Analysis of the combined effect of rs699 and rs5051 on angiotensinogen expression and hypertension
Background Hypertension (HTN) involves genetic variability in the renin‐angiotensin system and influences antihypertensive response. We previously reported that angiotensinogen (AGT) messenger RNA (mRNA) is endogenously bound by miR‐122‐5p and rs699 A ...
Nicholas R. Powell +8 more
doaj +1 more source
Efficacy and safety of zilebesiran in adults with hypertension: a systematic review and meta-analysis of randomized controlled trials. [PDF]
Hussain M +9 more
europepmc +1 more source
Acute GLP-1 infusion in male adults lowers circulating angiotensin II without changing angiotensinogen, ACE, ACE2, or angiotensin-(1-7) concentrations. [PDF]
Asmar A +4 more
europepmc +1 more source
Serum Proteomic Profiling Implicates a Dysregulated Neurohormonal-Inflammatory Axis in Post-Fontan Sinus Tachycardia. [PDF]
Takaesu F +12 more
europepmc +1 more source
Chronic estrogen supplementation in the aging castrated male rat is not associated with renal injury or activation of the renin angiotensin system. [PDF]
Mallette JH +6 more
europepmc +1 more source
Linkage of the angiotensinogen gene to essential hypertension
BACKGROUND: The renin-angiotensin system is a powerful pressor system with a major influence on salt and water homeostasis. Angiotensinogen (also called renin substrate) is a key component of this system; it is cleaved by renin to yield angiotensin I ...
AJ Clark (14549150) +6 more
core
Targeting liver angiotensinogen with siRNA enhances podocyte regeneration through renin lineage cells in experimental kidney disease. [PDF]
van der Pluijm LAK +4 more
europepmc +1 more source
High Salt Intake Enhances the REVERSIR-Induced Recovery of Blood Pressure After Angiotensinogen siRNA Treatment. [PDF]
Cruz-López EO +7 more
europepmc +1 more source

