Results 11 to 20 of about 28,097 (222)

Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis [PDF]

, 2017
IgA nephropathy (IgAN) is the most prevalent among primary glomerular diseases worldwide. Although our understanding of IgAN has advanced significantly, its underlying biology and potential drug targets are still unexplored.
Cisek, Katryna, Delles, Christian, Filip, Szymon, Gakiopoulou, Chara, Jankowski, Joachim, Krochmal, Magdalena, Markoska, Katerina, Mischak, Harald, Orange, Clare, Spasovski, Goce, Vlahou, Antonia, Zoidakis, Jerome   +11 more
core   +12 more sources

Urinary Angiotensinogen-Melatonin Ratio in Gestational Diabetes and Preeclampsia

Frontiers in Molecular Biosciences, 2022
Background: A large research portfolio indicates that an activated renal renin-angiotensin system or a deficit on melatonin is associated with several cardiovascular pathologies.
Gabriela Ribeiro Valias, Patricia Rodrigues Lourenço Gomes, Fernanda G. Amaral, Saif Alnuaimi, Daniela Monteiro, Siobhán O'Sullivan, Renato Zangaro, José Cipolla-Neto, Juan Acuna, Ovidiu Constantin Baltatu, Ovidiu Constantin Baltatu, Luciana Aparecida Campos, Luciana Aparecida Campos   +12 more
doaj   +1 more source

Effect of Hydrocortisone on Angiotensinogen (AGT) Mutation–Causing Autosomal Recessive Renal Tubular Dysgenesis

Cells, 2021
We has identified a founder homozygous E3_E4 del: 2870 bp deletion + 9 bp insertion in AGT gene encoding angiotensinogen responsible for autosomal recessive renal tubular dysgenesis (ARRTD) with nearly-fatal outcome.
Min-Hua Tseng, Shih-Ming Huang, Martin Konrad, Jing-Long Huang, Steven W. Shaw, Ya-Chung Tian, Ho-Yen Chueh, Wen-Lang Fan, Tai-Wei Wu, Jhao-Jhuang Ding, Ming-Chou Chiang, Shih-Hua Lin   +11 more
doaj   +1 more source

Angiotensinogen and the Modulation of Blood Pressure

Frontiers in Cardiovascular Medicine, 2021
The angiotensin peptides that control blood pressure are released from the non-inhibitory plasma serpin, angiotensinogen, on cleavage of its extended N-terminal tail by the specific aspartyl-protease, renin. Angiotensinogen had previously been assumed to
Zimei Shu, Jiahui Wan, Randy J. Read, Robin W. Carrell, Aiwu Zhou   +4 more
doaj   +1 more source

Urinary excretion of angiotensinogen reflects intrarenal angiotensinogen production [PDF]

Kidney International, 2002
In rats maintained on a high salt diet (H/S) to suppress basal renal angiotensinogen levels, angiotensin II (Ang II) infusion for 13 days increased renal angiotensinogen mRNA and protein, thus providing a mechanism for further augmentation of intrarenal Ang II levels.
Kobori, Hiroyuki, Harrison-Bernard, Lisa M., Navar, L. Gabriel   +2 more
openaire   +2 more sources

Rapid Trio Exome Sequencing for Autosomal Recessive Renal Tubular Dysgenesis in Recurrent Oligohydramnios

Frontiers in Genetics, 2021
Oligohydramnios is not a rare prenatal finding. However, recurrent oligohydramnios is uncommon, and genetic etiology should be taken into consideration.
Shin-Yu Lin, Gwo-Tsann Chuang, Chien-Hui Hung, Wei-Chou Lin, Yung-Ming Jeng, Ting-An Yen, Karine Chang, Yin-Hsiu Chien, Yin-Hsiu Chien, Wuh-Liang Hwu, Wuh-Liang Hwu, Chien-Nan Lee, I-Jung Tsai, Ni-Chung Lee, Ni-Chung Lee   +14 more
doaj   +1 more source

Interleukin-6 mediates angiotensinogen gene expression during liver regeneration.

PLoS ONE, 2013
BackgroundAngiotensinogen is the precursor of angiotensin II, which is associated with ischemia-reperfusion injury. Angiotensin II reduces liver regeneration after hepatectomy and causes dysfunction and failure of reduced-size liver transplants. However,
Hong-Shiee Lai, Wen-Hsi Lin, Shuo-Lun Lai, Hao-Yu Lin, Wen-Ming Hsu, Chia-Hung Chou, Po-Huang Lee   +6 more
doaj   +1 more source

Insulin mediated upregulation of the renin angiotensin system in human subcutaneous adipocytes is reduced by Rosiglitazone [PDF]

, 2005
Background: Obesity associated hypertension is likely to be due to multiple mechanisms. Identification of the renin-angiotensin system (RAS) within adipose tissue does, however, suggest a potential causal role for it in obesity-associated hypertension ...
Chetty, Rajkumar, Coppack, Simon, Harte, A. L. (Alison L.), Katz, Jonathan, Kumar, Sudhesh, McTernan, P. G. (Philip G.), Smith, Stephen   +6 more
core   +1 more source

Urinary excretion of RAS, BMP, and WNT pathway components in diabetic kidney disease. [PDF]

, 2014
The renin-angiotensin system (RAS), bone morphogenetic protein (BMP), and WNT pathways are involved in pathogenesis of diabetic kidney disease (DKD).
Afkarian, Maryam, de Boer, Ian H, Greenbaum, Carla, Himmelfarb, Jonathan, Hirsch, Irl B, Tuttle, Katherine R   +5 more
core   +1 more source

Effects of aqueous saffron extract on glucoregulation as well as hepatic agt and TNF-α gene expression in rats subjected to sub-chronic stress

Advanced Biomedical Research, 2023
Background: Stress and saffron seem to affect glucoregulation mechanisms and insulin resistance in different ways. Impacts of the aqueous saffron extract were investigated on serum glucose levels, serum insulin levels, the homeostatic model assessment of
Yeganeh Yazdani, Maryam Radahmadi, Roshanak Roustazade   +2 more
doaj   +1 more source