Results 271 to 280 of about 4,889,938 (291)

The emerging role of Nrf2 in heart failure: From cardioprotection to therapeutic approaches

ESC Heart Failure, EarlyView.
Nrf2 signalling is impaired in heart failure, contributing to oxidative stress, mitochondrial dysfunction, and ferroptosis, which drive neurohormonal activation, inflammation, and ischaemia‐reperfusion injury. This loss of Nrf2 activity exacerbates hypertension, diabetic cardiomyopathy, and cardiotoxicity, accelerating progression to overt heart ...
Emiliano Fiori, Sergio Davinelli, Armando Ferrera, Alessandro Medoro, Carlo Barsali, Allegra Battistoni, Maurizio Volterrani, Massimo Volpe, Luciano Saso, Speranza Rubattu   +9 more
wiley   +1 more source

Ac-SDKP and eplerenone confer additive cardioprotection against angiotensin II-induced cardiac injury in C57BL/6J mice. [PDF]

J Mol Cell Cardiol Plus
Hamid S, Sarkar S, Peng H, Khalid M, Ortiz PA, Xu J, Liao TD, Knight RA, Rhaleb NE.   +8 more
europepmc   +1 more source

Nephrological perspectives on the underutilization of SGLT2is in heart failure and chronic kidney disease

ESC Heart Failure, Volume 12, Issue 2, Page 1490-1491, April 2025.
Özant Helvacı, Ömer Faruk Akçay, Emre Yaşar, Ülver Derici, Galip Güz   +4 more
wiley   +1 more source

A novel treatment score (QUAD score) to promote treatment optimization in heart failure with a reduced ejection fraction

ESC Heart Failure, EarlyView.
The QUAD score was developed to promote adherence to clinical practice guidelines for patients with heart failure and a reduced left ventricular ejection fraction <50%. In newly diagnosed patients who had completed therapy titration, we found that patients with an excellent QUAD score had a significant reduction in the risk of mortality or ...
Henry Oluwasefunmi Savage, Jason N. Dungu, Anthony Dimarco, Brian Li, Samantha Langley, Jonathan Kojo Amoah, Paraic Cliffe, Archana Ganapathy, Peter Watters, Patricia Campbell, Nicola Melarkey, Simon Duckett, Sean Davies, Matthew Dewhurst, Karen Hann, Louise Clayton, Rhys Williams, Victoria Ruszala, Teresa Onwere‐Tan, Fozia Zahir Ahmed, Ibrahim Arosi, Kimberly Gray, Mark C. Petrie, John G.F. Cleland   +23 more
wiley   +1 more source

Temporal complexity of LVV-hemorphin-7 allosterism at the angiotensin II type 1 receptor assessed using entropy-based approaches. [PDF]

Comput Struct Biotechnol J
Jelinek HF, Johnson MP, Khan FB, Elgendi M, Ayoub MA.   +4 more
europepmc   +1 more source

Renin Is Essential for Angiotensin II Formation in the Brain. [PDF]

J Am Heart Assoc
Rodrigues AF, Domenig O, Garrelds IM, Danser AHJ, Alenina N, Poglitsch M, Bader M.   +6 more
europepmc   +1 more source

Association between timing of angiotensin II administration and outcomes in vasoplegia after cardiac surgery. [PDF]

JTCVS Open
Miles TJ, Guinn MT, Suero OR, Rosengart TK, Moon MR, Coselli JS, Ghanta RK, Chatterjee S.   +7 more
europepmc   +1 more source

Effects of Angiotensin II Receptor 1 Inhibition by LCZ696 on the Acquisition and Relapse of Methamphetamine-Associated Contextual Memory. [PDF]

Pharmaceuticals (Basel)
Li X, Zou Z, Yang X, Lü J, Zhang X, Zhou J, Zhu D, Gong X, Lin S, Yu Z, Si Z, Wei W, Xie Y, Liu Y.   +13 more
europepmc   +1 more source