Results 11 to 20 of about 235,819 (313)

Angiotensin converting enzyme 2 (ACE2) - the major receptor for SARS-CoV-2 virus [PDF]

open access: yesFarmacja Polska, 2021
The renin-angiotensin-aldosterone system (RAS) plays a significant role in the regulation of the water and electrolyte balance. Renin from the kidneys converts angiotensinogen to angiotensin I. Angiotensin converting enzyme (ACE) catalyzes the conversion
Sonia Frankowska   +3 more
doaj   +1 more source

Angiotensin II [PDF]

open access: yesHospital Pharmacy, 2018
Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing ...
Danial E, Baker, Terri L, Levien
openaire   +2 more sources

The radioimmunoassay of angiotensin II [PDF]

open access: yesProceedings of the Royal Society of London. Series B. Biological Sciences, 1969
Abstract Specific antibody against free angiotensin II has been raised in high titre by immunizing rabbits with angiotensin II amide (‘Hypertensin’, Ciba) adsorbed on to micro-particles of carbon. The material was injected either parenterally or directly into lymph nodes and spleen.
G W, Boyd, J, Landon, W S, Peart
openaire   +2 more sources

Prolylcarboxypeptidase Alleviates Hypertensive Cardiac Remodeling by Regulating Myocardial Tissue Angiotensin II

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Prolonged activation of angiotensin II is the main mediator that contributes to the development of heart diseases, so converting angiotensin II into angiotensin 1‐7 has emerged as a new strategy to attenuate detrimental effects of angiotensin ...
Binh Y. Nguyen   +15 more
doaj   +1 more source

From Angiotensin II to Cyclic Peptides and Angiotensin Receptor Blockers (ARBs): Perspectives of ARBs in COVID-19 Therapy

open access: yesMolecules, 2021
The octapeptide hormone angiotensin II is one of the most studied peptides with the aim of designing and synthesizing non-peptide mimetics for oral administration.
John Matsoukas   +6 more
doaj   +1 more source

Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors. [PDF]

open access: yesPLoS ONE, 2014
INTRODUCTION: Recently, we could show that angiotensin II, the reactive peptide of the blood pressure-regulating renin-angiotensin-aldosterone-system, causes the formation of reactive oxygen species and DNA damage in kidneys and hearts of hypertensive ...
Susanne Brand   +4 more
doaj   +1 more source

Signaling of angiotensin II-induced vascular protein synthesis in conduit and resistance arteries in vivo [PDF]

open access: yes, 2004
<b>Background</b> From in vitro studies, it has become clear that several signaling cascades are involved in angiotensin II-induced cellular hypertrophy.
Martens Fabrice MAC   +23 more
core   +1 more source

Structural determinants for binding to angiotensin converting enzyme 2 (ACE2) and angiotensin receptors

open access: yesFrontiers in Pharmacology, 2015
Angiotensin converting enzyme 2 (ACE2) is a zinc carboxypeptidase involved in the renin angiotensin system (RAS) and inactivates the potent vasopressive peptide angiotensin II (Ang II) by removing the C-terminal phenylalanine residue to yield Ang1-7 ...
Daniel eClayton   +6 more
doaj   +1 more source

Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancy [PDF]

open access: yes, 2007
Maternal endothelial dysfunction in preeclampsia is associated with increased soluble fms-like tyrosine kinase-1 (sFlt-1), a circulating antagonist of vascular endothelial growth factor and placental growth factor.
Kellems, Rodney E.   +19 more
core   +1 more source

Advance in Research of Angiotensin II and Its Receptor and Malignant Tumor

open access: yesChinese Journal of Lung Cancer, 2016
Angiotensin AngII, a linear small peptide,which is composed of eight amino acids, is the main effectors of renin-angiotensin systen (Renin-angiotensin system, RAS).
Lulu SUN, Jian SHI
doaj   +1 more source

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