Results 51 to 60 of about 80,027 (384)
SARS-CoV-2 mortality in blacks and temperature-sensitivity to an angiotensin-2 receptor blocker [PDF]
arXiv, 2020 Tropical climates provoke adaptations in skin pigmentation and in mechanisms controlling the volume, salt-content and pressure of body fluids. For many whose distant ancestors moved to temperate climes, these adaptations proved harmful: pigmentation decreased by natural selection and susceptibility to hypertension emerged.
arxiv
Особенности использования антигипертензивных препаратов у больных сахарным диабетом [PDF]
, 2004 In this article the modern data about pharmaceuticals drugs that used for treatment of patients with arterial hypertension and diabetes mellitus are submitted.
Rachynskyi, Ivan Danylovych +3 more
core
Advanced Biology, EarlyView.The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua +5 more
wiley +1 more source
Featuring ACE2 binding SARS-CoV and SARS-CoV-2 through a conserved evolutionary pattern of amino acid residues [PDF]
arXiv, 2020 Spike (S) glycoproteins mediate the coronavirus entry into the host cell. The S1 subunit of S-proteins contains the receptor-binding domain (RBD) that is able to recognize different host receptors, highlighting its remarkable capacity to adapt to their hosts along the viral evolution.
arxiv
Angiotensin II Receptor Subtypes and Cardiac Function [PDF]
, 2017 All the components of the renin-angiotensin system have been identified in the heart including the angiotensin II receptor subtypes AT1 and AT2 In the normal human heart, there is a decreasing receptor density from the right atrium to the left ventricle.
Brink, M. +6 more
core
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.This review highlights emerging bioengineering strategies for treating neointimal hyperplasia in the peripheral vasculature, focusing on approaches that promote re‐endothelialization, modulate smooth muscle cell phenotype, reduce inflammation, mitigate oxidative stress, and optimize biomechanical compliance.
Nikita Wilson John +5 more
wiley +1 more source
ANGIOTENSIN II RECEPTOR ANTAGONISTS AND NEPHROPROTECTION: PLACE OF OLMESARTAN
Кардиоваскулярная терапия и профилактика, 2013 The paper presents the results of experimental studies and clinical trials which demonstrate nephroprotective effects of olmesartan.
V. V. Fomin
doaj +1 more source
Mathematical model of SARS-Cov-2 propagation versus ACE2 fits COVID-19 lethality across age and sex and predicts that of SARS, supporting possible therapy [PDF]
arXiv, 2020 The fatality rate of Covid-19 escalates with age and is larger in men than women. I show that these variations correlate strongly with the level of the viral receptor protein ACE2 in rat lungs, which is consistent with the still limited and apparently contradictory data on human ACE2.
arxiv
Advanced Science, EarlyView.Overview of the regulation of intrinsic and extrinsic signals during neurodevelopment. Intrinsic genetic signals from NSCs, in conjunction with cues from microglia and blood vessels, collaboratively regulate the proliferation of NSCs, their fate determination, synaptogenesis, synaptic pruning, neuronal survival, and death, as well as communication ...
Yanyan Wang +4 more
wiley +1 more source
Expression profiles of TRPV1, TRPV4, TLR4 and ERK1/2 in the dorsal root ganglionic neurons of a cancer-induced neuropathy rat model [PDF]
Maqboul A, Elsadek B. (2018) Expression profiles of TRPV1, TRPV4,
TLR4 and ERK1/2 in the dorsal root ganglionic neurons of a cancer-induced
neuropathy rat model. PeerJ 6:e4622 https://doi.org/10.7717/peerj.4622, 2018 Background: The spread of tumors through neural routes is common in several types of cancer in which patients suffer from a moderate-to-severe neuropathy, neural damage and a distorted quality of life. Here we aim to examine the expression profiles of transient receptor potential vanilloid 1 (TRPV1) and of transient receptor potential vanilloid 4 ...
arxiv +1 more source