Results 11 to 20 of about 444,347 (295)
Monte Carlo optimization based QSAR modeling of angiotensin II receptor antagonists
Acta Chimica Slovenica, 2023 The pathogenesis of essential hypertension, congestive heart failure, and reno-vascular hypertension is related to angiotensin II. This study presents QSAR modeling for a set of compounds acting as angiotensin II receptor antagonists based on the Monte ...
Nemanja Nikolić +7 more
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Journal of Pharmacological Sciences, 2010 The present study was designed to examine the binding affinity and functional potency of selective angiotensin II type 1 (AT1)-receptor antagonists towards specific mutants of AT1 receptor using site-directed mutagenesis.
Mohiuddin Ahmed Bhuiyan +4 more
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Journal of Pharmacological Sciences, 2010 Based on radioligand binding and signal transduction assays in our previous study, we have determined the binding pattern and functional efficacy of the constitutively active mutant N111G of angiotensin II type 1 (AT1) receptor.
Mohiuddin Ahmed Bhuiyan +4 more
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Український Журнал Нефрології та Діалізу, 2014 Damage of renal function and dynamics of dyslipidemia in patients with type 2 diabetes mellitus with insufficient glycemic compensation under condition of correction of hypertension with angiotensin II receptor antagonists Introduction.
N.O. Pertseva
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ANGIOTENSIN RECEPTOR ANTAGONISTS: GOING WITH THE TIMES
Кардиоваскулярная терапия и профилактика, 2013 This literature review focuses on the angiotensin II receptor antagonists as one of the new and promising classes of antihypertensive medications. Apart from their antihypertensive activity, these agents possess a number of other beneficial effects.
E. O. Taratukhin
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Mineralocorticoid receptor antagonists and kidney diseases: pathophysiological basis.
Kidney International, 2019 Chronic kidney disease (CKD) represents a global health concern, and its prevalence is increasing. The ultimate therapeutic option for CKD is kidney transplantation. However, the use of drugs that target specific pathways to delay or halt CKD progression,
J. Barrera-Chimal, S. Girerd, F. Jaisser
semanticscholar +1 more source
PATIENT WITH CHRONIC HEART FAILURE. RATIONAL CHOICE OF THERAPY
Рациональная фармакотерапия в кардиологии, 2017 The theory of chronic hyperactivation of neurohormonal systems, in particular, sympathoadrenal and renin-angiotensin-aldosterone, is the basis of modern concepts of the pathogenesis of heart failure. The medicinal blocking of these two systems has proved
O. M. Drapkina, D. U. Akasheva
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Nonpeptide angiotensin II-receptor antagonists.
Japanese Journal of Pharmacology, 1994 The renin-angiotensin system (RAS) is known to play a very important role in cardiovascular diseases. The present state of the research on orally active nonpeptide angiotensin II (A II)-receptor antagonists and their pharmacological characterization will be reviewed.
Y, Inada +3 more
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Long-Term Consequences of Fetal Angiotensin II Receptor Antagonist Exposure
Case Reports in Pediatrics, 2018 Fetal angiotensin II receptor antagonist exposure is associated with major complications and even death when administered during pregnancy. Neonates frequently require intensive care treatment, and mortality is high.
K. Wegleiter +4 more
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CARDIAC GLYCOSIDES IN UP-TO-DATE CLINICAL PRACTICE
Alʹmanah Kliničeskoj Mediciny, 2016 The article reviews the use of cardiac glycosides in patients with chronic heart failure, paroxysmal tachyarrhythmia and chronic atrial fibrillation (rate control).
M. A. Gurevich, A. A. Gavrilin
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