Results 241 to 250 of about 362,216 (339)
Abstract Aims Sodium–glucose co‐transporter‐2 (SGLT2) inhibitors improve health status and outcomes in the setting of heart failure (HF) across the range of ejection fraction (EF). Baseline kidney disease is common in HF, complicates HF management and is strongly linked to worse health status. This study aimed to assess whether the treatment effects of
Andrew P. Ambrosy+12 more
wiley +1 more source
Autophagy fine-tuning by angiotensin-(1-9) in cultured rat cardiomyocytes. [PDF]
Bustamante M+10 more
europepmc +1 more source
A Meta-Analysis of the Impact of Using Angiotensin-Converting Enzyme Inhibitors (ACEIs) or Angiotensin II Receptor Blockers (ARBs) on Mortality, Severity, and Healthcare Resource Utilization in Patients with COVID-19. [PDF]
Li R, Zhang J, Ren L.
europepmc +1 more source
Vericiguat improves cardiac remodelling and function in rats with doxorubicin‐induced cardiomyopathy
Abstract Purpose Vericiguat, a soluble guanylate cyclase (sGC) stimulator, has been demonstrated effective in improving prognosis of patients with heart failure with reduced ejection fraction. However, there are limited data concerning the effect of vericiguat in patients with doxorubicin (DOX)‐induced cardiomyopathy (DIC).
Wen Chen+6 more
wiley +1 more source
Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of pancreatic cancer: a mendelian randomization analysis. [PDF]
Yao Z+6 more
europepmc +1 more source
Abstract Aims Differences in guideline‐directed medical therapy (GDMT) and clinical outcomes have been observed between heart failure (HF) patients with atrial fibrillation (AF) versus those in sinus rhythm. This study evaluated the effects of up‐titration of HF therapies, consisting of beta‐blockers, angiotensin‐converting‐enzyme inhibitors (ACEis ...
Arietje J.L. Zandijk+6 more
wiley +1 more source
Angiotensin IV does not exert prothrombotic effects in vivo. [PDF]
Wu Q+5 more
europepmc +1 more source
Abstract Aims Cardiac resynchronization therapy (CRT) is guideline recommended for the treatment of symptomatic heart failure (HF) with reduced left ventricular ejection fraction and prolonged QRS. However, patients with common comorbidities, such as persistent/permanent atrial fibrillation (AF), are often under‐represented in clinical trials.
Ignacio García‐Bolao+17 more
wiley +1 more source