Results 31 to 40 of about 5,964,638 (304)

Angiotensin II and the Heart [PDF]

open access: yesHypertension, 2000
Abstract—The active end product of the renin-angiotensin system, angiotensin II (Ang II), through the activation of specific Ang II receptors, regulates cardiac contractility, cell coupling, and impulse propagation and is involved in cardiac remodeling, growth, and apoptosis. We review these subjects, as well as the second messengers that are involved,
de Mello, WC, Danser, Jan
openaire   +3 more sources

Role of protein kinase C in renal vasoconstriction caused by angiotensin II [PDF]

open access: yes, 1990
In this study we have examined the subcellar pathways along which angiotensin II (ANG II) causes renal vasoconstriction. Using the isolated perfused rat kidney model, we found that renal vasoconstriction produced by ANG II (100 pM) was not altered by the
Kurtz, Armin   +3 more
core   +1 more source

The hyperglycemia induced by angiotensin II in rats is mediated by AT1 receptors

open access: yesBrazilian Journal of Medical and Biological Research, 1998
We have shown that the renin-angiotensin system (RAS) is involved in glucose homeostasis during acute hemorrhage. Since almost all of the physiological actions described for angiotensin II were mediated by AT1 receptors, the present experiments were ...
L.J.C. Machado   +3 more
doaj   +1 more source

Analysis of the Vasorelaxant Action of Angiotensin II in the Isolated Rat Renal Artery

open access: yesJournal of Pharmacological Sciences, 2008
Taking into consideration that mechanisms involved in the vasodilatator actions of angiotensin II have not yet been completely elucidated, the present study was undertaken in order to examine the mechanisms underlying the angiotensin II–induced ...
Leposava Grbović   +3 more
doaj   +1 more source

Neohesperidin Protects Angiotensin II-Induced Hypertension and Vascular Remodeling

open access: yesFrontiers in Pharmacology, 2022
Vascular remodeling due to hypertension is one of the major health challenges facing countries around the world. Neohesperidin, a flavonoid glycoside found in citrus fruits, is an antioxidant.
Jingsi Zhang   +7 more
doaj   +1 more source

Angiotensin II Antagonists

open access: yesClinical and Experimental Hypertension, 1993
Acute blockade of the renin-angiotensin system with the parenterally active angiotensin II antagonist saralasin has been shown to effectively lower blood pressure in a large fraction of patients with essential hypertension and to improve hemodynamics in some patients with congestive heart failure.
Brunner HR   +3 more
openaire   +3 more sources

Detrimental Effects of Centrally Administered Angiotensin II are Enhanced in a Mouse Model of Alzheimer Disease Independently of Blood Pressure

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundThe significance of brain angiotensin II in Alzheimer disease (AD) is unclear. Methods and ResultsTo examine the role of brain angiotensin II in AD, intracerebroventricular angiotensin II infusion was performed on 5XFAD mice, a mouse model of ...
Koki Takane   +6 more
doaj   +1 more source

Angiotensin II and Erythropoiesis.

open access: yesExperimental Biology and Medicine, 1963
Summary1. Polycythemic mice and hypophysectomized rats were used as assay animals to measure the erythropoietic stimulating activity of synthetic angiotensin II (A-S) and of angiotensin II made from a crude extract of the hog kidney (A-CE). 2. No increase in erythropoietic activity, as measured by the red blood cell incorporation of Fe59, was found ...
Y C, BILSEL, J E, WOOD, R D, LANGE
openaire   +2 more sources

Pathological Role of Angiotensin II in Severe COVID-19

open access: yesTH Open, 2020
The activated renin–angiotensin system induces a prothrombotic state resulting from the imbalance between coagulation and fibrinolysis. Angiotensin II is the central effector molecule of the activated renin–angiotensin system and is degraded by the ...
Wolfgang Miesbach
doaj   +1 more source

Angiotensin II induces cholesterol accumulation and impairs insulin secretion by regulating ABCA1 in beta cells

open access: yesJournal of Lipid Research, 2018
In pancreatic β cells, ABCA1, a 254 kDa membrane protein, affects cholesterol homeostasis and insulin secretion. Angiotensin II, as the main effector of the renin–angiotensin system, decreases glucose-stimulated insulin secretion (GSIS).
Jingya Lyu   +11 more
doaj   +1 more source

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