Results 11 to 20 of about 97,507,719 (246)

Normalization of the serum angiopoietin-1 to angiopoietin-2 ratio reflects response in refractory/resistant multiple myeloma patients treated with bortezomib

open access: yesHaematologica, 2008
Neoangiogenesis is involved in the pathophysiology of multiple myeloma and angiopoietins possibly contribute to myeloma-induced neovascularization. Bortezomib’s antineoplastic potential includes an anti-angiogenic effect.
Konstantinos Anargyrou   +15 more
doaj   +3 more sources

Angiopoietin-2 is associated with albuminuria and microinflammation in chronic kidney disease. [PDF]

open access: yesPLoS ONE, 2013
Although cardiovascular disease (CVD) is the leading cause of mortality in patients with chronic kidney disease (CKD), the pathophysiology is not thoroughly understood. Given that elevated albuminuria or circulating angiopoietin-2 associates with CVD and
Fan-Chi Chang   +7 more
doaj   +3 more sources

Reduced angiopoietin-2 as a predictive biomarker for clomiphene citrate resistance in polycystic ovary syndrome

open access: yesJournal of Human Reproductive Sciences, 2021
Background: Even though angiopoeitin-2 and interleukin (IL)-23 are known to be altered in polycystic ovary syndrome (PCOS), their association with clomiphene citrate (CC) resistance has not been studied. Aim: The objective of the study was to investigate
Luxmipratha Rajendiran   +2 more
doaj   +2 more sources

Angiopoietin-2 and angiopoietin-2/angiopoietin-1 ratio as indicators of potential severity of Plasmodium vivax malaria in patients with thrombocytopenia. [PDF]

open access: yesPLoS ONE, 2014
Angiogenic factors such as angiopoietin 1 (Ang-1) and angiopoietin 2 (Ang-2) are biomarkers produced during activation and dysfunction of the vascular endothelium in several infectious diseases.
Luciano Teixeira Gomes   +5 more
doaj   +4 more sources

Advanced Glycation End-Products and Hyperglycemia Increase Angiopoietin-2 Production by Impairing Angiopoietin-1-Tie-2 System

open access: yesJournal of Diabetes Research, 2019
The angiopoietin-Tie-2 system plays a crucial role in the maintenance of endothelial integrity. Hyperglycemia and advanced glycation end-products (AGEs) are involved in endothelial cell dysfunction responsible of the pathogenesis of microvascular ...
Alessandra Puddu   +6 more
doaj   +3 more sources

Assessment of peripheral blood concentration of angiopoietin 1, angiopoietin 2 and Tie-2 (a tyrosine kinase receptor) of patients with goitre treated surgically

open access: yesVideosurgery and Other Miniinvasive Techniques, 2011
Introduction: Blood vessel formation by angiogenesis is essential for goitre development. Angiopoietin 1 (Ang-1),angiopoietin 2 (Ang-2) and Tie-2 receptor (rTie-2) are involved in part of angiogenesis.
Joanna Kalupa   +2 more
doaj   +1 more source

Endothelial Permeability and the Angiopoietin/Tie2 System Following Mild and Severe COVID-19

open access: yesArtery Research, 2023
Endotheliopathy plays a role in the development of acute kidney and lung injury in COVID-19, probably due to inflammation, endothelial permeability, vascular leakage and edema formation. This study examined alterations in the circulation of patients with
Carolien Volleman   +4 more
doaj   +2 more sources

Cooperation of Angiopoietin-2 and Angiopoietin-4 in Schlemm's Canal Maintenance

open access: yesInvestigative Opthalmology & Visual Science, 2022
Defects in the iridocorneal angle tissues, including the trabecular meshwork (TM) and Schlemm's canal (SC), impair aqueous humor flow and increase the intraocular pressure (IOP), eventually resulting in glaucoma. Activation of endothelial tyrosine kinase receptor Tie2 by angiopoietin-1 (Angpt1) has been demonstrated to be essential for SC formation ...
Kapiainen, E. (Emmi)   +4 more
openaire   +3 more sources

Angiopoietin-1/Angiopoietin-2 Ratio for Prediction of Preeclampsia [PDF]

open access: yesAmerican Journal of Hypertension, 2009
A number of different biophysical and biochemical markers have been proposed as predictors of preeclampsia. Factors involved in the angiogenic balance are suggested as candidate markers. The purpose of this prospective, longitudinal cohort study was to determine whether a ratio between Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) can be used to ...
Marie, Bolin   +6 more
openaire   +2 more sources

Serum Angiopoietin-1/Angiopoietin-2 at 16-18 Weeks of Gestation to Predict Preeclampsia [PDF]

open access: yes, 2021
Objective: To determine whether serum angiopoietin-1/angiopoietin-2 ratio can predict preeclampsia in women at 16–18 weeks of gestation, or not. Material and Methods: This was a prospective observational study that was conducted in pregnant women with ...
Ruangsak Lertkhachonsuk   +2 more
core   +1 more source

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