Results 11 to 20 of about 6,209,552 (299)
DIOL triterpenes block profibrotic effects of angiotensin II and protect from cardiac hypertrophy.
BackgroundThe natural triterpenes, erythrodiol and uvaol, exert anti-inflammatory, vasorelaxing and anti-proliferative effects. Angiotensin II is a well-known profibrotic and proliferative agent that participates in the cardiac remodeling associated with
Ruben Martín +11 more
doaj +2 more sources
T S Mohamed Saleem1, K Bharani1, K Gauthaman21Department of Pharmacology, Annamacharya College of Pharmacy, Rajampet-516126, Kadapa Dist, Andhra Pradesh, India; 2Department of Drug Technology, Higher Institute of Medical Technology, Derna, LibyaAbstract:
T S Mohamed Saleem +2 more
doaj +1 more source
Angiotensin II (Ang II) infusion into rats elevates local angiotensin II levels through an AT1 receptor–dependent pathway in the kidney. We examined whether treatment with an angiotensin-converting enzyme (ACE) inhibitor, temocapril, or an AT1-receptor ...
Keisuke Ohnishi +12 more
doaj +2 more sources
Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing ...
Danial E, Baker, Terri L, Levien
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The radioimmunoassay of angiotensin II [PDF]
Abstract Specific antibody against free angiotensin II has been raised in high titre by immunizing rabbits with angiotensin II amide (‘Hypertensin’, Ciba) adsorbed on to micro-particles of carbon. The material was injected either parenterally or directly into lymph nodes and spleen.
G W, Boyd, J, Landon, W S, Peart
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Signaling of angiotensin II-induced vascular protein synthesis in conduit and resistance arteries in vivo [PDF]
<b>Background</b> From in vitro studies, it has become clear that several signaling cascades are involved in angiotensin II-induced cellular hypertrophy.
Martens Fabrice MAC +23 more
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Adenoviral delivery of angiotensin-(1-7) or angiotensin-(1-9) inhibits cardiomyocyte hypertrophy via the mas or angiotensin Type 2 receptor [PDF]
The counter-regulatory axis of the renin angiotensin system peptide angiotensin-(1-7) [Ang-(1-7)] has been identified as a potential therapeutic target in cardiac remodelling, acting via the mas receptor.
Nicklin Stuart A. +11 more
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Effects of Circulating and Local Uteroplacental Angiotensin II in Rat Pregnancy. [PDF]
The renin-angiotensin (Ang) system is important during placental development. Dysregulation of the renin-Ang system is important in preeclampsia (PE). Female rats transgenic for the human angiotensinogen gene crossed with males transgenic for the human ...
Muller, DN +38 more
core +1 more source
Angiotensin II Moderately Decreases Plasmodium Infection and Experimental Cerebral Malaria in Mice. [PDF]
Angiotensin II, a peptide hormone that regulates blood pressure, has been proposed as a protective factor against cerebral malaria based on a genetic analysis.
Julio Gallego-Delgado +7 more
doaj +1 more source
Angiotensin II and the Heart [PDF]
Abstract—The active end product of the renin-angiotensin system, angiotensin II (Ang II), through the activation of specific Ang II receptors, regulates cardiac contractility, cell coupling, and impulse propagation and is involved in cardiac remodeling, growth, and apoptosis. We review these subjects, as well as the second messengers that are involved,
de Mello, WC, Danser, Jan
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