Results 61 to 70 of about 28,097 (222)

Mistyping of Angiotensinogen M235T Alleles [PDF]

Hypertension Research, 2006
Conflicting results are to be found in the literature on the relationship between the M235T polymorphism of the angiotensinogen (AGT) gene and hypertension. The controversy may be due to insufficient numbers of subjects, the variability of the inclusion criteria and the different genotype analysis methods used.
Erzsébet, Lizanecz, Eniko T, Pásztor, Attila, Mohácsi, Zoltán, Papp, István, Edes, Attila, Tóth   +5 more
openaire   +2 more sources

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

Second Trimester Amniotic Fluid Angiotensinogen Levels Linked to Increased Fetal Birth Weight and Shorter Gestational Age in Term Pregnancies

Life
Background: Despite the considerable progress made in recent years in fetal assessment, the etiology of fetal growth disturbances is not as yet well understood.
Dionysios Vrachnis, Alexandros Fotiou, Aimilia Mantzou, Vasilios Pergialiotis, Panagiotis Antsaklis, George Valsamakis, Sofoklis Stavros, Nikolaos Machairiotis, Christos Iavazzo, Christina Kanaka-Gantenbein, George Mastorakos, Petros Drakakis, Nikolaos Vrachnis, Nikolaos Antonakopoulos   +13 more
doaj   +1 more source

Manipulation of components of the renin angiotensin system in renal proximal tubules fails to alter atherosclerosis in hypercholesterolemic mice

Frontiers in Cardiovascular Medicine, 2023
Background and objectiveWhole body manipulation of the renin-angiotensin system (RAS) consistently exerts profound effects on experimental atherosclerosis development. A deficit in the literature has been a lack of attention to the effects of sex.
Masayoshi Kukida, Naofumi Amioka, Dien Ye, Hui Chen, Jessica J. Moorleghen, Ching-Ling Liang, Deborah A. Howatt, Yuriko Katsumata, Yuriko Katsumata, Motoko Yanagita, Motoko Yanagita, Hisashi Sawada, Hisashi Sawada, Hisashi Sawada, Alan Daugherty, Alan Daugherty, Alan Daugherty, Hong S. Lu, Hong S. Lu, Hong S. Lu   +19 more
doaj   +1 more source

Angiotensin‐converting enzyme and exercise adaptations: Genetic variability, pharmacological modulation and future directions

The Journal of Physiology, EarlyView.
Abstract figure legend ACE I/D genotype, enzyme activity and integrated physiological adaptations. Upper panel: Conceptual framework linking the ACE I/D polymorphism (left) with circulating/tissue ACE activity (centre; violin plots based on hypothetical data for illustration) and strength/power versus endurance phenotypes (right).
Tórur Sjúrðarson, Nikolai B. Nordsborg   +1 more
wiley   +1 more source

A local renal renin–angiotensin system activation via renal uptake of prorenin and angiotensinogen in diabetic rats

Diabetes, Metabolic Syndrome and Obesity, 2016
Akihiro Tojo,1 Satoshi Kinugasa,1 Toshiro Fujita,2 Christopher S Wilcox3 1Division of Nephrology and Endocrinology, 2Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan; 3Division of Nephrology and Hypertension ...
Tojo A, Kinugasa S, Fujita T, Wilcox CS
doaj  

Effects of AGT and AGTR1 Genetic Polymorphisms and Changes in Blood Pressure Over a Five-Year Follow-Up

Risk Management and Healthcare Policy, 2023
Siwaphorn Chaimati,1 Prapimporn Chattranukulchai Shantavasinkul,2 Piyamitr Sritara,2 Jintana Sirivarasai3 1Doctoral Program in Nutrition, Faculty of Medicine Ramathibodi Hospital and Institute of Nutrition, Mahidol University, Bangkok, 10400, Thailand ...
Chaimati S, Shantavasinkul PC, Sritara P, Sirivarasai J   +3 more
doaj  

Differential involvement of hippocampal angiotensin 1 receptors in learning and memory processes in bulbectomized rats [PDF]

, 2016
There is conflicting evidence regarding the effect of AT1 receptor antagonists on learning and memory processes. The effects of angiotensin II and losartan administration into CA1 hippocampal area on the avoidance performance in olfactory bulbectomized ...
Belcheva, Iren, Belcheva, Stiliana, Ivanova, Margarita, Tashev, Roman   +3 more
core   +1 more source

High Sodium Intake Strengthens the Association between Angiotensinogen T174M Polymorphism and Blood Pressure Levels among Lean Men and Women: a Community-Based Study [PDF]

, 2004
Evidence on the effect of salt intake on the interaction between angiotensinogen (AGT) T174M polymorphism and high blood pressure is sparse. We therefore conducted a large population-based cross-sectional study of 2,823 men and women aged 30-74 in a ...
CUI Renzhe, ISO Hiroyasu, KUDO Minako, SHIMAMOTO Takashi, TANIGAWA Takeshi, YAMAGISHI Kazumasa, 山岸 良匡, 谷川 武   +7 more
core   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source