Results 171 to 180 of about 5,061,790 (379)

Insights into new mechanosensitive behaviors of G protein-coupled receptors [PDF]

open access: yesarXiv
G protein-coupled receptors (GPCRs) represent a diverse and vital family of membrane proteins that mediate intracellular signaling in response to extracellular stimuli, playing critical roles in physiology and disease. Traditionally recognized as chemical signal transducers, GPCRs have recently been implicated in mechanotransduction, the process of ...
arxiv  

Modeling of Radiation Pneumonitis after Lung Stereotactic Body Radiotherapy: A Bayesian Network Approach [PDF]

open access: yesarXiv, 2015
Background and Purpose: Stereotactic body radiotherapy (SBRT) for lung cancer accompanies a non-negligible risk of radiation pneumonitis (RP). This study presents a Bayesian network (BN) model that connects biological, dosimetric, and clinical RP risk factors.
arxiv  

Blood Angiotensin II Levels of Normal and Hypertensive Subjects [PDF]

open access: green, 1969
K. J. Catt   +3 more
openalex   +1 more source

An Immunosenescent CD8+ T Cell Subset in Patients with Axial Spondyloarthritis and Psoriatic Arthritis Links Spontaneous Motility to Telomere Shortening and Dysfunction

open access: yesArthritis &Rheumatology, EarlyView.
Objective A pathogenetic role of CD8+ T lymphocytes in radiographic axial spondyloarthritis (r‐axSpA) and other spondyloarthritis (SpA) is sustained by genome‐wide association studies and by the expansion of public T cell clonotypes in the target tissues.
Giorgia Paldino   +16 more
wiley   +1 more source

Individualized Treatment Effects with Censored Data via Fully Nonparametric Bayesian Accelerated Failure Time Models [PDF]

open access: yesarXiv, 2017
Individuals often respond differently to identical treatments, and characterizing such variability in treatment response is an important aim in the practice of personalized medicine. In this article, we describe a non-parametric accelerated failure time model that can be used to analyze heterogeneous treatment effects (HTE) when patient outcomes are ...
arxiv  

A critical appraisal of the intrinsic pancreatic angiotensin-generating system [PDF]

open access: yes, 2001
The pancreas is a relative newcomer to the stable of tissues with an intrinsic angiotensin-generating system. The involvement of this system in pancreatic activity will be dependent on the angiotensin-generating paths present in the pancreas and their ...
Sernia, Conrad
core  

Studies on Erythropoietic Action of Angiotensin II [PDF]

open access: bronze, 1967
Kiku Nakao   +3 more
openalex   +1 more source

Serum Type I Interferon Score for Prediction of Clinically Meaningful Disease Progression in Limited Cutaneous Systemic Sclerosis

open access: yesArthritis &Rheumatology, EarlyView.
Objective To assess the value of serum type I interferon (IFN) score in predicting clinically meaningful progression in limited cutaneous systemic sclerosis (lcSSc) using a novel composite endpoint adopted from the MINIMISE clinical trial. Methods A retrospective, longitudinal lcSSc cohort was identified within a national, multicenter observational ...
Stefano Di Donato   +9 more
wiley   +1 more source

ACE inhibitors – angiotensin II receptor antagonists: A useful combination therapy for ischemic heart disease

open access: yesOpen Access Emergency Medicine, 2010
T S Mohamed Saleem1, K Bharani1, K Gauthaman21Department of Pharmacology, Annamacharya College of Pharmacy, Rajampet-516126, Kadapa Dist, Andhra Pradesh, India; 2Department of Drug Technology, Higher Institute of Medical Technology, Derna, LibyaAbstract:
T S Mohamed Saleem   +2 more
doaj  

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