Results 41 to 50 of about 134,000 (307)

Angiotensin II type 2 receptor–interacting protein 3a inhibits ovarian carcinoma metastasis via the extracellular HMGA2-mediated ERK/EMT pathway

open access: yesTumor Biology, 2017
Local migration and long-distance metastasis is the main reason for higher mortality of ovarian cancer. Microtubule-associated tumor suppressor 1/angiotensin II type 2 receptor–interacting protein is associated with tumor initiation and progression and ...
Ping Huang   +3 more
doaj   +1 more source

ANGIOTENSIN II TYPE 1 RECEPTOR AUTOANTIBODIES

open access: yesJournal of Hypertension, 2019
Objective:Primary aldosteronism (PA), the most common cause of endocrine hypertension, is a disorder due to bilateral adrenal hyperplasia (BAH) and aldosterone producing adenoma (APA), featuring concentrations of plasma aldosterone that are inappropriately high for the circulating renin levels ...
M. Piazza   +4 more
openaire   +2 more sources

Roles and functions of Atp6ap2 in the brain

open access: yesNeural Regeneration Research, 2018
The classical renin-angiotensin system (RAS) in the body has been studied intensively in the last decades, since it is known that this system is involved in the regulation of blood pressure.
Alexander Bracke   +1 more
doaj   +1 more source

Losartan improved hippocampal long‐term potentiation impairment induced by repeated LPS injection in rats

open access: yesPhysiological Reports, 2021
Cognitive impairment has been known as a common consequence of brain inflammation. Long‐term potentiation (LTP), the generally accepted cellular mechanism for memory formation in the mammalian brain, has been shown to be suppressed by inflammation ...
Mahmoud Hosseini   +2 more
doaj   +1 more source

Versatility of the Angiotensin II Type 1 Receptor [PDF]

open access: yesCirculation Research, 1998
This issue of Circulation Research includes 3 interesting studies that represent new concepts of AT1 receptor–mediated cell signaling in the cardiovascular system, which is currently of intense interest. The AT1 receptor mediates many important cardiovascular responses, including vasoconstriction, vascular and cardiac remodeling (cell proliferation ...
openaire   +1 more source

Angiotensin II type 1 receptor antagonists and their combinations in the treatment of hypertension

open access: yesSouth African Family Practice, 2012
No abstract available.
J.A. Ker
doaj   +1 more source

ANGIOTENSIN II TYPE-1 RECEPTOR (AT1R) DISTRIBUTION IN BPH, HIGH GRADE PIN AND ADENOCARCINOMA OF THE PROSTATE

open access: yesJurnal Urologi Indonesia, 2016
Objective: The aim of the study was to detect the differences in number and the distribution of angiotensin II type-1 receptor (AT1R) in BPH, high grade PIN, and adenocarcinoma of the prostate. Material & method: A prospective study was performed in RSHS,
Isdianto Septiadi   +11 more
doaj   +1 more source

Renal denervation inhibits the renin–angiotensin–aldosterone system in spontaneously hypertensive rats

open access: yesClinical and Experimental Hypertension, 2022
This study was conducted to explore the effect of renal denervation (RDN) on the renin–angiotensin–aldosterone system (RAAS) in spontaneously hypertensive rats (SHRs).
Fei Qin   +4 more
doaj   +1 more source

Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors. [PDF]

open access: yesPLoS ONE, 2014
INTRODUCTION: Recently, we could show that angiotensin II, the reactive peptide of the blood pressure-regulating renin-angiotensin-aldosterone-system, causes the formation of reactive oxygen species and DNA damage in kidneys and hearts of hypertensive ...
Susanne Brand   +4 more
doaj   +1 more source

Downregulation of Angiotensin II Type 1 Receptors During Sepsis [PDF]

open access: yesHypertension, 2001
Our study aimed to characterize the mechanisms underlying the attenuated cardiovascular responsiveness toward the renin-angiotensin system during sepsis. For this purpose, we determined the effects of experimental Gram-negative and Gram-positive sepsis in rats.
M, Bucher   +4 more
openaire   +2 more sources

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