Results 91 to 100 of about 18,359 (214)

Deep learning model and omics screening highlight angiotensinogen as a 5-methylcytosine (m5C) regulated mediator of tumor-microenvironment communication in liver cancer

Frontiers in Immunology
IntroductionThe tumor microenvironment (TME) is critical for liver cancer progression and therapy response. As a key RNA modification, 5-methylcytosine (m5C) methylation is implicated in this process, yet the molecular mechanisms by which m5C ...
Huai Pang, Huai Pang, Huai Pang, Linshu Wang, Yang Li, Yuan Zhou, Yuan Zhou   +6 more
doaj   +1 more source

Amlodipine Affects Plasma Angiotensinogen Level : Indirect Evidence

, 1997
The renin-angiotensin system acts to regulate body fluid volume and blood pressure. The circulating renin substrate, angiotensinogen, secreted mainly from the liver is affected by various hormones.
Sau Kuen, Lam, Ching Teong, Chua, Ismail, Rosnah   +2 more
core   +3 more sources

Preeclampsia (PE) is a complex illness of the human gestation [PDF]

MedUNAB, 2002
Preeclampsia (PE) is a complex illness of the human gestation. It is responsible for a high perinatal morbimortality.It is the illness of the multiple theories; in one environmentaland genetic factors are associated to explain it.
Laura Gil Urbano, Juan Pablo Casas Romero, María Paula Martínez Linares, María Carolina Páez Leal, Norma Cecilia Serrano Díaz, Álvaro Andrés Navarro Mancilla   +5 more
doaj  

Sex and salt intake dependent renin-angiotensin plasticity in the liver of the rat

Endocrine Regulations, 2019
Objective. Epidemiological studies confirm that hypertensive patients respond differently to renin-angiotensin system (RAS) inhibition depending on their gender.
Pidikova Paulina, Svitok Pavel, Herichova Iveta   +2 more
doaj   +1 more source

Angiotensinogen levels and obesity in four black populations

, 1998
Background. The relationship between circulating levels of angiotensinogen and hypertension in the epidemiologic setting has not been studied much. Recent findings related to the association between hypertension and polymorphisms of the angiotensinogen ...
Ogunbiyi, Olufemi, Forrester, Terrence, Muffinda, Jacob, Cooper, Richard   +3 more
core   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

A redox switch in angiotensinogen modulates angiotensin release [PDF]

, 2010
Blood pressure is critically controlled by angiotensins, which are vasopressor peptides specifically released by the enzyme renin from the tail of angiotensinogen-a non-inhibitory member of the serpin family of protease inhibitors.
Michael P. Murphy, Penelope E. Stein, Robin W. Carrell, Zhenquan Wei, Fiona Broughton Pipkin, Randy J. Read, Yahui Yan, Aiwu Zhou, Peter L. D. Stanley   +8 more
core   +2 more sources

Angiotensinogen and C3 compete for renin-induced complement activation

Frontiers in Immunology
Renin from plasma, kidney, and recombinant sources was previously demonstrated to cleave C3 to C3a and C3b. C3a was generated at a similar rate to that by C3 convertase, and C3 cleavage was inhibited by the renin inhibitor aliskiren.
Ann-Charlotte Kristoffersson, Albin Sköld, Charlotte Welinder, Markus Wendler, Gabriella Kalliokoski, Zivile Bekassy, Diana Karpman   +6 more
doaj   +1 more source

Small Interfering RNA Therapeutics in Hypertension: A Viewpoint on Vasopressor and Vasopressor‐Sparing Strategies for Counteracting Blood Pressure Lowering by Angiotensinogen–Targeting Small Interfering RNA

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Priyanga Ranasinghe, Melisande L. Addison, David J. Webb   +2 more
doaj   +1 more source

Regulation of angiotensinogen in cerebrospinal fluid and plasma of rats

, 1983
The origin and regulation of angiotensinogen in cerebrospinal fluid (CSF) was investigated in rats by measuring renin substrate in plasma and CSF under different experimental conditions.
P. Schelling, E. Clauser, S. Muller
core   +1 more source