Results 191 to 200 of about 206,964 (305)

Yeast Display Technology Enables Rapid Discovery of Low-Nanomolar Macrocyclic Peptide Inhibitors of Human Angiotensin-Converting Enzyme 2. [PDF]

J Med Chem
Romanyuk Z, Bettin G, Brear P, Linciano S, Mazzocato Y, Bonadies S, Zanotto I, Mazzucco C, Monferone A, Soler MA, Pasut G, Martin S, Scarso A, Heinis C, Rothenberger S, Hyvönen M, Angelini A.   +16 more
europepmc   +1 more source

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

Journal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li, Chunguang Guo, Mingyao Luo, Chang Shu   +3 more
wiley   +1 more source

Circulating angiotensin-converting enzyme 2 concentration is associated with acute kidney injury and mortality in sepsis. [PDF]

PLoS One
Chen CE, Chou RH, Guo JY, Lu YW, Chang CC, Wu CH, Huang PH.   +6 more
europepmc   +1 more source

Myocardial Angiotensin-Converting Enzyme 2 Protein Expression in Ischemic Heart Failure. [PDF]

Int J Mol Sci, 2023
Siratavičiūtė V, Pangonytė D, Utkienė L, Jusienė L, Marcinkevičienė J, Stanionienė Z, Radikė R.   +6 more
europepmc   +1 more source

Prenatal exposure to antihypertensive medication: A systematic review of neurodevelopmental and educational outcomes

JCPP Advances, EarlyView.
This systematic review investigated the association of prenatal exposure to antihypertensive medication with longer‐term poor neurodevelopmental outcomes by evaluating the findings from existing literature. We undertook a systematic review of previous studies looking specifically at neurodevelopmental outcomes in children.
Shrifah Alkhalaf, Sarjit Singh, Jill P. Pell, Scott M. Nelson, Daniel F. Mackay, Michael Fleming   +5 more
wiley   +1 more source

Angiotensin‑converting enzyme 2 expression in human tumors: Implications for prognosis and therapy (Review). [PDF]

Oncol Rep
Rizopoulos T, Assimakopoulou M.
europepmc   +1 more source

Effects of spike proteins on angiotensin converting enzyme 2 (ACE2). [PDF]

Arch Biochem Biophys, 2023
Bejoy J, Williams CI, Cole HJ, Manzoor S, Davoodi P, Battaile JI, Kaushik A, Nikolaienko SI, Brelidze TI, Gychka SG, Suzuki YJ.   +10 more
europepmc   +1 more source

Quality of hospital medicine care in Veterans Affairs hospitals versus non‐Veterans Affairs hospitals: A systematic review of comparative studies

Journal of Hospital Medicine, EarlyView.
Abstract Background The Veterans Health Administration (VA) cares for more than one million hospitalized Veterans each year. There is limited knowledge on how hospital medicine care in VA facilities compares with non‐VA hospitals in terms of the Institute of Medicine domains of healthcare access, patient experience, quality, clinical outcomes, and cost.
Paul G. Shekelle, Robert E. Burke, Eric A. Apaydin, Meron M. Begashaw, Charlie M. Wray   +4 more
wiley   +1 more source

Retraction Note: Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis prevents lipopolysaccharide-induced apoptosis of pulmonary microvascular endothelial cells by inhibiting JNK/NF-κB pathways. [PDF]

Sci Rep
Li Y, Cao Y, Zeng Z, Liang M, Xue Y, Xi C, Zhou M, Jiang W.   +7 more
europepmc   +1 more source

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen, Didem Şöhretoğlu, Ayşe Kuruüzüm‐Uz   +2 more
wiley   +1 more source