Results 121 to 130 of about 4,889,938 (291)

Synergistic co‐operation of signal transducer and activator of transcription 5B with activator protein 1 in angiotensin II‐induced angiotensinogen gene activation in vascular smooth muscle cells [PDF]

, 2009
Mei Han, Aiying Li, Meng Fang, Li‐Hua Dong, Bin Zheng, Haijuan Hu, Lei Nie, Jin‐Kun Wen   +7 more
openalex   +1 more source

Intracellular Catalytic Photooxygenation of α‐Synuclein Amyloid

ChemistryEurope, EarlyView.
Amyloid‐selective catalytic photooxygenation reduces amyloid toxicity, aggregation tendencies, and seeding activities. Achieving therapeutic catalysis for intracellular amyloids is challenging due to conflicting oxygenation and reductive cellular environments.
Atsushi Iwai, Youhi Hwang, Hiroki Umeda, Taka Sawazaki, Ikumi Tomizawa, Maiko Ono, Makoto Higuchi, Youhei Sohma, Yukiko Hori, Taisuke Tomita, Harunobu Mitsunuma, Motomu Kanai   +11 more
wiley   +1 more source

Interactions between angiotensin II and arginine vasopressin in water homeostasis [PDF]

, 2009
Robert W. Schrier
openalex   +1 more source

Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives

ChemPlusChem, EarlyView.
Nitroso (hetero)aromatic compounds are bioactive molecules with antiviral, anticancer, neuroprotective, and antimicrobial properties. This review highlights their mechanisms of action—oxidative stress, DNA damage, and enzyme inhibition—alongside synthesis, structure–activity relationships, and toxicity challenges, offering insight into their ...
Silvia Roscales, Aurelio G. Csáky
wiley   +1 more source

A dilated cardiomyopathy mutation blunts adrenergic response and induces contractile dysfunction under chronic angiotensin II stress

, 2015
Ross Wilkinson, Weihua Song, Natalia Smoktunowicz, Steven B. Marston   +3 more
openalex   +2 more sources

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi‐Omics and Multi‐Modal Data Analysis

Clinical Pharmacology &Therapeutics, EarlyView.
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu, Hui Shen, Jonathan Greenbaum, Qiao‐Rong Yi, Shuang Liang, Yue Zhang, Jia‐Chen Liu, Chuan Qiu, Lan‐Juan Zhao, Qing Tian, Kuan‐Jui Su, Zhe Luo, Li Wu, Xiang‐He Meng, Hong‐Mei Xiao, Yun Deng, Yang Li, Dragana Lovre, Vivian Fonseca, Fernando L. Sanchez, Li‐Jun Tan, Hong‐Wen Deng   +21 more
wiley   +1 more source

A Case Report of Angiotensin II Use in the Treatment of Refractory Shock due to Amlodipine and Lisinopril Toxicity

Case Reports in Critical Care
Conclusion: Despite evidence of efficacy in refractory vasodilatory shock secondary to sepsis, there is a paucity of data on the use of angiotensin II as an adjunctive vasopressor in drug-induced shock.
John H. Keller, Kayla J. Kendric, Kathy T. LeSaint   +2 more
doaj   +1 more source

Beyond blood pressure: new roles for angiotensin II

, 1999
Ralph Lucius, S. Gallinat, Silke Busche, Philip Rosenstiel, Thomas Unger   +4 more
openalex   +2 more sources

Impact of Antihypertensive Treatment on Outcomes of Adjuvant Bevacizumab for Ovarian Cancer (IATRO), Results from a Nationwide Emulated Clinical Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Antiangiogenic therapy with bevacizumab improves outcomes in ovarian cancer but induces hypertension, leading to major adverse cardiovascular events (MACE). While calcium channel blockers (CCBs) and angiotensin‐converting enzyme inhibitors (ACEi) are recommended for managing bevacizumab‐associated hypertension, their impacts on cancer progression and ...
Floriane Jochum, Élise Dumas, Joe‐Elie Salem, Stéphane Ederhy, Anne‐Sophie Hamy, Lise Lecointre, Enora Laas, Fabien Reyal, Fabrice Lecuru, Cherif Akladios, Paul Gougis   +10 more
wiley   +1 more source

Hypertension, Small Arteries, and Pathways for Angiotensin II Generation [PDF]

, 2000
Norman K. Hollenberg
openalex   +1 more source