Results 81 to 90 of about 18,359 (214)

Effect of race, genetic population structure, and genetic models in two-locus association studies: clustering of functional renin-angiotensin system gene variants in hypertension association studies

Brazilian Journal of Medical and Biological Research, 2001
Previous genetic association studies have overlooked the potential for biased results when analyzing different population structures in ethnically diverse populations.
A.C. Pereira, G.A. Mota, I. Benseñor, P.A. Lotufo, J.E. Krieger   +4 more
doaj   +1 more source

Upregulation of the Renin–Angiotensin System Is Associated with Patient Survival and the Tumour Microenvironment in Glioblastoma

Cells
Glioblastoma is a highly aggressive disease with poor survival outcomes. An emerging body of literature links the role of the renin–angiotensin system (RAS), well-known for its function in the cardiovascular system, to the progression of cancers.
Mathew Lozinski, Eugenie R. Lumbers, Nikola A. Bowden, Jennifer H. Martin, Michael F. Fay, Kirsty G. Pringle, Paul A. Tooney   +6 more
doaj   +1 more source

Isoflavones Inhibit Hydrogen Peroxide-Induced Angiotensinogen Secretion

The renin–angiotensin system helps regulate the endocrine system in modulating blood pressure, fluid volume, and body fluid electrolyte levels. The disruption of the renin–angiotensin system can lead to kidney disease onset and progression ...
Mau Ogiwara, Hiyori Kato, Hinano Urushibata, Shiho Ono, Tamami Iwamoto, Shieri Inoue, Masumi Kamiyama, Haruna Adachi, Madoka Ishikawa, Miho Iwata   +9 more
core   +1 more source

Total angiotensinogen plasma level is the sum of the plasma levels of the oxidized and reduced forms of angiotensinogen.

, 2015
Total angiotensinogen plasma level is the sum of the plasma levels of the oxidized and reduced forms of angiotensinogen.
Mansureh Entezar-E-Ghaem (789107), Soheila Rahgozar (789104), Bill Giannakopoulos (789111), Miao Qi (665154), Steven A. Krilis (789110), Tayebeh Amirian (789105), Zahra Shahshahan (789106), Hatav Ghasemi Tehrani (789108), Mehran Miroliaei (789109)   +8 more
core   +1 more source

Location and secretion of brain angiotensinogen

, 1995
Angiotensinogen is a glycoprotein with intriguing structural similarities to the serine proteinase inhibitors but with only one known function: to act as a substrate in the enzymatic generation of angiotensin peptides.
Sernia C.
core   +1 more source

Hypertension regulating angiotensin peptides in the pathobiology of cardiovascular disease

Clinical and Experimental Hypertension, 2018
Renin angiotensin system (RAS) is an endogenous hormone system involved in the control of blood pressure and fluid volume. Dysregulation of RAS has a pathological role in causing cardiovascular diseases through hypertension.
Misbah Hussain, Fazli Rabbi Awan
doaj   +1 more source

Zilebesiran for treating hypertension; the result of recent findings [PDF]

Journal of Nephropathology
Given the pressing need for new medications with minimal adverse effects to address uncontrolled hypertension, this manuscript explores the potential of Zilebesiran as a crucial therapeutic agent. Zilebesiran is an experimental RNA interference drug that
Atefeh Saljoughian Esfahani, Yasaman Vahdani, Payam Peymani, Soha Razmjouei, Mahdieh Ahmadnia, Hadi Taghavinejad, Jyoti Baharani, Maryam Bakhshi   +7 more
doaj   +1 more source

Expression of the renin and angiotensinogen genes.

Folia Pharmacologica Japonica, 1991
Recent advances in molecular biological techniques provide us with genetic approaches for studying the renin-angiotensin system. Renin and angiotensinogen cDNAs have been cloned in several species, and the sequences are highly conserved between the species.
IWAO, Hiroshi, ABE, Youichi
openaire   +3 more sources

Angiotensinogen localization and secretion in the rat pancreas

, 2003
Renin and angiotensinogen have been previously found in the rat pancreas, and angiotensin receptors have been located in the apical domain of duct cells.
FONZI, Luciano, SERNIA, Conrad, Regoli, M., REGOLI, Marì, Fonzi, L., Bertelli, E., Bendayan, M., Sernia, C., BERTELLI, Eugenio, BENDAYAN, Moise   +9 more
core   +1 more source

Elevated angiotensinogen mRNA levels in rat liver by nephrectomy

, 1990
The expression of the angiotensinogen gene was studied in nephrectomized rats with and without adrenal glands. Angiotensinogen mRNA was measured by a sensitive radiodensitometric hybridization assay.
K. Fukui, S. Nakanishi, H. Iwao, T. Tamaki, S. Kimura, A. Nakamura, H. Ohkubo, Y. Abe   +7 more
core   +1 more source