Results 121 to 130 of about 1,162 (153)

Disruption of the angiopoietin-like system connects lipid homeostasis and hypothalamic dysfunction in ALS. [PDF]

open access: yesBMC Med
Krishnamurthy SS   +19 more
europepmc   +1 more source

ANGPTL8/Betatrophin Does Not Control Pancreatic Beta Cell Expansion [PDF]

open access: yesCell, 2014
Recently, it was reported that angiopoietin-like protein 8 (ANGPTL8) was the long-sought "betatrophin" that could control pancreatic beta cell proliferation. However, studies of Angptl8(?/?) mice revealed profound reduction of triglyceride levels, but no abnormalities in glucose homeostasis.
Andrew J Murphy   +2 more
exaly   +3 more sources

Perspectives on the Activities of ANGPTL8/Betatrophin [PDF]

open access: yesCell, 2014
In this issue of Cell, Gusarova et al. (2014) show that deletion of ANGPTL8 in mice does not affect the compensatory proliferation of pancreatic beta cells in response to insulin resistance induced by a high-fat diet or treatment with the insulin antagonist S961. They also show that overexpression of human ANGPTL8 in mouse liver leads to elevated serum
Peng Yi, Douglas A Melton
exaly   +3 more sources

ANGPTL8 in cardio-metabolic diseases

Clinica Chimica Acta, 2021
Dyslipidemia has been identified as an important factor in obesity, diabetes mellitus, and cardiovascular diseases (CVD), grouped as cardio-metabolic disorder diseases. Accordingly, dyslipidemia has become a major determinant in health worldwide.
Xin, Su, Ye, Cheng, Bin, Wang
openaire   +2 more sources

ANGPTL8 (betatrophin) role in diabetes and metabolic diseases

Diabetes/Metabolism Research and Reviews, 2017
SummaryDiabetes is a major disease worldwide that is reaching epidemic levels. Its increased prevalence as well as its association with a high number of complications such as cardiovascular diseases, nephropathy, and retinopathy makes it an important disease for investigation.
Mohamed Abu-Farha   +2 more
exaly   +3 more sources

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