Results 181 to 190 of about 28,097 (222)
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Biochemistry, 1981
Rat angiotensinogen was completely purified by a six-step procedure including (1) ammonium sulfate precipitation, (2) affinity chromatography on Affi-gel blue, (3) chromatography on DEAE-Sephacel, (4) chromatography on hydroxylapatite, (5) chromatography on Ultrogel AcA 54, and (6) isoelectric focusing.
J, Bouhnik +5 more
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Rat angiotensinogen was completely purified by a six-step procedure including (1) ammonium sulfate precipitation, (2) affinity chromatography on Affi-gel blue, (3) chromatography on DEAE-Sephacel, (4) chromatography on hydroxylapatite, (5) chromatography on Ultrogel AcA 54, and (6) isoelectric focusing.
J, Bouhnik +5 more
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Intrarenal angiotensinogen: localization and regulation
Pediatric Nephrology, 1990Multiple lines of evidence (physiologic, immunohistochemical, and molecular biologic) support the presence of a complete intrarenal renin-angiotensin system (RAS). Localization of angiotensinogen messenger ribonucleic acid (mRNA) within the proximal tubule, together with demonstration of renin and converting enzyme mRNAs within the kidney, provide the ...
J R, Ingelfinger +6 more
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Neuroendocrine Regulation of Plasma Angiotensinogen*
Endocrinology, 1991In previous studies we found that plasma angiotensinogen levels were reduced by lesions of the hypothalamic paraventricular nuclei. To determine if the decrease was caused by decreased secretion of hormones that normally stimulate angiotensinogen secretion by the liver, we correlated the changes in plasma angiotensinogen produced by paraventricular ...
T, Kjos +4 more
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Circulation, 1997
Background We evaluated the association among the M235T and T174M variants of the angiotensinogen (AGT) gene, plasma AGT, and hypertension status in a sample of Nigerians. Methods and Results Participants were selected from the extremes of the blood pressure distribution obtained ...
C, Rotimi +6 more
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Background We evaluated the association among the M235T and T174M variants of the angiotensinogen (AGT) gene, plasma AGT, and hypertension status in a sample of Nigerians. Methods and Results Participants were selected from the extremes of the blood pressure distribution obtained ...
C, Rotimi +6 more
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Biochemistry and Regulation of Angiotensinogen
Clinical and Experimental Hypertension. Part A: Theory and Practice, 1983Angiotensin II and angiotensin III, the active peptides of the renin-angiotensin system, are produced by a cascade of enzymatic reactions, whose initial step is the reaction between renin and its substrate, angiotensinogen. In plasma, the concentration of angiotensinogen is a limiting factor: the Km of the enzymatic reaction is between 1 and 2 microM ...
J, Ménard +4 more
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Biochemical and Biophysical Research Communications, 1998
Adipose tissue is an important source of angiotensinogen (AT) after liver. Since an association exists between body mass index, hypertension, and insulin-resistance, the role of insulin on the regulation of AT gene expression and AT secretion was examined in cultured Ob1771 and 3T3-F442A adipose cells.
J, Aubert +3 more
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Adipose tissue is an important source of angiotensinogen (AT) after liver. Since an association exists between body mass index, hypertension, and insulin-resistance, the role of insulin on the regulation of AT gene expression and AT secretion was examined in cultured Ob1771 and 3T3-F442A adipose cells.
J, Aubert +3 more
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Structural Aspects of Rat Angiotensinogen
Clinical and Experimental Hypertension. Part A: Theory and Practice, 1983Rat angiotensinogen (Ao) consists of two molecular weight forms (Ao-1 and Ao-2). The amino acid composition of both forms is very similar. In addition, the immunological properties of both molecules obtained by immunodiffusion and direct radioimmunoassay are very similar as well.
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Journal of Neurochemistry, 1987
Abstract: Angiotensinogen (Aogen) (CA 11002–13–14), the prohormone of the neuro‐ and vasoactive peptide angioten‐ sin II (Ang II) (CA 11128–99–7), is found in dog brain as well as in dog plasma. At 2–4 μg/ml CSF, Aogen comprises 1‐ 2% of the total protein in dog CSF.
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Abstract: Angiotensinogen (Aogen) (CA 11002–13–14), the prohormone of the neuro‐ and vasoactive peptide angioten‐ sin II (Ang II) (CA 11128–99–7), is found in dog brain as well as in dog plasma. At 2–4 μg/ml CSF, Aogen comprises 1‐ 2% of the total protein in dog CSF.
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Silencing Angiotensinogen in Hypertension
New England Journal of Medicine, 2023openaire +2 more sources