Results 261 to 270 of about 134,000 (307)

Angiotensinogen gene (met235thr and thr174met), angiotensin-converting enzyme (intron 16 insertion/deletion) and angiotensin II type 1 receptor (A1166C) gene polymorphisms in patients with pre-eclampsia

Shamaila Habib, Maryam Zafar, Osheen Sajjad, Ali Ammar, Saqib Mahmood   +4 more
openalex   +2 more sources

Algorithms in Allergy: Hereditary Angioedema

Allergy, EarlyView.
Konrad Bork, Markus Magerl, Emel Aygören‐Pürsün, Henriette Farkas   +3 more
wiley   +1 more source

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Angiotensin (1???7) is an antagonist at the type 1 angiotensin II receptor

Journal of Hypertension, 1994
The present study investigated the antagonism of the amino-terminal heptapeptide fragment of angiotensin II ([des-Phe8]-angiotensin II; Ang(1-7)) to angiotensin II (Ang II) both in vitro in rabbit aortae and in vivo in rats.In rabbit isolated endothelium intact aortic rings Ang(1-7) caused a concentration-related rightward displacement of the Ang II ...
J M, Mahon, R D, Carr, A K, Nicol, I W, Henderson   +3 more
openaire   +2 more sources

Biased Agonism of the Angiotensin II Type 1 Receptor

Mini-Reviews in Medicinal Chemistry, 2012
G protein-coupled receptors (GPCRs) can be activated by multiple ligands and exhibit the capacity to couple to numerous intracellular signal transduction pathways. This property allows GPCRs to be modulated by biased agonists that selectively activate specific subsets of GPCR-regulated cellular signaling proteins.
C M, Godin, S S G, Ferguson
openaire   +2 more sources

Type 1 angiotensin II receptors of adrenal tumors

Steroids, 1995
The present study was designed to clarify the transcriptional regulation of the human type 1 angiotensin II receptor (AT1) gene and its pathophysiological roles in steroidogenesis by adrenal tumors. A cDNA encoding type 1 angiotensin II receptor (AT1) was isolated from a human liver cDNA library encoding a protein of 359 amino acids with seven ...
H, Nawata, R, Takayanagi, K, Ohnaka, Y, Sakai, K, Imasaki, T, Yanase, S, Ikuyama, S, Tanaka, K, Ohe   +8 more
openaire   +2 more sources

Expression of type 1 angiotensin II receptors in human aldosteronomas

Endocrine Research, 1995
Type 1 angiotensin II (AII) receptors (AT1 receptors), besides stimulation of aldosterone secretion, seem to transduce the growth factor-like activity of AII on glomerulosa cells. Although a local renin-angiotensin system and AII synthesis have been found in human adrenals and aldosteronomas, it is unclear whether aldosteronomas express AT1 receptors ...
R. SARZANI, OPOCHER, GIUSEPPE, P. DESSIFULGHERI, V. PACI, G. COLA, S. ROCCO, B. VIANELLO, MANTERO, FRANCO, A. RAPPELLI   +8 more
openaire   +2 more sources

Endocytosis and signaling of angiotensin II type 1 receptor

2023
A vasoactive octapeptide angiotensin II (Ang II) hormone is the key regulator of the renin-angiotensin system (RAS). It binds with the two different plasma membrane receptors like angiotensin II type 1 (AT1) and type 2 (AT2) and consequence various biological responses occur. Further, AT1 has two subtypes such as AT1A and AT1B.
openaire   +2 more sources

Gene Polymorphism of Angiotensin II Type 1 and Type 2 Receptors

Current Pharmaceutical Design, 2013
Renin-angiotensin system (RAS) plays a key role in pathogenesis of cardiovascular disease and in the responsiveness for various types of medications. A large number of genetic investigations have been carried out to examine the association between gene variants of RAS and predisposition to cardiovascular diseases, such as hypertension, coronary artery ...
Tomohiro, Katsuya, Ryuichi, Morishita
openaire   +2 more sources

The distribution of angiotensin II type 1 receptors, and the tissue renin-angiotensin systems

Molecular Medicine Today, 1995
Since its discovery, the functions of the renin-angiotensin system (RAS) have attracted a great deal of attention, and the roles it plays under normal conditions, and in disease, acquire a deepening significance with every year. In general, the RAS has been considered largely in terms of its roles in sodium and potassium homeostasis and the regulation ...
G P, Vinson, M M, Ho, J R, Puddefoot
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Type 1 angiotensin II receptors in rat and human sperm

Journal of Endocrinology, 1995
Abstract The physiological factors which induce and maintain mammalian sperm maturation and motility generally remain unclear, although several agents are known to be involved. We describe here the application of immunocytochemical and immunoblotting methods to identify the angiotensin II type 1 (AT1) receptor in the tails of ejaculated rat and
G P, Vinson, J R, Puddefoot, M M, Ho, S, Barker, J, Mehta, E, Saridogan, O, Djahanbakhch   +6 more
openaire   +2 more sources