Results 151 to 160 of about 262,681 (286)

Withaferin A Attenuates Muscle Cachexia Induced by Angiotensin II Through Regulating Pathways Activated by Angiotensin II. [PDF]

Cells
Kakar SS, Vemuri V, Ratajczak MZ.
europepmc   +1 more source

Inflammation pathways as therapeutic targets in angiotensin II induced atrial fibrillation. [PDF]

Front Pharmacol
Hou A, Shi D, Huang H, Liu Y, Zhang Y.
europepmc   +1 more source

A Phase 1C, Open Label, Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of DM199 Administered Intravenously with a Polyvinyl Chloride Bag in Adult Healthy Subjects and Adults Recently Taking Angiotensin‐Converting Enzyme Inhibitors

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This small phase 1C, open‐label, single ascending dose study evaluated the safety, tolerability, and pharmacokinetics (PKs) of DM199, a recombinant form of human tissue kallikrein‐1 (KLK1). A small sample size of both healthy subjects and hypertensive adults recently taking angiotensin‐converting enzyme inhibitors was studied. KLK1 has a known
Michael Giuffre, Annette D. Lista, Nick Paulson, Lorianne Masuoka   +3 more
wiley   +1 more source

Renin Is Essential for Angiotensin II Formation in the Brain. [PDF]

J Am Heart Assoc
Rodrigues AF, Domenig O, Garrelds IM, Danser AHJ, Alenina N, Poglitsch M, Bader M.   +6 more
europepmc   +1 more source

Naringin attenuates angiotensin II induced cardiac hypertrophy by inhibiting carbonic anhydrase II. [PDF]

Sci Rep
Mahadevaswamy M, Suchitha GP, Pavan SR, Vivek HK, Nithya SD, Chandan S, Prasad SK, Keshava Prasad TS, Ahmad SF, Attia SM, Dagamajalu S, Siddesha JM.   +11 more
europepmc   +1 more source

Drug‐Event Pairs as Indicators for the Detection of Adverse Drug Reactions during Hospitalization in Routinely Collected Electronic Data Sources

Clinical Pharmacology &Therapeutics, EarlyView.
Adverse drug reactions (ADRs) are a common cause of morbidity and mortality in hospitalized patients. Identification of ADRs in clinical practice, surveillance and research is essential to prevent further harm. The aim of this study was to assess the likelihood of drugs contributing to clinically important inpatient adverse events, in order to provide ...
Anna Maria Wermund, Annette Haerdtlein, Wolfgang Fehrmann, Clara Weglage, Tobias Dreischulte, Ulrich Jaehde   +5 more
wiley   +1 more source

Angiotensin II Promotes Osteocyte RANKL Expression via AT1R Activation. [PDF]

Biomedicines
Ren J, Marahleh A, Ma J, Ohori F, Noguchi T, Fan Z, Hu J, Narita K, Lin A, Kitaura H.   +9 more
europepmc   +1 more source

Effects of Dimenhydrinate on Motor Behavior and Vascular Function: Possible Implications for the Field of Sports

Drug Testing and Analysis, EarlyView.
Regarding cardiovascular effects, DMH decreased vascular reactivity to phenylephrine and acetylcholine. We observed that the combination of DPH and 8‐Cl‐T was identified as the responsible for increasing blood pressure and heart rate in the biological model used.
Jazmín Flores‐Monroy, Diana Ramírez‐Hernández, Diego Lezama‐Martínez, Benjamín Velasco‐Bejarano   +3 more
wiley   +1 more source

Direct Vascular Effects of Angiotensin II (A Systematic Short Review). [PDF]

Int J Mol Sci
Nádasy GL, Balla A, Dörnyei G, Hunyady L, Szekeres M.   +4 more
europepmc   +1 more source

Refractory heart failure due to acquired aortic coarctation after total arch replacement: find the right antidote!

ESC Heart Failure, EarlyView.
Abstract A 31‐year‐old male presented with unexplainable symptoms of heart failure including recurrent fatigue and orthopnoea after total arch replacement for type A aortic dissection 2 months ago. Computed tomography angiography detected a severe intra‐luminal stenosis, and we successfully implanted a balloon‐expandable stent to dilate the stenosis ...
Yi Xie, Chen Lu, Jia Hu
wiley   +1 more source