patients with rheumatoid arthritis (RA) by ...
Elena Makoveichuk +4 more
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Patients with metastatic cancers often displayed multidrug resistance (MDR) and emerging studies have shown that the Angiopoietin-like 4 (ANGPTL4) protein plays critical roles in metastatic dissemination of cancer cells during epithelial-mesenchymal ...
Lim, Maegan Miang Kee
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Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover [PDF]
Angiopoietin-like 4 (ANGPTL4) is a secreted signaling protein that is implicated in cardiovascular disease, metabolic disorder, and cancer. Outside of its role in lipid metabolism, ANGPTL4 signaling remains poorly understood. Here, we identify ANGPTL4 as
Colozza, Gabriele +26 more
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Background Angiopoietin-like protein 4 (ANGPTL4) is recognized as a crucial regulator in lipid metabolism. Acetyl-CoA carboxylases (ACACAs) play a role in the β-oxidation of fatty acids.
Xinyi Li +11 more
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