Results 121 to 130 of about 5,061,790 (379)
ACE2: Angiotensin II/Angiotensin-(1–7) Balance in Cardiac and Renal Injury
Current Hypertension Reports, 2014 Our current recognition of the renin-angiotensin system is more convoluted than originally thought due to the discovery of multiple novel enzymes, peptides, and receptors inherent in this interactive biochemical cascade. Over the last decade, angiotensin-
J. Varagić +3 more
semanticscholar +1 more source
Mass-spectrometric identification of a novel angiotensin peptide in human plasma [PDF]
, 2007 Objective— Angiotensin peptides play a central role in cardiovascular physiology and pathology. Among these peptides, angiotensin II (Ang II) has been investigated most intensively.
Bader, Michael +18 more
core +1 more source
A Case Report of Angiotensin II Use in the Treatment of Refractory Shock due to Amlodipine and Lisinopril Toxicity. [PDF]
Case Rep Crit CareConclusion: Despite evidence of efficacy in refractory vasodilatory shock secondary to sepsis, there is a paucity of data on the use of angiotensin II as an adjunctive vasopressor in drug-induced shock.
Keller JH, Kendric KJ, LeSaint KT.
europepmc +2 more sources
Advanced Science, EarlyView.PIK3CAH1047R DNA in colorectal cancer (CRC) cell‐derived exosomes can be delivered into recipient fibroblasts, where it is transcribed and translated, leading to the activation of fibroblasts into cancer‐associated fibroblasts, which secrete elevated levels of IL6. The simultaneous detection and targeting of PIK3CAH1047R mutation and IL6 may serve as a
Rui Wang +6 more
wiley +1 more source
Angiotensin II and Renal Tubular Ion Transport
The Scientific World Journal, 2005 Angiotensin II, a potent vasoconstrictor, also participates in the regulation of renal sodium and water excretion, not only via a myriad of effects on renal hemodynamics, glomerular filtration rate, and regulation of aldosterone secretion, but also via ...
Patricia Valles +2 more
doaj +1 more source
Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli
Kidney International, 2014 A key role for podocytes in the pathogenesis of proteinuric renal diseases has been established. Angiotensin II causes depolarization and increased intracellular calcium concentration in podocytes; members of the cation TRPC channels family, particularly
D. Ilatovskaya +6 more
semanticscholar +1 more source
Effect of dietary protein on the renin-angiotensin system in subtotally nephrectomized rats [PDF]
, 1990 Effect of dietary protein on the renin-angiotensin system in subtotally nephrectomized rats. Dietary protein restriction improves the course of renal disease in the remnant kidney model.
Hostetter, Thomas H. +2 more
core +1 more source
Advanced Science, EarlyView.Aortic dissection (AD) is accompanied by a decrease in CCDC80 in vascular smooth muscle cells (VSMCs). CCDC80 can interact with JAK2, and VSMC‐specific CCDC80 deficiency accelerates the progression of AD by activating the JAK2/STAT3 pathway involved in regulating the phenotype switching and function of VSMCs.
Qingqing Xiao +18 more
wiley +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 BackgroundThe classical renin‐angiotensin system is known as the angiotensin (Ang)‐converting enzyme/Ang II/Ang type 1 receptor axis, which induces various organ damage including cognitive decline.
Akinori Higaki +12 more
doaj +1 more source
Searching inhibitors for three important proteins of COVID-19 through molecular docking studies [PDF]
arXiv, 2020 The lack of recommended drugs or vaccines to deal with the COVID-19 is the main concern of this pandemic. The approved drugs for similar health problems, drugs under clinical trials, and molecules from medicinal plants extracts are investigated randomly to deal with the COVID-19 infection.
arxiv