Results 1 to 10 of about 114,228 (331)
Angiotensin II receptor antagonists
Lancet, The, 2000 Blockade of the renin-angiotensin system began as a way of studying the pathogenesis of cardiovascular disease with specific pharmacological probes. Oral activity, achieved by shortening the original peptide structures, transformed the probes into therapeutic agents, the angiotensin-converting enzyme (ACE) inhibitors.
Michel Burnier, H R Brunner
exaly +8 more sources
Angiotensin II-receptor antagonists: An overview [PDF]
American Journal of Health-System Pharmacy, 2000 Angiotensin II (AT-II)-receptor antagonists are reviewed. Research focused on blocking the renin-angiotensin system (RAS) led to the discovery of angiotensin-converting-enzyme (ACE) inhibitors, which are effective in the treatment of hypertension but are associated with a high frequency of cough and other adverse effects.
Dina, Raquel, Jafari, Mahtab
core +6 more sources
Spectrofluorimetric method for determination of some angiotensin II receptor antagonists
Journal of Pharmaceutical Analysis, 2012 A simple, rapid, accurate and highly sensitive spectrofluorimetric method has been developed for determination of some angiotensin II receptor antagonists (AIIRA's), namely Losartan potassium (Los-K), Irbesartan (Irb), Valsartan (Val) and Candesartan ...
Salwa R. El-Shaboury +3 more
doaj +4 more sources
Angiotensin II receptor antagonists in hypertension [PDF]
Kidney International, 1998 Blockade of the renin-angiotensin system is now recognized as an effective approach to the treatment of hypertension and congestive heart failure. Today, it is possible to antagonize the effects of angiotensin II more specifically by blocking its receptors by using nonpeptide receptor antagonists.
Burnier M, Brunner HR
core +5 more sources
Discontinuation of Heart Failure Pharmacotherapy in Older Adults With Frailty [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Guideline‐directed medical therapy (GDMT) improves outcomes in heart failure irrespective of frailty status. Nevertheless, the magnitude of frailty‐associated discontinuation of GDMT remains insufficiently studied.
Ryo Nakamaru +5 more
doaj +2 more sources
Comparison of angiotensin II receptor antagonists [PDF]
European Journal of Clinical Investigation, 2001 Nonpeptide orally active angiotensin II type 1 (AT1) receptor antagonists are the most specific means presently available to block the renin‐angiotensin enzymatic cascade. Six of these drugs have already been licensed in Europe and in the United States for the treatment of high blood pressure, and additional candidates are in the pipeline.
W, Kirch, B, Horn, J, Schweizer
exaly +3 more sources
Open Access Emergency Medicine, 2010 T S Mohamed Saleem1, K Bharani1, K Gauthaman21Department of Pharmacology, Annamacharya College of Pharmacy, Rajampet-516126, Kadapa Dist, Andhra Pradesh, India; 2Department of Drug Technology, Higher Institute of Medical Technology, Derna, LibyaAbstract:
T S Mohamed Saleem +2 more
doaj +1 more source
ANGIOTENSIN RECEPTOR ANTAGONISTS: GOING WITH THE TIMES
Кардиоваскулярная терапия и профилактика, 2013 This literature review focuses on the angiotensin II receptor antagonists as one of the new and promising classes of antihypertensive medications. Apart from their antihypertensive activity, these agents possess a number of other beneficial effects.
E. O. Taratukhin
doaj +3 more sources
ANGIOTENSIN II RECEPTOR ANTAGONISTS AND PROTEINURIA
Zdravniški Vestnik, 2002 Background. In numerous clinical studies that tried to identify risk factors for progressive renal function loss, the severity of proteinuria correlated with the rate of renal function loss.
Tanja Kök, Radovan Hojs
doaj +2 more sources
Patient Related Outcome Measures, 2011 Artavazd Tadevosyan1, Eric J MacLaughlin2, Vardan T Karamyan31Departments of Medicine, Montreal Heart Institute and Université de Montréal, Montreal, QC, Canada; 2Department of Pharmacy Practice, 3Department of Pharmaceutical ...
Artavazd Tadevosyan +2 more
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