Results 261 to 270 of about 206,446 (295)

Radioimmunoassay of fowl angiotensin I

General and Comparative Endocrinology, 1981
Abstract Angiotensin I (ANG I) from various nonmammalian vertebrates does not bind the antibody to human ANG I, and thus radioimmunoassay (RIA) is not applicable for measurement of renin activity. It is largely due to this difficulty that biochemistry and physiology of the renin-angiotensin system of nonmammalian vertebrates have not been studied ...
H, Nishimura, M A, Madey, J N, Mugaas, M C, Khosla, J T, Crofton   +4 more
openaire   +2 more sources

Angiotensin receptors and angiotensin I-converting enzyme in rat intestine

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1989
The purpose of this study was to map the distribution of angiotensin II (ANG II) receptors and ANG I-converting enzyme (ACE) in rat intestine. ANG II binding sites were visualized by in vitro autoradiography using iodinated [Sar1, Ile8]ANG II. The distribution of ACE was mapped using an iodinated derivative of lisinopril. Male Sprague-Dawley rats were
K A, Duggan, F A, Mendelsohn, N R, Levens   +2 more
openaire   +2 more sources

I. Pharmacology of Angiotensin Antagonists

Canadian Journal of Physiology and Pharmacology, 1973
Several analogues of angiotensin II (ATII) have been characterized as antagonists against ATII and ATI, and compared with lidoflazine and guancydine, on the rat isolated stomach strip.The pA2 and pA10 values have been determined according to Schild (1947, Br. J. Pharmacol. 2, 189–206) after 5 and 15 min of contact of the antagonist with the tissue.The
D, Regoli, W K, Park, F, Rioux
openaire   +3 more sources

Intrarenal vascular effects of angiotensin I and angiotensin II

American Journal of Physiology-Heart and Circulatory Physiology, 1981
The effects of angiotensin I (250 pmol) and angiotensin II (7.5 pmol) on total renal blood flow and its cortical distribution were examined in 25 dogs anesthetized with pentobarbital. These peptides were administered as bolus injections directly into the left renal artery.
openaire   +2 more sources

Angiotensin I–Converting Enzyme Genotypes and Angiotensin II Receptors

Hypertension, 1996
In the present study, we studied angiotensin II type 1 (AT 1 ) and type 2 (AT 2 ) receptor messengers by quantitative reverse transcriptase–polymerase chain reaction. We examined peripheral blood mononuclear cells from 30 healthy subjects and 50 subjects with primary hypertension, in whom ...
J L, Dieguez-Lucena, P, Aranda-Lara, M, Ruiz-Galdón, J, García-Villanova, M, Morell-Ocaña, A, Reyes-Engel   +5 more
openaire   +2 more sources

Evidence that pepsitensin is angiotensin I

Experientia, 1973
L'angiotensine I et le Leu-Val-Tyr-Ser sont les principaux produits des hydrolyses peptiques du tetradecapeptide substrat de la renine, realises a pH 3 et a pH 6. Ces resultats indiquent qu'il n'y a qu'une seule pepsitensine laquelle est identique a l'angiotensine I.
A C, Paiva, A, Grandino
openaire   +2 more sources

Angiotensin-I-converting enzyme in germinomas

Human Pathology, 1988
Angiotensin-I-converting enzyme (ACE) was detected in 18 germinomas, both of testicular or extratesticular localization, and studied by immunohistochemical methods using specific polyclonal antibodies and by enzyme activity measurements. ACE was also detected in normal human germ cells. On the other hand, it was not present in other types of testicular
J P, Saint-Andre, F, Alhenc-Gelas, V, Rohmer, M F, Chretien, J C, Bigorgne, P, Corvol   +5 more
openaire   +2 more sources

Pulmonary activation of synthetic angiotensin I

Life Sciences, 1968
Abstract Angiotensin I was synthetized by the solid-phase method and tested in anesthetized rat, cat, rabbit and dog blood-pressure preparations. Removal from the circulation by systemic vascular beds averaged 67%. Pressor responses following intra-aortic injections were half as potent as those resulting from intra-jugular administration.
P, Biron, C G, Huggins
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Des-aspartate-angiotensin I, a novel angiotensin AT1 receptor drug

European Journal of Pharmacology, 2015
The review describes DAA-I (des-aspartate-angiotensin-I) as a prototype of a novel class of drugs that acts as agonists on the angiotensin AT1 receptor or ARAs (angiotensin receptor agonists). DAA-I is a component of the renin angiotensin system. Earlier studies showed that it was rapidly metabolized to angiotensin III.
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[Angiotensin-I converting enzyme].

Nihon rinsho. Japanese journal of clinical medicine, 1995
Angiotensin I-converting enzyme (ACE) converts the largely inactive decapeptide angiotensin I to the active octapeptide angiotensin II. ACE is a key component of the renin-angiotensin system that has long been suspected to play a role in the pathogenesis of hypertension and cardiovascular disease.
K, Nakai, T, Syoh, K, Hiramori
openaire   +1 more source