Results 21 to 30 of about 97,507,719 (246)

Angpt2/Tie2 autostimulatory loop controls tumorigenesis

EMBO Molecular Medicine, 2022
Invasive nonfunctioning (NF) pituitary neuroendocrine tumors (PitNETs) are non‐resectable neoplasms associated with frequent relapses and significant comorbidities.
Ninelia Minaskan Karabid, Tobias Wiedemann, Sebastian Gulde, Hermine Mohr, Renu Chandra Segaran, Julia Geppert, Maria Rohm, Giovanni Vitale, Germano Gaudenzi, Alessandra Dicitore, Donna Pauler Ankerst, Yiyao Chen, Rickmer Braren, Georg Kaissis, Franz Schilling, Mathias Schillmaier, Graeme Eisenhofer, Stephan Herzig, Federico Roncaroli, Jürgen B Honegger, Natalia S Pellegata   +20 more
doaj   +1 more source

Concentrated Secretome of Adipose Stromal Cells Limits Influenza A Virus-Induced Lung Injury in Mice

Cells, 2021
Despite vaccination and antivirals, influenza remains a communicable disease of high burden, with limited therapeutic options available to patients that develop complications.
Natalia V. Bogatcheva, Michael E. Coleman   +1 more
doaj   +1 more source

Angiopoietin-2 in experimental colitis [PDF]

Inflammatory Bowel Diseases, 2010
The pathophysiology of inflammatory bowel disease (IBD) includes leukocyte infiltration, blood and lymphatic remodeling, weight loss and protein enteropathy. The roles of angiopoietin-2 (Ang-2) in initiating gut inflammation, leukocyte infiltration and angiogenesis are not well understood.Disease activity index, histopathological scoring ...
Vijay C, Ganta, Walter, Cromer, Ginny L, Mills, James, Traylor, Merilyn, Jennings, Sarah, Daley, Benjamin, Clark, J Michael, Mathis, Michael, Bernas, Moheb, Boktor, Paul, Jordan, Marlys, Witte, J Steven, Alexander   +12 more
openaire   +2 more sources

Angiopoietins modulate endothelial adaptation, glomerular and podocyte hypertrophy after uninephrectomy. [PDF]

PLoS ONE, 2013
Glomerular capillary remodeling is an essential process in the development of glomerular hypertrophy. Angiopoietins, which are important regulators in angiogenesis, plays a role in the development of glomerulus during embryogenesis.
Wen Chih Chiang, Chun Fu Lai, Chi Ting Su, Wei Hao Peng, Ching Fang Wu, Fan Chi Chang, Yi Ting Chen, Shuei Liong Lin, Yung Ming Chen, Kwan Dun Wu, Kuo Shyan Lu, Tun Jun Tsai   +11 more
doaj   +1 more source

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source

Asessment Of Serum Angiopoietin_2 Level In Patients With Psoriasis Vulgaris [PDF]

Zagazig University Medical Journal, 2022
Background: psoriasis is a chronic inflammatory hyper proliferative skin disease. Angiogenesis play an important role in Psoriasis pathogenesis, occurring even before plaque formation.
Abd allah Esawy, Nermin Abd elfatth, Abd allah Kandil, Shimaa Azooz   +3 more
doaj   +1 more source

Angiopoietin 2 alters pancreatic vascularization in diabetic conditions. [PDF]

PLoS ONE, 2012
AIMS/HYPOTHESIS: Islet vascularization, by controlling beta-cell mass expansion in response to increased insulin demand, is implicated in the progression to glucose intolerance and type 2 diabetes. We investigated how hyperglycaemia impairs expansion and
Sophie Calderari, Cécile Chougnet, Maud Clemessy, Hervé Kempf, Pierre Corvol, Etienne Larger   +5 more
doaj   +1 more source

The Complex Role of Angiopoietin-2 in the Angiopoietin-Tie Signaling Pathway [PDF]

Cold Spring Harbor Perspectives in Medicine, 2012
The angiopoietin-Tie signaling system is a vascular-specific receptor tyrosine kinase pathway that is essential for normal vascular development. Although the basic functioning of the pathway is understood, many uncertainties remain about the role of certain members of the pathway, particularly angiopoietin-2 (Ang2), in pathological vascular remodeling ...
Gavin, Thurston, Christopher, Daly
openaire   +2 more sources

Whole blood angiopoietin-1 and -2 levels discriminate cerebral and severe (non-cerebral) malaria from uncomplicated malaria [PDF]

, 2009
Background Severe and cerebral malaria are associated with endothelial activation. Angiopoietin-1 (ANG-1) and angiopoietin-2 (ANG-2) are major regulators of endothelial activation and integrity.
Liles W Conrad, Kain, Kevin C, Kevin C Kain, Kain Kevin C, Liles, W C, Conroy, Andrea L, Conroy Andrea L, Krudsood Srivicha, Erin I Lafferty, Srivicha Krudsood, Lafferty Erin I, Lovegrove, Fiona E, Lafferty, Erin I, Tangpukdee, Noppadon, Fiona E Lovegrove, W Conrad Liles, Tangpukdee Noppadon, Lovegrove Fiona E, Krudsood, Srivicha, Liles, W Conrad, Andrea L Conroy, Noppadon Tangpukdee   +21 more
core   +1 more source

Correction: Angiopoietin-2 and Angiopoietin-2/Angiopoietin-1 Ratio as Indicators of Potential Severity of Plasmodium vivax Malaria in Patients with Thrombocytopenia. [PDF]

PLoS ONE, 2015
PLOS ONE Staff
doaj   +3 more sources