Кардиоваскулярная терапия и профилактика, 2020 The COVID-19 pandemic is a serious threat to global health. The infection mechanism is the binding of SARS-CoV-2 to angiotensin-converting enzyme 2 (ACE2) and internalization of the complex by the host cell.
O. M. Drapkina, L. E. Vasilyeva
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Spike protein of the SARS-CoV-2 virus and its relationship with the angiotensin-converting enzyme-2
Revista Información Científica, 2021 Introduction: COVID-19 caused by the SARS-CoV-2 virus is a pandemic that has claimed the lives of millions of people and overloaded health services around the world.
María Teresa Díaz-Armas +3 more
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Frontiers in Medicine, 2020 Angiotensin-converting enzyme 2 (ACE2) is the receptor for COVID-19 (SARs-CoV-2). ACE2 protects the lung and heart from acute respiratory distress syndrome (ARDS) and acute myocarditis and arrhythmias, because it breaks down Angiotensin II, which has ...
Eugenie R. Lumbers +9 more
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Attenuation of Focal Cerebral Ischemic Injury Following Post Ischemic Inhibition of Angiotensin Converting Enzyme (ACE) Activity in Normotensive Rat [PDF]
Central renin angiotensin system has an important role on the cerebral microcirculation and metabolism. Our previous work showed that inhibition of angiotensin converting enzyme (ACE) activity prior to induction of ischemia protected the brain from ...
دهقان, غلامعباس +1 more
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Angiotensin converting enzyme and vascular endothelial growth factor responses to exercise training in claudicants: the role of ace inhibition [PDF]
, 2009 Exercise training is well recognised as an effective treatment for intermittent claudication. The mechanism underlying exercise induced improvements is multi-factorial but remains poorly understood.
Ng, P.
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The dual endothelin converting enzyme/neutral endopeptidase inhibitor SLV-306 (daglutril), inhibits systemic conversion of big endothelin-1 in humans [PDF]
, 2012 Aims - Inhibition of neutral endopeptidases (NEP) results in a beneficial increase in plasma concentrations of natriuretic peptides such as ANP.
Johnston, F. +26 more
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Heterodimerization of apelin receptor and neurotensin receptor 1 induces phosphorylation of ERK1/2and cell proliferationviaGαq-mediated mechanism [PDF]
, 2014 Dimerization of G protein-coupled receptors (GPCRs) is crucial for receptor function including agonist affinity, efficacy, trafficking and specificity of signal transduction, including G protein coupling.
Cai, X +9 more
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Adenoviral delivery of angiotensin-(1-7) or angiotensin-(1-9) inhibits cardiomyocyte hypertrophy via the mas or angiotensin Type 2 receptor [PDF]
, 2012 The counter-regulatory axis of the renin angiotensin system peptide angiotensin-(1-7) [Ang-(1-7)] has been identified as a potential therapeutic target in cardiac remodelling, acting via the mas receptor.
Nicklin Stuart A. +11 more
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, 2014 Objective: To investigate the effect of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on pneumonia hospitalization in patients with stroke history in Taiwan. Methods: We conducted a case-crossover study using the National
Liu, Chia-Lin;Shau, Wen-Yi;Wu, Chi-Shin;Lai, Mei-Shu +1 more
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The Application of Clinical Genetics, 2019 Mohanad Yasir Al-Radeef,1 Hayder Adnan Fawzi,2 Ali Abdulmajid Allawi31Department of Clinical Pharmacy, College of Pharmacy, Tikrit University, Tikrit, Iraq; 2Department of Clinical Pharmacy, Baghdad Medical City Hospital, Baghdad, Iraq; 3Department of ...
Al-Radeef MY, Fawzi HA, Allawi AA
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