Results 91 to 100 of about 74,786 (193)

The role of glucose transporter 4 during cognitive enhancement by Angiotensin IV

, 2014
Alzheimer\u27s disease (AD) is a progressive neurodegenerative disorder, characterized behaviorally by profound cognitive impairment. Currently, there is no cure for this disorder and available therapeutics only slow the progression of cognitive decline ...
Sandusky, Leslie Ann
core   +2 more sources

A possible correlation between oxytocin-induced and angiotensin IV-induced anti-hyperalgesia at the spinal level in rats

, 2012
[[abstract]]In our previous study, we showed that intrathecal (i.t.) administration of angiotensin IV (Ang IV), an insulin-regulated aminopeptidase (IRAP) inhibitor, attenuated inflammatory hyperalgesia in rats.
Chow, LH;Tao, PL;Chen, JC;Liao, RM;Chang, EP;Huang, EYK
core   +1 more source

Chronic production of angiotensin IV in the brain leads to hypertension that is reversible with an angiotensin II AT1 receptor antagonist

, 2004
Angiotensin IV (Ang IV) is a metabolite of the potent vasoconstrictor angiotensin II (Ang II). Because specific binding sites for this peptide have been reported in numerous tissues including the brain, it has been suggested that a specific Ang IV ...
Touyz, R.M., Reudelhuber, T.L., Thibault, G., Silversides, D.W., Lochard, N.   +4 more
core   +1 more source

Up regulation of AT4 receptor levels in carotid arteries following balloon injury

, 1999
Angiotensin IV, (V-Y-I-H-P-F), binds to AT receptors in blood vessels to induce vasodilatation and proliferation of cultured bovine endothelial cells.
Mendelsohn, Frederick A.O., Bingley, John A., Chai, Siew-Yeen, Fennessy, Paul A., Clune, Eleanor F., Moeller, Ingrid, Albiston, Anthony L.   +6 more
core   +1 more source

Effects of angiotensin II and its metabolites in the rat coronary vascular bed: Is angiotensin III the preferred ligand of the angiotensin AT(2) receptor?

, 2008
Aminopeptidases metabolize angiotensin II to angiotensin-(2-8) (=angiotensin III) and angiotensin-(3-8) (=angiotensin IV), and carboxypeptidases generate angiotensin-(1-7) from angiotensin I and II.
Batenburg, Wendy, Esch, Joep, Oosterveer, Diana, van Veghel, Richard, Danser, Jan   +4 more
core   +1 more source

Astragaloside IV Attenuates Angiotensin II-Induced Inflammatory Responses in Endothelial Cells: Involvement of Mitochondria

Journal of Inflammation Research
Shiyu Zhang, Shijie Li, Lin Cui, Shiyang Xie, Youping Wang Division of Cardiology and Central Laboratory, First Affiliated Hospital, Henan University of Traditional Chinese Medicine, Zhengzhou, 450000, People’s Republic of ChinaCorrespondence: Youping ...
Zhang S, Li S, Cui L, Xie S, Wang Y
doaj  

Angiotensin IV suppresses inflammation in the brains of rats with chronic cerebral hypoperfusion. [PDF]

J Renin Angiotensin Aldosterone Syst, 2018
Wang QG, Xue X, Yang Y, Gong PY, Jiang T, Zhang YD.   +5 more
europepmc   +1 more source

The Effect of Angiotensin IV on Plasminogen Activator Inhibitor-1 Expression in Rat Mesangial Cells Cultured in High Glucose

, 2008
Angiotensin II (Ang II) contributes to the development of diabetic glomerulosclerosis by increasing glomerular plasminogen activator inhibitor-1 (PAI-1) expression.
馬場園,　哲也, 岩本,　安彦, 坊内,　良太郎, 村田,　秀一   +3 more
core  

Design and Synthesis of Angiotensin IV Peptidomimetics Targeting the Insulin-Regulated Aminopeptidase (IRAP)

, 2010
Peptidomimetics derived from the bioactive hexapeptide angiotensin IV (Ang IV, Val1-Tyr2-Ile3-His4-Pro5-Phe6) have been designed and synthesized. These peptidomimetics are aimed at inhibiting the insulin-regulated amino peptidase (IRAP), also known as ...
Andersson, Hanna
core  

Retraction notice to "The Procognitive and Synaptogenic Effects of Angiotensin IV-Derived Peptides Are Dependent on Activation of the Hepatocyte Growth Factor/c-Met System" [J Pharmacol Exp Ther 351 (2014) 390-402]. [PDF]

J Pharmacol Exp Ther
Benoist CC, Kawas LH, Zhu M, Tyson KA, Stillmaker L, Appleyard SM, Wright JW, Wayman GA, Harding JW.   +8 more
europepmc   +1 more source