Results 31 to 40 of about 18,359 (214)
Turkish Journal of Nephrology, 2019 Objective: Several studies have shown that local renin–angiotensin system (RAS) activity in the kidneys may play a role in the pathogenesis of hypertension and kidney damage in patients with chronic kidney disease.
Tolga YILDIRIM +8 more
doaj +1 more source
Study of Urinary Angiotensinogen as an Indicator of Severity of Diabetic Nephropathy in Type 2 Diabetes [PDF]
Zagazig University Medical JournalBackground: Urinary angiotensinogen levels are higher in type 2 diabetes patients with nephropathy, a risk factor for developing renal and cardiovascular consequences.
Usama Ragab +5 more
doaj +1 more source
An unexpected link between angiotensinogen and thrombin [PDF]
, 2011 Wang Y, Ragg H. An unexpected link between angiotensinogen and thrombin. FEBS Letters. 2011;585(14):2395-2399.Angiotensinogen is well known as source protein for a group of potent vasoactive hormones, however, a discrete biochemical activity of the ...
Hermann Ragg +3 more
core +1 more source
Journal of Veterinary Internal Medicine, 2022 Background The role of the renin‐angiotensin‐aldosterone system in cats with chronic kidney disease (CKD) is incompletely understood. Objective To characterize components of the intrarenal renin‐angiotensin system (RAS) in cats with CKD.
Bianca N. Lourenço +5 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2023 Background and objectiveWhole body manipulation of the renin-angiotensin system (RAS) consistently exerts profound effects on experimental atherosclerosis development. A deficit in the literature has been a lack of attention to the effects of sex.
Masayoshi Kukida +19 more
doaj +1 more source
BRADYKININOGEN, ANGIOTENSINOGEN AND KALLIDINOGEN [PDF]
British Journal of Pharmacology and Chemotherapy, 1963 The plasma globulins which produce the vasoactive polypeptides, bradykinin, kallidin and angiotensin, have been compared. After incubation of plasma with kallikrein and exhaustion of its kallidinogen, subsequent incubation with trypsin did not result in formation of bradykinin, showing that bradykininogen had also been exhausted and suggesting that ...
openaire +2 more sources
Partial purification of dog angiotensinogen.
, 1979 Dog angiotensinogen was purified 450-fold from the plasma of nephrectomized dogs by a simple four-step procedure involving precipitation between 1.5 and 2.3 M ammonium sulfate, gel filtration on Sephadex G-150, ion-exchange chromatography on DE-52 ...
B J Morris, B Moffat, I A Reid
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza +12 more
wiley +1 more source
Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality
BMEMat, EarlyView.Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim +9 more
wiley +1 more source
Cells, 2021 We investigated the expression of components of the renin-angiotensin system (RAS) by cancer stem cell (CSC) subpopulations in metastatic head and neck cutaneous squamous cell carcinoma (mHNcSCC).
Sam Siljee +9 more
doaj +1 more source