Results 171 to 180 of about 18,359 (214)
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Hormonal control of angiotensinogen production
Life Sciences, 1982The renin-angiotensin-aldosterone system appears to be under neural and hormonal control. Plasma angiotensinogen concentration is elevated in Cushing's disease, during pregnancy and in women taking oral contraceptives. An in vitro liver slice system was used to study the hormonal control of angiotensinogen synthesis and release in the rat ...
V J, Dzau, H C, Herrmann
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Astrocytes Synthesize Angiotensinogen in Brain
Science, 1988Cell types associated with angiotensinogen mRNA in rat brain were identified in individual brain sections by in situ hybridization with tritiated RNA probes or with a sulfur-35—labeled oligonucleotide combined with immunocytochemical detection of either glial fibrillary acidic protein (GFAP) for astrocytes or microtubule-associated protein (MAP-2) for ...
R L, Stornetta +3 more
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Journal of Neurochemistry, 1987
Abstract: Angiotensinogen (Aogen) (CA 11002–13–14), the prohormone of the neuro‐ and vasoactive peptide angioten‐ sin II (Ang II) (CA 11128–99–7), is found in dog brain as well as in dog plasma. At 2–4 μg/ml CSF, Aogen comprises 1‐ 2% of the total protein in dog CSF.
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Abstract: Angiotensinogen (Aogen) (CA 11002–13–14), the prohormone of the neuro‐ and vasoactive peptide angioten‐ sin II (Ang II) (CA 11128–99–7), is found in dog brain as well as in dog plasma. At 2–4 μg/ml CSF, Aogen comprises 1‐ 2% of the total protein in dog CSF.
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Intrarenal angiotensinogen: localization and regulation
Pediatric Nephrology, 1990Multiple lines of evidence (physiologic, immunohistochemical, and molecular biologic) support the presence of a complete intrarenal renin-angiotensin system (RAS). Localization of angiotensinogen messenger ribonucleic acid (mRNA) within the proximal tubule, together with demonstration of renin and converting enzyme mRNAs within the kidney, provide the ...
J R, Ingelfinger +6 more
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Presence of Angiotensinogen and Renin mRNAs and Angiotensinogen Protein in the Human Heart
1992The renin-angiotensin system acts to constrict vessels and enhance renal retention of sodium and water to raise the blood pressure. Angiotensinogen (ang-n) is synthesized in the liver and released into the blood. It is cut by renin, which is produced by the kidneys, and becomes angiotensin I.
Yuka Endo +9 more
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Structural Aspects of Rat Angiotensinogen
Clinical and Experimental Hypertension. Part A: Theory and Practice, 1983Rat angiotensinogen (Ao) consists of two molecular weight forms (Ao-1 and Ao-2). The amino acid composition of both forms is very similar. In addition, the immunological properties of both molecules obtained by immunodiffusion and direct radioimmunoassay are very similar as well.
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Silencing Angiotensinogen in Hypertension
New England Journal of Medicine, 2023openaire +2 more sources