Results 91 to 100 of about 28,097 (222)

Local Renal Circadian Clocks Control Fluid-Electrolyte Homeostasis and BP. [PDF]

, 2014
The circadian timing system is critically involved in the maintenance of fluid and electrolyte balance and BP control. However, the role of peripheral circadian clocks in these homeostatic mechanisms remains unknown. We addressed this question in a mouse
Bonny, O., Centeno, G., Firsov, D., Gachon, F., Gomez, R.A., Jouffe, C., Maillard, M., Mordasini, D., Pradervand, S., Sequeira-Lopez, M.L., Tokonami, N.   +10 more
core   +1 more source

Evidence of Augmented Intrarenal Angiotensinogen Associated With Glomerular Swelling in Gestational Hypertension and Preeclampsia: Clinical Implications

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background AGT (angiotensinogen) synthesis occurs in renal proximal tubular epithelial cells, independent from systemic AGT, as a component of the intrarenal renin–angiotensin system.
Hiten D. Mistry, Lesia O. Kurlak, David S. Gardner, Ole Torffvit, Alastair Hansen, Fiona Broughton Pipkin, Helena Strevens   +6 more
doaj   +1 more source

RPB4 and pathogenesis of diabetes [PDF]

, 2007
Obesity is an important risk factor for a number of chronic diseases that impose a huge burden on individuals and society. Recently it has become clear that adipose tissue-secreted products may play a significant role in mediating many obesity-related ...
Kumar, Sudhesh, McTernan, P. G. (Philip G.)   +1 more
core   +1 more source

AGT May Serve as a Prognostic Biomarker and Correlated with Immune Infiltration in Gastric Cancer

International Journal of General Medicine, 2022
Fanqi Wu,1,* Longguo Zhang,2,* Li Wang,3,* Dekui Zhang4 1Department of Respiratory, Lanzhou University Second Hospital, Lanzhou, Gansu Province, People’s Republic of China; 2The Second Clinical Medical School, Lanzhou University, Lanzhou ...
Wu F, Zhang L, Wang L, Zhang D
doaj  

Hypertension: Renin-Angiotensin-Aldosterone System Alterations [PDF]

, 2015
Blockers of the renin-angiotensin-aldosterone system (RAAS), that is, renin inhibitors, angiotensin (Ang)-converting enzyme (ACE) inhibitors, Ang II type 1 receptor antagonists, and mineralocorticoid receptor antagonists, are a cornerstone in the ...
Danser, A.H.J. (Jan), Esch, J.H.M. (Joep) van, Meiracker, A.H. (Anton) van den, Riet, L. (Luuk) te, Roks, A.J.M. (Anton)   +4 more
core   +1 more source

Renin–angiotensin system gene polymorphisms and endometrial cancer

Endocrine Connections, 2016
Endometrial cancer (EC) is the most common gynaecological malignancy and its incidence is increasing. Dysregulation of the endometrial renin–angiotensin system (RAS) could predispose to EC; therefore, we studied the prevalence of RAS single nucleotide ...
Kirsty G Pringle, Sarah J Delforce, Yu Wang, Katie A Ashton, Anthony Proietto, Geoffrey Otton, C Caroline Blackwell, Rodney J Scott, Eugenie R Lumbers   +8 more
doaj   +1 more source

Effects of regular, glulisine, and aspart insulin on vascular endothelial growth factor and angiotensinogen expression in hyperglycemic retinal pigment epithelial (RPE) and human retinal endothelial cells (HRECs)

Frontiers in Ophthalmology
IntroductionDiabetic retinopathy (DR) is a leading cause of vision loss and is primarily driven by chronic hyperglycemia, which induces retinal vascular damage through mechanisms involving vascular endothelial growth factor (VEGF) and the renin ...
Fatemeh Sanie-Jahromi, Abtin Khosravi, Hooman Hadianfard, M. Hossein Nowroozzadeh   +3 more
doaj   +1 more source

Polymorphism of RAAS genes in patients with COVID-19: comparison with frequency in population and relationship with severity of course [PDF]

Терапевтический архив
Aim. Evaluation of genes polymorphisms frequencies of angiotensinogen (AGT), angiotensin converting enzyme type 1 (ACE1) and angiotensin II receptors type 1 (AGTR1) and type 2 (AGTR2) in patients admitted with coronavirus disease (COVID-19) and its ...
Anna E. Bragina, Yulia N. Rodionova, Ekaterina S. Ogibenina, Alexander S. Fomin, Valery I. Podzolkov   +4 more
doaj   +1 more source

Angiotensin production by the heart: a quantitative study in pigs with the use of radiolabeled angiotensin infusions [PDF]

, 1998
BACKGROUND: Beneficial effects of ACE inhibitors on the heart may be mediated by decreased cardiac angiotensin II (Ang II) production.
Danser, A.H.J. (Jan), Kats, J.P. (Sjors) van, Meegen, J.R. (Jan) van, Sassen, L.M. (Loes), Schalekamp, M.A.D.H. (Maarten), Verdouw, P.D. (Pieter)   +5 more
core  

Small Interfering RNA Therapeutics in Hypertension: A Viewpoint on Vasopressor and Vasopressor‐Sparing Strategies for Counteracting Blood Pressure Lowering by Angiotensinogen–Targeting Small Interfering RNA

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Priyanga Ranasinghe, Melisande L. Addison, David J. Webb   +2 more
doaj   +1 more source