Results 21 to 30 of about 183,641 (351)

ANGIOTENSIN II TYPE 1 RECEPTOR AUTOANTIBODIES

open access: yesJournal of Hypertension, 2019
Objective:Primary aldosteronism (PA), the most common cause of endocrine hypertension, is a disorder due to bilateral adrenal hyperplasia (BAH) and aldosterone producing adenoma (APA), featuring concentrations of plasma aldosterone that are inappropriately high for the circulating renin levels ...
M. Piazza   +4 more
openaire   +2 more sources

Functional Interaction between Angiotensin II Receptor Type 1 and Chemokine (C-C Motif) Receptor 2 with Implications for Chronic Kidney Disease

open access: yesPLoS ONE, 2015
Understanding functional interactions between G protein-coupled receptors is of great physiological and pathophysiological importance. Heteromerization provides one important potential mechanism for such interaction between different signalling pathways ...
M. Ayoub   +8 more
semanticscholar   +1 more source

Angiotensin II type 1 and type 2 receptor expression in circulating monocytes of diabetic and hypercholesterolemic patients over 3-month rosuvastatin treatment

open access: yesCardiovascular Diabetology, 2012
Background In diabetes, a variety of pro-inflammatory cellular changes has been found in various cell types, including monocytes which are known to be involved in all the phases of atherogenesis.
Marino Franca   +11 more
doaj   +1 more source

Enhancement of Adipocyte Browning by Angiotensin II Type 1 Receptor Blockade. [PDF]

open access: yesPLoS ONE, 2016
Browning of white adipose tissue (WAT) has been highlighted as a new possible therapeutic target for obesity, diabetes and lipid metabolic disorders, because WAT browning could increase energy expenditure and reduce adiposity.
Kana Tsukuda   +12 more
doaj   +1 more source

Immediate and Catastrophic Antibody‐Mediated Rejection in a Lung Transplant Recipient With Anti–Angiotensin II Receptor Type 1 and Anti–Endothelin‐1 Receptor Type A Antibodies

open access: yesAmerican Journal of Transplantation, 2017
Preexisting donor‐specific anti‐HLA antibodies (DSAs) have been associated with reduced survival of lung allografts. However, antibodies with specificities other than HLA may have a detrimental role on the lung transplant outcome. A young man with cystic
E. Cozzi   +8 more
semanticscholar   +1 more source

Angiotensin II Type 1 Receptor Gene Regulation [PDF]

open access: yesHypertension, 2007
Angiotensin II (Ang II), the major bioactive peptide of the renin–angiotensin system, was originally described as a potent vasoconstrictor. It is now recognized as a multifunctional hormone influencing many cellular processes, including cell growth, apoptosis, migration, inflammation, and fibrosis.1,2 Under pathological conditions, the vasoconstrictor,
Terry S, Elton, Mickey M, Martin
openaire   +2 more sources

Roles and functions of Atp6ap2 in the brain

open access: yesNeural Regeneration Research, 2018
The classical renin-angiotensin system (RAS) in the body has been studied intensively in the last decades, since it is known that this system is involved in the regulation of blood pressure.
Alexander Bracke   +1 more
doaj   +1 more source

Angiotensin II type 2 receptor–interacting protein 3a inhibits ovarian carcinoma metastasis via the extracellular HMGA2-mediated ERK/EMT pathway

open access: yesTumor Biology, 2017
Local migration and long-distance metastasis is the main reason for higher mortality of ovarian cancer. Microtubule-associated tumor suppressor 1/angiotensin II type 2 receptor–interacting protein is associated with tumor initiation and progression and ...
Ping Huang   +3 more
doaj   +1 more source

Angiotensin II receptor type 1 blockade decreases CTGF/CCN2-mediated damage and fibrosis in normal and dystrophic skeletal muscles

open access: yesJournal of Cellular and Molecular Medicine, 2012
Connective tissue growth factor (CTGF/CCN‐2) is mainly involved in the induction of extracellular matrix (ECM) proteins. The levels of CTGF correlate with the degree and severity of fibrosis in many tissues, including dystrophic skeletal muscle. The CTGF
C. Cabello-Verrugio   +4 more
semanticscholar   +1 more source

Cytokine Profiles Associated With Angiotensin II Type 1 Receptor Antibodies

open access: yesKidney International Reports, 2019
Introduction: Angiotensin II type 1 receptor antibody (AT1R-Ab), is a non–human leukocyte antigen (HLA) antibody implicated in poor renal allograft outcomes, although its actions may be mediated through a different pathway than HLA donor-specific ...
Meghan H. Pearl   +8 more
doaj   +1 more source

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