Results 41 to 50 of about 5,964,638 (304)
Angiotensin II and Renal Fibrosis [PDF]
Abstract — — Angiotensin (Ang) II, the main peptide of the renin angiotensin system (RAS), is a renal growth factor, inducing hyperplasia/hypertrophy depending on the cell type. This vasoactive peptide activates mesangial and tubular cells and interstitial fibroblasts, increasing the ...
Mezzano, SA, Ruiz-Ortega, M, Egido, J
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Angiotensin II in septic shock [PDF]
This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2015 and co-published as a series in Critical Care. Other articles in the series can be found online at http://ccforum.com/series/annualupdate2015.
Corrêa TD, Takala J, Jakob SM
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Role of Angiotensin Receptor Type I and Type II in the Development of Common Cardiac Problems
The renin–angiotensin system is crucial for maintaining blood pressure and fluid balance. Central to this system are the angiotensin receptors, type I (AT1R) and type II (AT2R), which mediate the effects of angiotensin II (Ang-II).
Tannistha Hota +2 more
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The structure of testis angiotensin-converting enzyme (tACE-g13) in complex with the inhibitor RXPA380 [PDF]
Includes bibliographical references.Angiotensin-converting enzyme (ACE), a zinc metalloprotease, is a key regulator of the mammalian renin-angiotensin system (RAS) Primarily, ACF is a dipeptidl peptidase which cleaves angiotensin I to produce angiotensin
Chitapi, Itai
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Investigating the mechanisms of atherosclerosis, the number one cause of death in the civilized world, is an arduous task. During the last 5 decades, many aspects of atherosclerotic lesion development have been revealed and many hypotheses have been tested.
Cornelius F.H. Mueller, Georg Nickenig
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Introduction. The sarcoplasmic reticulum Ca2+ ATPase (SERCA) is essential for the regulation of the intracellular calcium level in cardiomyocytes. Previous studies have found that angiotensin 11 (Ang II) decreased SERCA2 gene expression in ventricular ...
吳卓鍇;曾春典;黃尹岑;謝佳珊;蔡維珊;林俊立;江福田;蔡佳醍 +1 more
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Angiogenesis "in vitro" of the healthy mouse heart under hypoxia : the role of Angiotensin II and Nitric Oxide [PDF]
Angiogenesis is the process by which blood microvessels are formed from existing ones. Angiogenesis is required for development. It is also important for reducing myocardial hypoxia due to coronary and ischemic heart disease; in myocardial infarction ...
Munk, Veronica Cecilia
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Hypoxia-induced signaling in angiogenesis : role of mTOR, HIF and Angiotensin II [PDF]
This thesis includes the work of four different projects I have been following during my time as a PhD student; (1) the characterization of mTOR-associated signaling and endothelial cell proliferation in response to hypoxia, and (2) identification of ...
Petrimpol, Marco Renato
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IntroductionTwin gestation is related to a higher risk of hypertensive disorders in pregnancy with possible risk stratification depending on chorionicity.
Paweł Pietruski +6 more
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Electronic sculpting of ligand-GPCR subtype selectivity:the case of angiotensin II [PDF]
GPCR subtypes possess distinct functional and pharmacological profiles, and thus development of subtype-selective ligands has immense therapeutic potential.
Pappas, Charalampos G. +41 more
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