Future Science OA, 2022 Aim: The current study investigated the plasma levels of angiopoietin-1/-2 and their association with clinical outcomes of sepsis. Methods: Angiopoietin-1 and -2 levels were quantified in plasma from 105 patients with severe sepsis by ELISA.
Hoang Van Tong +2 more
exaly +4 more sources
Increased Expression of Angiopoietin 2 and Tie2 in Rosacea [PDF]
DermatopathologyIn this study we evaluated the expression of Angiopoietin 1, Angiopoietin 2, and Tie2 by immunohistochemistry in the skin of 10 patients with erythemato telangiectatic and papulopustular rosacea.
Aysin Kaya +3 more
doaj +5 more sources
Exploring Angiopoietin-2: Clinical Insights and Experimental Perspectives in Kidney Diseases [PDF]
Kidney International ReportsAngiopoietin-2, an important contributor to angiogenesis and vascular remodeling, is increasingly recognized in kidney research. This review explores clinical insights and experimental perspectives on angiopoietin-2 in kidney diseases. Traditionally seen
An-Jie Luo +2 more
doaj +3 more sources
Angiopoietin‐1, Angiopoietin‐2 and Vascular Endothelial Growth Factor Levels in Canine Leishmaniosis [PDF]
Veterinary Medicine and ScienceBackground Canine leishmaniosis (CanL) is a zoonotic vector–borne disease and is primarily associated with systemic inflammation, endothelial dysfunction and immune dysregulation. Although angiopoietins (Ang) and vascular endothelial growth factor (VEGF)
Gamze Gultekin +10 more
doaj +2 more sources
MicroRNA Profiles Targeting Angiopoietin-1, Angiopoietin-2, and TEK Receptor Tyrosine Kinase-2 Genes Associated with Angiogenesis in Proliferative Diabetic Retinopathy [PDF]
Türk Oftalmoloji DergisiObjectives: This study aims to assess the concentrations of angiopoietin-1, angiopoietin-2, and Tie-2, which are implicated in the pathophysiology of proliferative diabetic retinopathy (PDR), in the vitreous fluid and to evaluate the expression profiles ...
Hilal Sancar +3 more
doaj +2 more sources
Cathepsin K cleavage of angiopoietin-2 creates detrimental Tie2 antagonist fragments in sepsis [PDF]
The Journal of Clinical InvestigationElevated angiopoietin-2 is associated with diverse inflammatory conditions, including sepsis, a leading global cause of mortality. During inflammation, angiopoietin-2 antagonizes the endothelium-enriched receptor Tie2 to destabilize the vasculature.
Takashi Suzuki +13 more
doaj +2 more sources
Angiopoietin‐2 associates with poor prognosis in Moyamoya angiopathy [PDF]
Annals of Clinical and Translational NeurologyObjective Moyamoya angiopathy (MA) is a rare cerebrovascular disorder characterized by recurrent ischemic/hemorrhagic strokes due to progressive occlusion of the intracranial carotid arteries.
Gemma Gorla +10 more
doaj +2 more sources
Update Overview of the Role of Angiopoietins in Lung Cancer
Medicina, 2021 Angiogenesis is a biological process that involves the formation of new blood vessels from the existing vasculature, and it plays a fundamental role in the development and progression of several types of cancer, including lung cancer.
Dimitris Tsakogiannis +7 more
doaj +1 more source
Biomedicines, 2022 Hypercoagulation and endothelial dysfunction play central roles in severe forms of COVID-19 infections, but the molecular mechanisms involved are unclear.
Michael Hultström +9 more
doaj +1 more source
Effects of laser photocoagulation on serum angiopoietin-1, angiopoietin-2, angiopoietin-1/angiopoietin-2 ratio, and soluble angiopoietin receptor Tie-2 levels in type 2 diabetic patients with proliferative diabetic retinopathy [PDF]
International Journal of Ophthalmology, 2014 AIM: To determine the effects of laser photocoagulation on serum levels of angiopoietin-1 (Ang-1), angiopoietin-2 (Ang-2), soluble angiopoietin receptor Tie-2 (Tie-2), Ang-1/Ang-2 ratio and vascular endothelial growth factor (VEGF) in patients with type ...
Qiao-Ying You +3 more
doaj +1 more source