Results 81 to 90 of about 74,786 (193)

The Hepatocyte Growth Factor/c-Met Antagonist, Divalinal-Angiotensin IV, Blocks the Acquisition of Methamphetamine Dependent Conditioned Place Preference in Rats [PDF]

, 2012
The use of methamphetamine (MA) is increasing in the U.S. and elsewhere around the world. MA’s capacity to cause addiction significantly exceeds other psychostimulant drugs, and its use negatively impacts learning and memory. Recently, attempts have been
Wendy L. Wilson, Kawas, Leen, Wright, John W, Audrey Jensen, Leen Kawas, John W. Wright, Alan S. Boydstun, Vanessa Wakeling, Wakeling, Vanessa, Jensen, Audrey, Boydstun, Alan S, Harding, Joseph W, Wilson, Wendy L, Joseph W. Harding   +13 more
core   +1 more source

Physiopathology of the Brain Renin-Angiotensin System

Life
The renin-angiotensin system (RAS) has evolved from being considered solely a peripheral endocrine system for cardiovascular control to being recognized as a complex molecular network with important functions in the central nervous system (CNS) and ...
Cristina Cueto-Ureña, María Jesús Ramírez-Expósito, María Pilar Carrera-González, José Manuel Martínez-Martos   +3 more
doaj   +1 more source

Thyroid Disorders Change the Pattern of Response of Angiotensinase Activities in the Hypothalamus-Pituitary-Adrenal Axis of Male Rats

Frontiers in Endocrinology, 2018
Thyroid disorders affect the hypothalamic-pituitary-adrenal axis with important consequences on the cardiovascular function in which the renin-angiotensin system plays a major role.
Ana B. Segarra, Isabel Prieto, Magdalena Martínez-Cañamero, Marc de Gasparo, Juan de Dios Luna, Manuel Ramírez-Sánchez   +5 more
doaj   +1 more source

Astragaloside IV inhibits angiotensin II-induced atrial fibrosis and atrial fibrillation by SIRT1/PGC-1α/FNDC5 pathway

Heliyon
Aims and objectives: Astragaloside IV (AS-IV) has been found to possess anti-oxidative, anti-inflammatory, and anti-apoptotic properties, but its effect on atrial fibrosis is yet to be determined.
Xinpeng Cong, Xi Zhu, Xiaogang Zhang, Zhongping Ning   +3 more
doaj   +1 more source

The Angiotensin II Type 2 Receptor in Brain Functions: An Update

International Journal of Hypertension, 2012
Angiotensin II (Ang II) is the main active product of the renin-angiotensin system (RAS), mediating its action via two major receptors, namely, the Ang II type 1 (AT1) receptor and the type 2 (AT2) receptor.
Marie-Odile Guimond, Nicole Gallo-Payet
doaj   +1 more source

Disulfide Cyclized Tripeptide Analogues of Angiotensin IV as Potent and Selective Inhibitors of Insulin-Regulated Aminopeptidase (IRAP)

, 2016
The insulin-regulated aminopeptidase (IRAP) localized in areas of the brain associated with memory and learning is emerging as a new promising therapeutic target for the treatment of memory dysfunctions.
Hanna Andersson (1408987), Mathias Hallberg (1656958), Anders Karlén (1281249), Gunnar Lindeberg (492163), Anders Hallberg (585061), Heidi Demaegdt (470499), Georges Vauquelin (2136157), Máté Erdélyi (1364241)   +7 more
core   +1 more source

Effect of amlodipine on the circulating renin‐angiotensin‐aldosterone system in healthy cats

Journal of Veterinary Internal Medicine
Background Systemic hypertension (SH) is a common cardiovascular disease in older cats that is treated primarily with the calcium channel blocker amlodipine besylate (AML).
Tatiana M. Garcia Marrero, Jessica L. Ward, Melissa A. Tropf, Agnes Bourgois‐Mochel, Emilie Guillot, Oliver Domenig, Lingnan Yuan, Debosmita Kundu, Jonathan P. Mochel   +8 more
doaj   +1 more source

Disulfide Cyclized Tripeptide Analogues of Angiotensin IV as Potent and Selective Inhibitors of Insulin-Regulated Aminopeptidase (IRAP)

, 2010
The insulin-regulated aminopeptidase (IRAP) localized in areas of the brain associated with memory and learning is emerging as a new promising therapeutic target for the treatment of memory dysfunctions.
Karlén, Anders,, Lindeberg, Gunnar,, Anders Hallberg, Hallberg, Mathias,, Heidi Demaegdt, Georges Vauquelin, Hallberg, Anders,, Gunnar Lindeberg, Andersson, Hanna,, Erdélyi, Máté, Hanna Andersson, Vauquelin, Georges,, Mathias Hallberg, Máté Erdélyi, Anders Karlén, Demaegdt, Heidi,   +15 more
core   +1 more source

Angiotensin IV binding site - The AT4 receptor or insulin regulated aminopeptidase (IRAP)

, 2007
Angiotensin IV (Ang IV) is a hexapeptide fragment corresponding to amino acids 3-8 (VYIHPF) of angiotensin II (Ang II) that is formed by consecutive actions of aminopeptidase A and aminopeptidase N (1) (Fig. 1).
S CHAI (19974987), F Mendelsohn (13733029), Trisha Jenkins (18031216), Anthony Albiston (19974984)   +3 more
core  

Angiotensin IV stimulates plasminogen activator inhibitor-1 expression in proximal tubular epithelial cells

, 1999
Angiotensin IV stimulates plasminogen activator inhibitor-1 expression in proximal tubular epithelial cells.BackgroundAngiotensin II (Ang II) has been shown to be implicated in the development of renal fibrosis in several forms of chronic ...
Monno, Raffaella, Schena, Francesco Paolo, Gesualdo, Loreto, Ranieri, Elena, Grandaliano, Giuseppe, Cerullo, Giuseppina, Colucci, Mario, Rossiello, Maria Rosaria, Semeraro, Nicola   +8 more
core   +1 more source