Results 251 to 260 of about 362,216 (339)

The ADESTE trial: A phase 2 study of enibarcimab, a monoclonal antibody targeting adrenomedullin, in acute heart failure

ESC Heart Failure, EarlyView.
Abstract Aims This study aimed to conduct a phase 2 proof‐of‐concept and safety study to evaluate the effect of ENIBARCIMAB (EN), a non‐neutralizing humanized monoclonal antibody targeting the N‐terminus of adrenomedullin (ADM), administered immediately after stabilization with standard of care (SoC) treatment, in patients hospitalized for acute heart ...
Anggoro Budi Hartopo, Arinal Chairul Achyar, Hendry Purnasidha Bagaswoto, Firandi Saputra, Hasanah Mumpuni, Dyah Adhi Kusumastuti, Teguh Triyono, Usi Sukorini, Metalia Puspitasari, Budi Yuli Setianto, Mohammad Saifur Rohman, Muhammad Anshory, Yoga Waranugraha, Putri Annisa Kamila, Agustin Iskandar, Hani Susianti, Andreas Bergman, Claudia Knothe, Paola Antonini, Salvatore Di Somma   +19 more
wiley   +1 more source

Guideline‐directed medical therapy rates in heart failure patients with reduced ejection fraction in a diverse cohort

ESC Heart Failure, EarlyView.
Abstract Aims Guideline‐directed medical therapy (GDMT) is recommended for all patients with heart failure with reduced ejection fraction (HFrEF). Despite this, little data exist describing GDMT use in diverse, real‐world populations including the use of vasodilators, prescribed primarily to Black populations.
Natalia C. Berry, Yi‐Shin Sheu, Karen Chesbrough, R. Clayton Bishop, Suma Vupputuri   +4 more
wiley   +1 more source

M-TEER During Pregnancy: A Lifeline for Mother and Child. [PDF]

JACC Case Rep
Patrascu A, Fam NP.
europepmc   +1 more source

Severity of tricuspid regurgitation predicts risk of recurrence of atrial fibrillation after pulmonary vein isolation

ESC Heart Failure, EarlyView.
Abstract Aims Tricuspid regurgitation (TR) results in right atrial remodelling, thus promoting the formation of a substrate for atrial fibrillation (AF). In turn, AF may cause TR by annulus dilatation. We investigated whether the presence of TR affects the efficacy of pulmonary vein isolation (PVI) for AF. Methods and results In patients undergoing PVI,
Jan Wintrich, Dimitrios Bismpos, Anika Teusch, Valerie Pavlicek, Patrick Fischer, Felix Mahfoud, Michael Böhm, Christian Ukena   +7 more
wiley   +1 more source

Predicting right ventricular failure after left ventricular assist device implant: A novel approach

ESC Heart Failure, EarlyView.
Abstract Aims Right ventricular (RV) failure (RVF) after left ventricular assist device (LVAD) implant is an important cause of morbidity and mortality. Modern, data‐driven approaches for defining and predicting RVF have been under‐utilized. Methods Two hundred thirty‐two patients were identified with a mean age of 55 years; 40 (17%) were women, 132 ...
Carissa E. Livingston, Dale Kim, Lacey Serletti, Andrea Jin, Sriram Rao, Michael V. Genuardi, Eliot G. Peyster   +6 more
wiley   +1 more source

Novel Versus Conventional Sequencing of β-Blockers, Sodium/Glucose Cotransportor 2 Inhibitors, Angiotensin Receptor-Neprilysin Inhibitors, and Mineralocorticoid Receptor Antagonists in Stable Patients With Heart Failure With Reduced Ejection Fraction (NovCon Sequencing Study): Protocol for a Randomized Controlled Trial.

JMIR Res Protoc
Karamchand S, Chipamaunga T, Naidoo P, Naidoo K, Rambiritch V, Ho K, Chilton R, McMahon K, Leisegang R, Weich H, Hassan K.   +10 more
europepmc   +1 more source

Hypothesis: Reactive increases in plasma renin activity attenuate the fall in blood pressure caused by salt depletion and renin-angiotensin system inhibition. [PDF]

J Hypertens
Sealey JE, Blumenfeld JD.
europepmc   +1 more source

Poor communication impairs optimal care of patients with heart failure and erectile dysfunction

ESC Heart Failure, EarlyView.
Abstract Aims Heart failure (HF) and erectile dysfunction (ED) share numerous risk factors and pathogenetic mechanisms, resulting in a high prevalence of ED among male patients with HF. This questionnaire‐based study aimed to better understand the patient's journey from a patient perspective and that of healthcare professionals (HCPs) regarding ...
Lea Leist, Lenka Hausmann, Carla Pohlink
wiley   +1 more source

Current Best Evidence for 5 Promising Medications Used for Scar Minimization Therapy. [PDF]

Plast Surg (Oakv)
Dua N, Burke E, Rasmussen J.
europepmc   +1 more source

Early genetic screening and cardiac intervention in patients with cardiomyopathies in a multidisciplinary clinic

ESC Heart Failure, EarlyView.
Abstract Aims Patients with cardiomyopathies are a heterogeneous group of patients who experience high morbidity and mortality. Early cardiac assessment and intervention with access to genetic counselling in a multidisciplinary Cardiomyopathy Clinic may improve outcomes and prevent progression to advanced heart failure.
Chandu Sadasivan, Luke R. Gagnon, Deepan Hazra, Kaiming Wang, Erik Youngson, Jissy Thomas, Anita Y.M. Chan, D. Ian Paterson, Finlay A. McAlister, Tara Dzwiniel, Wayne Tymchak, Susan Christian, Gavin Y. Oudit   +12 more
wiley   +1 more source