Results 71 to 80 of about 146,093 (222)

Differential clinical profile of candesartan compared to other angiotensin receptor blockers

open access: yesVascular Health and Risk Management, 2011
Relu Cernes1,2, Margarita Mashavi1,3, Reuven Zimlichman1,31The Brunner Institute for Cardiovascular Research, Wolfson Medical Center and Tel Aviv University, Tel Aviv, Israel; 2Department of Nephrology, Wolfson Medical Center, Holon, Israel; 3Department ...
Zimlichman R
doaj  

Effects of Telmisartan and Candesartan on the Metabolism of Lipids and Glucose in Kidney Transplant Patients: A Prospective, Randomized Crossover Study

open access: yesTransplantation Direct, 2019
Background. The risk of cardiovascular events remains after kidney transplantation (KT). Abnormal glucose metabolism and hyperlipidemia contribute partly to this risk.
Yoshifumi Miura, MD   +5 more
doaj   +1 more source

Transforming growth factor-β in diabetic nephropathy

open access: yesThe Egyptian Journal of Internal Medicine, 2013
Background Renal failure is a common and serious complication of long-standing diabetes mellitus. Diabetes is the most common cause of end-stage renal failure.
Karima Y. Ahmed   +3 more
doaj   +1 more source

Suppression of Aldosterone Synthesis and Secretion by Channel Antagonists

open access: yesInternational Journal of Endocrinology, 2012
Aldosterone, a specific mineralocorticoid receptor (MR) agonist and a key player in the development of hypertension, is synthesized as a final product of renin-angiotensin-aldosterone system.
Keiichi Ikeda   +4 more
doaj   +1 more source

New Angiotensin II Type 1 Receptor Blocker, Azilsartan, Attenuates Cardiac Remodeling after Myocardial Infarction

open access: yesBiological and Pharmaceutical Bulletin, 2013
After an acute myocardial infarction (MI), neurohumoral systems including renin-angiotensin-aldosterone system (RAAS) are activated which in turn aggravate cardiac remodeling. Angiotensin receptor blockers (ARBs) are useful drugs for suppression of RAAS. The purpose of this study was to evaluate a new ARB, azilsartan, for suppressing cardiac remodeling
Yuichi, Nakamura   +3 more
openaire   +3 more sources

Inhibition of RAS in diabetic nephropathy

open access: yesInternational Journal of Nephrology and Renovascular Disease, 2015
Rabi Yacoub, Kirk N Campbell Department of Medicine, Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, NY, USA Abstract: Diabetic kidney disease (DKD) is a progressive proteinuric renal disorder in patients with type 1 or type 2
Yacoub R, Campbell KN
doaj  

New Approaches to Blockade of the Renin–Angiotensin–Aldosterone System: Characteristics and Usefulness of the Direct Renin Inhibitor Aliskiren

open access: yesJournal of Pharmacological Sciences, 2010
Since renin inhibition interferes with the first and rate-limiting steps in the renin–angiotensin system, the renin step is a very attractive target for lowering blood pressure and minimizing target-organ damage.
Atsuhiro Ichihara   +6 more
doaj   +1 more source

Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension

open access: yesEmerging Microbes and Infections, 2020
The dysfunction of the renin-angiotensin system (RAS) has been observed in coronavirus infection disease (COVID-19) patients, but whether RAS inhibitors, such as angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II type 1 receptor blockers
Juan Meng   +12 more
doaj   +1 more source

Association between chronic ACE inhibitor exposure and decreased odds of severe disease in patients with COVID-19

open access: yesAnatolian Journal of Cardiology, 2020
Objective: Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Renin-angiotensin-aldosterone-system (RAAS) inhibitors may increase the expression of angiotensin-converting enzyme 2, which is ...
Naci Şenkal   +5 more
doaj   +1 more source

Pharmacotherapeutic Analysis and Prescription Pattern of Antihypertensive Drugs Dispensed at Community Pharmacies in Palestine [PDF]

open access: yesمجلة جامعة النجاح للأبحاث العلوم الطبيعية, 2003
The objective of this study is to explore the influence of current therapeutic recommendations on the prescribing trends of anti-hypertensive drugs in general medical practice in Palestine.
doaj   +1 more source

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