Results 11 to 20 of about 18,359 (214)

Angiotensinogen and the Modulation of Blood Pressure [PDF]

Frontiers in Cardiovascular Medicine, 2021
The angiotensin peptides that control blood pressure are released from the non-inhibitory plasma serpin, angiotensinogen, on cleavage of its extended N-terminal tail by the specific aspartyl-protease, renin. Angiotensinogen had previously been assumed to
Zimei Shu, Jiahui Wan, Randy J. Read, Robin W. Carrell, Aiwu Zhou   +4 more
doaj   +11 more sources

Urinary excretion of angiotensinogen reflects intrarenal angiotensinogen production [PDF]

Kidney International, 2002
In rats maintained on a high salt diet (H/S) to suppress basal renal angiotensinogen levels, angiotensin II (Ang II) infusion for 13 days increased renal angiotensinogen mRNA and protein, thus providing a mechanism for further augmentation of intrarenal Ang II levels.
Kobori, Hiroyuki, Harrison-Bernard, Lisa M., Navar, L. Gabriel   +2 more
openaire   +4 more sources

Interleukin-6 mediates angiotensinogen gene expression during liver regeneration.

PLoS ONE, 2013
BackgroundAngiotensinogen is the precursor of angiotensin II, which is associated with ischemia-reperfusion injury. Angiotensin II reduces liver regeneration after hepatectomy and causes dysfunction and failure of reduced-size liver transplants. However,
Hong-Shiee Lai, Wen-Hsi Lin, Shuo-Lun Lai, Hao-Yu Lin, Wen-Ming Hsu, Chia-Hung Chou, Po-Huang Lee   +6 more
doaj   +2 more sources

Clearance of rabbit plasma angiotensinogen and relationship to CSF angiotensinogen

American Journal of Physiology-Heart and Circulatory Physiology, 1983
Rabbit plasma angiotensinogen was purified 1,390-fold by classical purification procedures. Analytical polyacrylamide gel electrophoresis and direct activity assay revealed that the purified preparations were greater than 90% native angiotensinogen.
J A, Lewicki, J M, Printz, M P, Printz
openaire   +3 more sources

Regulation of Angiotensinogen Gene

American Journal of Hypertension, 1989
The development of recombinant DNA technology has introduced new directions for the study of the angiotensinogen molecule. The cloning and sequencing of the human and rat cDNAs demonstrate the similarity of angiotensinogen to various serine protease inhibitors produced by the liver and was the beginning of studies looking for new physiological roles of
Clauser, E., Gaillard, Isabelle, Wei, Lumei, Corvol, P.   +3 more
openaire   +4 more sources

Angiotensinogen – a marker of non-developing pregnancy

Медицинский вестник Юга России
Objective: to investigate the effects of angiotensinogen on the endometrium in missed abortion. Materials and methods: a prospective cohort that included 212 women, 160 with missed abortion and 52 with progressing pregnancies at 6–12 weeks.
A. A. Orazmuradov, Zh. Zh. Suleymanova, E. A. Kuzmina, I. N. Kostin, Kh. Haddad, E. V. Mukovnikova   +5 more
doaj   +2 more sources

Urinary angiotensinogen is a marker for tubular injuries in patients with type 2 diabetes

International Journal of Nephrology and Renovascular Disease, 2013
Takahiro Terami,1 Jun Wada,1 Kentaro Inoue,1 Atsuko Nakatsuka,1,2 Daisuke Ogawa,1,2 Sanae Teshigawara,1 Kazutoshi Murakami,1,3 Akihiro Katayama,1 Jun Eguchi,1 Hirofumi Makino11Department of Medicine and Clinical Science, 2Department of Diabetic ...
Terami T, Wada J, Inoue K, Nakatsuka A, Ogawa D, Teshigawara S, Murakami K, Katayama A, Eguchi J, Makino H   +9 more
doaj   +1 more source

Purification of Rat Angiotensinogen

Preparative Biochemistry, 1986
A method of purifying rat angiotensinogen in three chromatography steps with a yield 3-4 times better than previous methods is described. Using chromatofocusing media for two steps and DEAE-affigel blue for the third step it was possible to separate angiotensinogen into three major peaks with pI of 5.25 (peak B), 4.80 (peak C) and 4.50 (peak D).
Sernia, C, Davis, M, Thomas, WG
openaire   +6 more sources

Mass spectrometry-based urinary proteomic analysis in feline chronic kidney disease. [PDF]

Physiol Rep
Abstract Chronic kidney disease (CKD) is highly prevalent in domestic cats (Felis catus), which might serve as a spontaneous disease model for human CKD. Urinary proteomics is a promising tool for CKD diagnosis and management; yet, minimal information is available in cats. This study aimed to explore the urinary proteome in cats with CKD and assess its
Huang JHC, Lourenço BN, Schmiedt CW, Phillips DR.   +3 more
europepmc   +2 more sources

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source