Results 271 to 280 of about 221,266 (311)

Intrarenal Formation of Angiotensin I

Science, 1971
In 5 patients and 16 dogs the mean concentration of angiotensin I, but not II, was higher in the plasma of the renal vein than in the plasma of the renal artery. The fact that I was higher in the vein than in the artery supports the concept that I is formed in the renal vasculature.
H D, Itskovitz, C, Odya
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Radioimmunoassay of fowl angiotensin I

General and Comparative Endocrinology, 1981
Abstract Angiotensin I (ANG I) from various nonmammalian vertebrates does not bind the antibody to human ANG I, and thus radioimmunoassay (RIA) is not applicable for measurement of renin activity. It is largely due to this difficulty that biochemistry and physiology of the renin-angiotensin system of nonmammalian vertebrates have not been studied ...
H, Nishimura, M A, Madey, J N, Mugaas, M C, Khosla, J T, Crofton   +4 more
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Evidence that pepsitensin is angiotensin I

Experientia, 1973
L'angiotensine I et le Leu-Val-Tyr-Ser sont les principaux produits des hydrolyses peptiques du tetradecapeptide substrat de la renine, realises a pH 3 et a pH 6. Ces resultats indiquent qu'il n'y a qu'une seule pepsitensine laquelle est identique a l'angiotensine I.
A C, Paiva, A, Grandino
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Angiotensin receptors and angiotensin I-converting enzyme in rat intestine

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1989
The purpose of this study was to map the distribution of angiotensin II (ANG II) receptors and ANG I-converting enzyme (ACE) in rat intestine. ANG II binding sites were visualized by in vitro autoradiography using iodinated [Sar1, Ile8]ANG II. The distribution of ACE was mapped using an iodinated derivative of lisinopril. Male Sprague-Dawley rats were
K A, Duggan, F A, Mendelsohn, N R, Levens   +2 more
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I. Pharmacology of Angiotensin Antagonists

Canadian Journal of Physiology and Pharmacology, 1973
Several analogues of angiotensin II (ATII) have been characterized as antagonists against ATII and ATI, and compared with lidoflazine and guancydine, on the rat isolated stomach strip.The pA2 and pA10 values have been determined according to Schild (1947, Br. J. Pharmacol. 2, 189–206) after 5 and 15 min of contact of the antagonist with the tissue.The
D, Regoli, W K, Park, F, Rioux
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Evidence for the Conversion of Angiotensin I to Angiotensin II by the Coronary Microcirculation

Blood Vessels, 2008
Cardiac tissue from hamster neonates was transplanted into the hamster cheek pouch. After vascularization of the transplanted tissue the vessels were tested for their ability to convert angiotensin I (A_I) to angiotensin II (A_II).
K G, Cornish, W L, Joyner, J P, Gilmore
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Effects of des-Asp-angiotensin I on the contractile action of angiotensin II and angiotensin III

European Journal of Pharmacology, 1995
Nanomolar concentrations of des-Asp-angiotensin I potentiated the contractile action of angiotensin II on the rabbit aortic ring but attenuated the contractile action of angiotensin III in the same tissue. Indomethacin had no effect on the potentiation of angiotensin II but inhibited the attenuation of angiotensin III.
Sim, M.K., Yuan, H.T.
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Angiotensin converting enzyme and the arrhythmogenic action of angiotensin I: cardiac cell membrane as a site of angiotensin I conversion

Regulatory Peptides, 2004
The influence of angiotensin I (Ang I) on heart excitability and refractoriness was investigated in isolated right ventricular muscle of adult rats as well as in isolated ventricular myocytes. The results indicated that Ang I (10(-8) M) added to the bath solution, decreased the action potential duration from 50.4 +/- 3.6 to 33.9 +/- 3.9 ms (P < 0.05 ...
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Iodination of Angiotensin I for Use in Radioimmunoassay

The Journal of Clinical Endocrinology & Metabolism, 1971
ABSTRACT The method of Haber for the purification of (125I)-labeled angiotensin by high volt age paper electrophoresis has been modified. Instead of eluting the labeled peptide from the paper in a single bulk elution, serial small elutions are collected, resulting in a highly purified product in later elutions.
R, Wilkinson, J A, Leutscher, G W, Nokes
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A novel sequence in kangaroo angiotensin I

Clinical and Experimental Pharmacology and Physiology, 1974
SUMMARY 1. The incubation of kangaroo renin-substrate with renin from kangaroo, hog or sheep yields angiotensin having pressor activity in the rat. 2. Kangaroo angiotensin I is not reactive in radioimmunoassay which is sensitive to other forms of angiotensin I. 3.
J B, Best, J R, Blair West, J P, Coghlan, E J, Cran, R T, Fernley, P A, Simpson   +5 more
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