Results 21 to 30 of about 235,819 (313)

Detrimental Effects of Centrally Administered Angiotensin II are Enhanced in a Mouse Model of Alzheimer Disease Independently of Blood Pressure

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundThe significance of brain angiotensin II in Alzheimer disease (AD) is unclear. Methods and ResultsTo examine the role of brain angiotensin II in AD, intracerebroventricular angiotensin II infusion was performed on 5XFAD mice, a mouse model of ...
Koki Takane   +6 more
doaj   +1 more source

Adenoviral delivery of angiotensin-(1-7) or angiotensin-(1-9) inhibits cardiomyocyte hypertrophy via the mas or angiotensin Type 2 receptor [PDF]

open access: yes, 2012
The counter-regulatory axis of the renin angiotensin system peptide angiotensin-(1-7) [Ang-(1-7)] has been identified as a potential therapeutic target in cardiac remodelling, acting via the mas receptor.
Nicklin Stuart A.   +11 more
core   +1 more source

Angiotensin II and the Heart [PDF]

open access: yesHypertension, 2000
Abstract—The active end product of the renin-angiotensin system, angiotensin II (Ang II), through the activation of specific Ang II receptors, regulates cardiac contractility, cell coupling, and impulse propagation and is involved in cardiac remodeling, growth, and apoptosis. We review these subjects, as well as the second messengers that are involved,
de Mello, WC, Danser, Jan
openaire   +3 more sources

Angiotensin II induces cholesterol accumulation and impairs insulin secretion by regulating ABCA1 in beta cells

open access: yesJournal of Lipid Research, 2018
In pancreatic β cells, ABCA1, a 254 kDa membrane protein, affects cholesterol homeostasis and insulin secretion. Angiotensin II, as the main effector of the renin–angiotensin system, decreases glucose-stimulated insulin secretion (GSIS).
Jingya Lyu   +11 more
doaj   +1 more source

Angiotensin II Moderately Decreases Plasmodium Infection and Experimental Cerebral Malaria in Mice. [PDF]

open access: yesPLoS ONE, 2015
Angiotensin II, a peptide hormone that regulates blood pressure, has been proposed as a protective factor against cerebral malaria based on a genetic analysis.
Julio Gallego-Delgado   +7 more
doaj   +1 more source

Angiotensin II facilitates fibrogenic effect of TGF-β1 through enhancing the down-regulation of BAMBI caused by LPS: a new pro-fibrotic mechanism of angiotensin II. [PDF]

open access: yesPLoS ONE, 2013
Angiotensin II has progressively been considered to play an important role in the development of liver fibrosis, although the mechanism isn't fully understood.
Yu-Sheng Li   +6 more
doaj   +1 more source

Role of protein kinase C in renal vasoconstriction caused by angiotensin II [PDF]

open access: yes, 1990
In this study we have examined the subcellar pathways along which angiotensin II (ANG II) causes renal vasoconstriction. Using the isolated perfused rat kidney model, we found that renal vasoconstriction produced by ANG II (100 pM) was not altered by the
Kurtz, Armin   +3 more
core   +1 more source

Analysis of the Vasorelaxant Action of Angiotensin II in the Isolated Rat Renal Artery

open access: yesJournal of Pharmacological Sciences, 2008
Taking into consideration that mechanisms involved in the vasodilatator actions of angiotensin II have not yet been completely elucidated, the present study was undertaken in order to examine the mechanisms underlying the angiotensin II–induced ...
Leposava Grbović   +3 more
doaj   +1 more source

Neohesperidin Protects Angiotensin II-Induced Hypertension and Vascular Remodeling

open access: yesFrontiers in Pharmacology, 2022
Vascular remodeling due to hypertension is one of the major health challenges facing countries around the world. Neohesperidin, a flavonoid glycoside found in citrus fruits, is an antioxidant.
Jingsi Zhang   +7 more
doaj   +1 more source

Angiotensin II and Erythropoiesis.

open access: yesExperimental Biology and Medicine, 1963
Summary1. Polycythemic mice and hypophysectomized rats were used as assay animals to measure the erythropoietic stimulating activity of synthetic angiotensin II (A-S) and of angiotensin II made from a crude extract of the hog kidney (A-CE). 2. No increase in erythropoietic activity, as measured by the red blood cell incorporation of Fe59, was found ...
Y C, BILSEL, J E, WOOD, R D, LANGE
openaire   +2 more sources

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