Results 31 to 40 of about 6,209,552 (299)
Angiotensin II impairs endothelial function via tyrosine phosphorylation of the endothelial nitric oxide synthase [PDF]
Proline-rich tyrosine kinase 2 (PYK2) can be activated by angiotensin II (Ang II) and reactive oxygen species. We report that in endothelial cells, Ang II enhances the tyrosine phosphorylation of endothelial NO synthase (eNOS) in an AT1-, H2O2-, and PYK2-
Loot, Annemarieke E. +7 more
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Angiotensin II and Renal Fibrosis [PDF]
Abstract — — Angiotensin (Ang) II, the main peptide of the renin angiotensin system (RAS), is a renal growth factor, inducing hyperplasia/hypertrophy depending on the cell type. This vasoactive peptide activates mesangial and tubular cells and interstitial fibroblasts, increasing the ...
Mezzano, SA, Ruiz-Ortega, M, Egido, J
openaire +4 more sources
Analysis of the Vasorelaxant Action of Angiotensin II in the Isolated Rat Renal Artery
Taking into consideration that mechanisms involved in the vasodilatator actions of angiotensin II have not yet been completely elucidated, the present study was undertaken in order to examine the mechanisms underlying the angiotensin II–induced ...
Leposava Grbović +3 more
doaj +1 more source
Angiotensin II in septic shock [PDF]
This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2015 and co-published as a series in Critical Care. Other articles in the series can be found online at http://ccforum.com/series/annualupdate2015.
Corrêa TD, Takala J, Jakob SM
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Role of Angiotensin Receptor Type I and Type II in the Development of Common Cardiac Problems
The renin–angiotensin system is crucial for maintaining blood pressure and fluid balance. Central to this system are the angiotensin receptors, type I (AT1R) and type II (AT2R), which mediate the effects of angiotensin II (Ang-II).
Tannistha Hota +2 more
doaj +1 more source
Neohesperidin Protects Angiotensin II-Induced Hypertension and Vascular Remodeling
Vascular remodeling due to hypertension is one of the major health challenges facing countries around the world. Neohesperidin, a flavonoid glycoside found in citrus fruits, is an antioxidant.
Jingsi Zhang +7 more
doaj +1 more source
Investigating the mechanisms of atherosclerosis, the number one cause of death in the civilized world, is an arduous task. During the last 5 decades, many aspects of atherosclerotic lesion development have been revealed and many hypotheses have been tested.
Cornelius F.H. Mueller, Georg Nickenig
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Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice [PDF]
Obesity is closely associated with the metabolic syndrome, a combination of disorders including insulin resistance, diabetes, dyslipidemia, and hypertension.
Kenyon, C J +35 more
core +1 more source
Pathological Role of Angiotensin II in Severe COVID-19
The activated renin–angiotensin system induces a prothrombotic state resulting from the imbalance between coagulation and fibrinolysis. Angiotensin II is the central effector molecule of the activated renin–angiotensin system and is degraded by the ...
Wolfgang Miesbach
doaj +1 more source
IntroductionTwin gestation is related to a higher risk of hypertensive disorders in pregnancy with possible risk stratification depending on chorionicity.
Paweł Pietruski +6 more
doaj +1 more source

