Results 61 to 70 of about 126,669 (262)
Annals of Gastroenterological Surgery, EarlyView.This retrospective study explored the potential impact of renin–angiotensin system inhibitors (RASIs) on renal function during the ileostomy period in patients undergoing rectal cancer surgery. RASI use was associated with early postoperative renal impairment, and relatively slow recovery of renal function was observed until stoma closure.
Yusaku Shogen +6 more
wiley +1 more source
Respiratory virus mRNA vaccines: mRNA Design, clinical studies, and future challenges
Animal Models and Experimental Medicine, EarlyView.Abstract Respiratory infectious diseases frequently erupt on a global scale, with RNA viruses, such as SARS‐CoV‐2, RSV, and influenza viruses, posing challenges to vaccine development due to their high mutation rates. Traditional vaccine development cycles are lengthy and struggle to keep pace with rapidly evolving viruses, whereas messenger RNA (mRNA)
Linlin Zheng, Han Feng
wiley +1 more source
The Effect of Endogenous Angiotensin II on Alveolar Fluid Clearance in Rats with Acute Lung Injury
Canadian Respiratory Journal, 2012 BACKGROUND: In acute lung injury (ALI), angiotensin II (Ang II) plays a vital role in the stimulation of pulmonary permeability edema formation through the angiotensin type 1 (AT1) receptor.
Jia Deng +4 more
doaj +1 more source
Animal models of hypertension and concurrent organs injury
Animal Models and Experimental Medicine, EarlyView.Although hypertension is a frequently seen chronic condition across the world, its exact cause remains unclear. Animal models are beneficial for clarifying the pathogenic mechanism of hypertension and examining new treatments. An optimal animal model for studies on hypertension must well mimic human‐like hemodynamics and pathophysiological structural ...
Ye Wang, Xiaoliang Jiang, Zhiwei Yang
wiley +1 more source
Post-Transcriptional Control of Angiotensin II Type 1 Receptor Regulates Osteosarcoma Cell Death
Cellular Physiology and Biochemistry, 2018 Background/Aims: MicroRNAs (miRNAs) play an essential role in the tumorigenesis of osteosarcoma (OS). However, the effects of miR-1248 on chemo-resistant potential of OS have not been studied. Here, we addressed this question.
Yue Zhao, Kaicheng Xu, Peng Liu
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.In this review, the pathological, molecular, and cellular changes observed in the COVID‐19 lung are compared to those in the laboratory rat treated with monocrotaline (MCT). Similarities that reflect common changes associated with inflammation and endothelial cell dysfunction are observed in both states, leading to a lung pathology characterized by ...
Luke P. Kris +3 more
wiley +1 more source
DNA Methylation-Reprogrammed Ang II (Angiotensin II) Type 1 Receptor-Early Growth Response Gene 1-Protein Kinase C ε Axis Underlies Vascular Hypercontractility in Antenatal Hypoxic Offspring [PDF]
, 2020 Ting Xu +11 more
openalex +1 more source
Animal Models and Experimental Medicine, EarlyView.Current radiation medical countermeasures primarily focus on hematopoietic acute radiation syndrome (H‐ARS) using agents like granulocyte colony‐stimulating factor (G‐CSF), granulocyte‐macrophage colony‐stimulating factor (GM‐CSF), and romiplostim, alongside treatments for internal contamination (Prussian blue, diethylenetriamine pentaacetate [DTPA ...
Wen‐Bing Ma +12 more
wiley +1 more source
BMC NeuroscienceBackground Astrocytes are the most abundant cell type of the central nervous system and are fundamentally involved in homeostasis, neuroprotection, and synaptic plasticity.
Daniel Navin Olschewski +12 more
doaj +1 more source