Results 111 to 120 of about 134,775 (304)

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Telmisartan reduces systemic inflammation and alters the renin-angiotensin system in mild COVID-19

Scientific Reports
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19, a respiratory viral infection that disrupts renin angiotensin system (RAS) peptide metabolism by downregulating angiotensin converting enzyme-II (ACE2), leading to accumulation
Angela Lu, Melissa Agsalda-Garcia, Weiyuan Hu, Catherine Chester, Aditya Anil Naik, Brooks I. Mitchell, Isaac Asante, Scott A. Souza, Kuo-Chiang Lian, Zao Zhang, Hannah V. Schmitz, Malia L. Ramirez, Richa Varshney, Serena DelMundo, Dominic C. Chow, Cecilia M. Shikuma, Stan G. Louie   +16 more
doaj   +1 more source

The vascular renin-angiotensin-aldosterone system

, 2001
PhDThe renin-angiotensin-aldosterone system (RAAS) is one of the major regulators of blood pressure. The actions and generation of RAAS components at the tissue level are less well appreciated.
Xiao, Fang
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Expert Perspectives: Defining and Managing Progressive Pulmonary Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Systemic sclerosis–associated interstitial lung disease (SSc‐ILD) is one of the leading causes of morbidity and mortality in SSc, affecting up to three‐quarters of patients. The disease course is highly heterogeneous, ranging from indolent, nonprogressive forms to rapidly progressive pulmonary fibrosis (PPF).
Devis Benfaremo, Dinesh Khanna, Corrado Campochiaro, Vincent Cottin, Fabrizio Luppi, Marco Matucci‐Cerinic, Gianluca Moroncini, Yannick Allanore   +7 more
wiley   +1 more source

Roles of Brain Angiotensin II in Cognitive Function and Dementia

International Journal of Hypertension, 2012
The brain renin-angiotensin system (RAS) has been highlighted as having a pathological role in stroke, dementia, and neurodegenerative disease. Particularly, in dementia, epidemiological studies indicate a preventive effect of RAS blockade on cognitive ...
Masaki Mogi, Jun Iwanami, Masatsugu Horiuchi   +2 more
doaj   +1 more source

Local angiotensin II promotes adipogenic differentiation of human adipose tissue mesenchymal stem cells through type 2 angiotensin receptor

Stem Cell Research, 2017
Obesity is often associated with high systemic and local activity of renin-angiotensin system (RAS). Mesenchymal stem cells of adipose tissue are the main source of adipocytes.
Veronika Y. Sysoeva, Liudmila V. Ageeva, Pyotr A. Tyurin-Kuzmin, George V. Sharonov, Daniyar T. Dyikanov, Natalia I. Kalinina, Vsevolod A. Tkachuk   +6 more
doaj   +1 more source

Expression of angiotensin II type 1 receptor in rat bladder smooth muscle cells in response to a streptzotocin induced diabetes mellitus model [PDF]

, 2012
Introduction: The aim of this study was to investigate angiotensin II type 1 (AT1) receptors in rat bladder smooth muscle cells and alterations of AT1 receptors by diabetes mellitus and diuretic states.
Tobu, Shohei, Matsuo, Manabu, Mori, Ken-ichi, Sakai, Hideki, Hatada, Teppei, Noguchi, Mitsuru   +5 more
core   +1 more source

Beyond right or wrong: How partial credit scoring on multiple‐choice questions improves student performance and assessment perceptions

British Journal of Clinical Pharmacology, EarlyView.
Aims In this study, we examined the effects of assigning partial credit to selected answer choices on student performance and perceptions in a pharmacology course using Type A multiple‐choice questions (MCQs). Methods Partial credit scoring was incorporated into quizzes and exams in a 10‐week pharmacology course for postbaccalaureate premedical ...
Stephen D. Schneid, Chris Armour, Katharina Brandl   +2 more
wiley   +1 more source

Novel Antihypertensive Medications to Target the Renin-Angiotensin System: Mechanisms and Research

Reviews in Cardiovascular Medicine
An estimated 1.28 billion individuals in the global population suffer from hypertension. Importantly, uncontrolled hypertension is strongly linked to various cardiovascular and cerebrovascular diseases.
Zhe Jiang, Changlin Zhai, Guanmin Tang
doaj   +1 more source

Envolvimento da angiotensina II nos eventos iniciais da sepse avaliado através de parâmetros hemodinâmicos e inflamatórios [PDF]

, 2009
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia.A sepse consiste em uma síndrome de resposta inflamatória sistêmica secundária à infecção. A angiotensina II além de
Pacheco, Letícia Kramer
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