Results 31 to 40 of about 354,411 (314)

Characterization of the intrarenal renin‐angiotensin system in cats with naturally occurring chronic kidney disease

Journal of Veterinary Internal Medicine, 2022
Background The role of the renin‐angiotensin‐aldosterone system in cats with chronic kidney disease (CKD) is incompletely understood. Objective To characterize components of the intrarenal renin‐angiotensin system (RAS) in cats with CKD.
Bianca N. Lourenço, Amanda E. Coleman, Roy D. Berghaus, Jaime L. Tarigo, Chad W. Schmiedt, Scott A. Brown   +5 more
doaj   +1 more source

Effects of the selective chymase inhibitor TEI‐F00806 on the intrarenal renin–angiotensin system in salt‐treated angiotensin I‐infused hypertensive mice

Experimental Physiology, 2018
New Findings What is the central question of this study? Can chymase inhibition prevent angiotensin I‐induced hypertension through inhibiting the conversion of angiotensin I to angiotensin II in the kidney?
Tuba M. Ansary, Maki Urushihara, Yoshihide Fujisawa, Sayaka Nagata, Hidenori Urata, Daisuke Nakano, Hitomi Hirofumi, Kazuo Kitamura, Shoji Kagami, Akira Nishiyama   +9 more
doaj   +1 more source

Ethanolic Extract of Salvia hispanica L. Regulates Blood Pressure by Modulating the Expression of Genes Involved in BP-Regulatory Pathways

Molecules, 2020
Hypertension (HT) is considered to be a potential risk factor for cardiovascular diseases and has been directly related to pathologies such as obesity and dyslipidemias.
Gerardo I. Arredondo-Mendoza, Zacarías Jiménez-Salas, Francisco Javier Guzmán-de la Garza, Elizabeth Solís-Pérez, Manuel López-Cabanillas-Lomelí, Blanca Edelia González-Martínez, Eduardo Campos-Góngora   +6 more
doaj   +1 more source

Role of protein kinase C in inhibition of renin release caused by vasoconstrictors [PDF]

, 1986
It was the aim of the present study to get insight into some of the intracellular mechanisms by which the vasoconstrictor hormones angiotensin II (ANG II), arginine vasopressin (AVP), and norepinephrine (NE) inhibit renin release from renal ...
Bauer, C., Bührle, C., Hackenthal, E., Hutter, A., Kurtz, Armin, Nobiling, R., Pfeilschifter, J., Taugner, R.   +7 more
core   +1 more source

Alterations in the Renin-Angiotensin System in Experimental Septic Shock

Critical Care Explorations
OBJECTIVES:. To analyze dynamic changes in the renin-angiotensin system (RAS) during septic shock, focusing on angiotensin-converting enzyme (ACE) activity and the balance between angiotensin peptides, using a mass spectrometry method.
Bruno Garcia, MD, PhD, Benoit Ter Schiphorst, MD, MSc, Fuhong Su, MD, PhD, Adrien Picod, MD, PhD, Theo Ikenna-Uba, PhD, Raphaël Favory, MD, PhD, Filippo Annoni, MD, Alexandre Mebazaa, MD, PhD, Jean-Louis Vincent, MD, PhD, Jacques Creteur, MD, PhD, Fabio S. Taccone, MD, PhD, Antoine Herpain, MD   +11 more
doaj   +1 more source

Captopril Enhances Cardiac Vagal but Not Sympathetic Neurotransmission in Pithed Rats

Journal of Pharmacological Sciences, 2004
The effect of captopril on neurally evoked bradycardia and tachycardia was investigated in pithed rats. Captopril enhanced the vagal nerve stimulation-evoked bradycardia.
Yoshinobu Takata, Takanori Arai, Shigeto Suzuki, Junichi Kurihara, Takashi Uezono, Yoko Okubo, Hitoshi Kato   +6 more
doaj   +1 more source

A novel mechanism of action for angiotensin-(1-7) via the angiotensin type 1 receptor [PDF]

, 2016
No abstract ...
Nicklin, Stuart A.
core   +1 more source

Classical and Alternative Pathways of the Renin–Angiotensin–Aldosterone System in Regulating Blood Pressure in Hypertension and Obese Adolescents

Biomedicines
Primary hypertension (PH) is the leading form of arterial hypertension (AH) in adolescents. Hypertension is most common in obese patients, where 20 to 40% of the population has elevated blood pressure.
Adrian Martyniak, Dorota Drożdż, Przemysław J. Tomasik   +2 more
doaj   +1 more source

Lack of direct evidence for a functional role of voltage-operated calcium channels in juxtaglomerular cells [PDF]

, 1990
In this study we have examined the role of voltage-gated calcium channels in the regulation of calcium in juxtaglomerular cells. Using a combination of patch-clamp and single-cell calcium measurement we obtained evidence neither for voltage-operated ...
Chegini, S., Kurtz, Armin, Penner, R., Skott, O.   +3 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source