Results 31 to 40 of about 183,641 (351)

Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors. [PDF]

open access: yesPLoS ONE, 2014
INTRODUCTION: Recently, we could show that angiotensin II, the reactive peptide of the blood pressure-regulating renin-angiotensin-aldosterone-system, causes the formation of reactive oxygen species and DNA damage in kidneys and hearts of hypertensive ...
Susanne Brand   +4 more
doaj   +1 more source

Downregulation of Angiotensin II Type 1 Receptors During Sepsis [PDF]

open access: yesHypertension, 2001
Our study aimed to characterize the mechanisms underlying the attenuated cardiovascular responsiveness toward the renin-angiotensin system during sepsis. For this purpose, we determined the effects of experimental Gram-negative and Gram-positive sepsis in rats.
M, Bucher   +4 more
openaire   +2 more sources

The Angiotensin II Type 1 Receptor-Associated Protein Attenuates Angiotensin II-Mediated Inhibition of the Renal Outer Medullary Potassium Channel in Collecting Duct Cells

open access: yesFrontiers in Physiology, 2021
Adjustments in renal K+ excretion constitute a central mechanism for K+ homeostasis. The renal outer medullary potassium (ROMK) channel accounts for the major K+ secretory route in collecting ducts during basal conditions.
Juliano Zequini Polidoro   +2 more
doaj   +1 more source

ANGIOTENSIN II TYPE-1 RECEPTOR (AT1R) DISTRIBUTION IN BPH, HIGH GRADE PIN AND ADENOCARCINOMA OF THE PROSTATE

open access: yesJurnal Urologi Indonesia, 2016
Objective: The aim of the study was to detect the differences in number and the distribution of angiotensin II type-1 receptor (AT1R) in BPH, high grade PIN, and adenocarcinoma of the prostate. Material & method: A prospective study was performed in RSHS,
Isdianto Septiadi   +11 more
doaj   +1 more source

Losartan improved hippocampal long‐term potentiation impairment induced by repeated LPS injection in rats

open access: yesPhysiological Reports, 2021
Cognitive impairment has been known as a common consequence of brain inflammation. Long‐term potentiation (LTP), the generally accepted cellular mechanism for memory formation in the mammalian brain, has been shown to be suppressed by inflammation ...
Mahmoud Hosseini   +2 more
doaj   +1 more source

Angiotensin II type 1 receptor expression in human pancreatic cancer and growth inhibition by angiotensin II type 1 receptor antagonist [PDF]

open access: yesFEBS Letters, 2001
We investigated the expression of angiotensin II type 1 receptor (AT1) in pancreatic cancer. Both AT1 mRNA and protein were expressed in human pancreatic cancer tissues and cell lines. Binding assays showed that pancreatic cancer cells have specific binding sites for angiotensin II and that binding could be eliminated by treatment with a selective AT1 ...
Fujimoto, Yoshifumi   +3 more
openaire   +2 more sources

Angiotensin II type 1 receptor antagonists and their combinations in the treatment of hypertension

open access: yesSouth African Family Practice, 2012
No abstract available.
J.A. Ker
doaj   +1 more source

Assessment of cardiac hemodynamics indicators in patients with arterial hypertension and non-alcoholic fatty liver disease depending on angiotensin II type 1 receptor A1166C gene polymorphism

open access: yesZaporožskij Medicinskij Žurnal, 2018
Aim of study is to estimate the indicators of cardiac hemodynamics in patients with arterial hypertension and non-alcoholic fatty liver disease depending on angiotensin II type 1 receptor (A1166C) gene polymorphism. Materials and methods.
O. Ya. Babak, M. M. Zaitseva
doaj   +1 more source

Renin-Angiotensin A1166C Polymorphism and the Rrisk of Stroke [PDF]

open access: yesJournal of Cell and Molecular Research, 2015
Stroke is the leading cause of death and disability in the world after the cancer and cardiovascular diseases. Genetic factors have main significance to got stroke.
Peyman Zargari   +8 more
doaj   +1 more source

Hypertension regulating angiotensin peptides in the pathobiology of cardiovascular disease

open access: yesClinical and Experimental Hypertension, 2018
Renin angiotensin system (RAS) is an endogenous hormone system involved in the control of blood pressure and fluid volume. Dysregulation of RAS has a pathological role in causing cardiovascular diseases through hypertension.
Misbah Hussain, Fazli Rabbi Awan
doaj   +1 more source

Home - About - Disclaimer - Privacy