Results 71 to 80 of about 18,359 (214)
Physiological elevation in plasma angiotensinogen increases blood pressure
Hepatic angiotensinogen secretion is controlled by a complex pattern of physiological or pathophysiological mediators. Because plasma concentrations of angiotensinogen are close to the Michaelis-Menten constant, it was hypothesized that changes in ...
Christoph P. R. Klett, Joey P. Granger
core +1 more source
Polymorphism of RAAS genes in patients with COVID-19: comparison with frequency in population and relationship with severity of course [PDF]
Aim. Evaluation of genes polymorphisms frequencies of angiotensinogen (AGT), angiotensin converting enzyme type 1 (ACE1) and angiotensin II receptors type 1 (AGTR1) and type 2 (AGTR2) in patients admitted with coronavirus disease (COVID-19) and its ...
Anna E. Bragina +4 more
doaj +1 more source
Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib +3 more
wiley +1 more source
Metabolic pathway of angiotensinogen.
This figure shows the major metabolites of angiotensinogen, the receptors they act on and the associated enzymes. AT4 is insulin regulated membrane aminopeptidase (IRAP).
Raju Reddy (6433493) +8 more
core +1 more source
ABSTRACT Endogenous hypercortisolism (EHC) is an underrecognised and clinically significant contributor to hypertension, particularly resistant hypertension. Once viewed as a rare entity, EHC is now understood as a spectrum of cortisol excess associated with adverse cardiometabolic outcomes and target‐organ damage.
Omar Al Dhaybi, Deepak L. Bhatt
wiley +1 more source
The Serum Testosterone Level in Male Patients Is Inversely Associated With Hypertension Incidence
ABSTRACT Hypertension is a primary risk factor for cardiovascular diseases and all‐cause mortality. Testosterone, the most potent androgen in males, regulates reproduction, metabolism, and erythropoiesis. Hypertension incidence increases with age, whereas testosterone levels decline. Thus, we conducted a study to explore the association between the two
Huan‐dong Wu +5 more
wiley +1 more source
SUMMARY: OBJECTIVE Polymorphisms of the angiotensinogen (AGT ) gene, especially in the promoter region, are in linkage concordance and are associated with hypertension.
WU, SHYH-JONG;CHIANG, FU-TIEN;JIANG, JUN-RAN;HSU, KWAN-LIH;CHERN, TSER-HAW;TSENG, YUNG-ZU +1 more
core
Detection and Localization of Angiotensinogen in Cardiac Muscle [PDF]
To test the hypothesis that angiotensinogen synthesis and release will increase in neonatal left ventricular myocytes during the first few hours post-parturition, immunohistochemical techniques were applied to rat left anterior ventricular wall (LAV ...
Fitzgerald, Sullivan S.
core +3 more sources
Heart failure with preserved ejection fraction (HFpEF) is a prevalent complex syndrome characterized by diastolic dysfunction with limited therapeutic options.
Zetao Heng +7 more
doaj +1 more source
Stimulation of angiotensinogen mRNA levels in rat pituitary by estradiol
Angiotensin II (ANG II) is a putative paracrine hormone in the anterior pituitary. Angiotensinogen mRNA, however, is not detectable by Northern blot hybridization, suggesting that ANG II may not be synthesized within the pituitary.
B. S. Schachter +3 more
core +1 more source

