Emerging Regulation and Function of Betatrophin [PDF]
International Journal of Molecular Sciences, 2014 Betatrophin, also known as TD26/RIFL/lipasin/ANGPTL8/C19orf80, is a novel protein predominantly expressed in human liver. To date, several betatrophin orthologs have been identified in mammals.
Yi-Hsin Tseng, , Wei-Jan Chen
exaly +4 more sources
Irisin and betatrophin responses to 9 h of passive heat exposure: Influence of age, hypertension, and type 2 diabetes [PDF]
Physiological ReportsAge‐ and disease‐related metabolic responses to prolonged passive heat exposure are poorly understood. We evaluated serum irisin and betatrophin responses to 9 h of passive heat exposure (40°C, 9% relative humidity) in 19 young adults (19–31 years) and ...
Joel M. Garrett +7 more
doaj +3 more sources
Increased Circulating Betatrophin Concentrations in Patients with Type 2 Diabetes [PDF]
International Journal of Endocrinology, 2014 Betatrophin has recently been described as a key hormone to stimulate beta-cell mass expansion in response to insulin resistance and obesity in mice. The finding has generated an interest in the development of antidiabetic drugs with betatrophin as the ...
Daniel Espes +2 more
doaj +6 more sources
High betatrophin in coronary patients protects from cardiovascular events
Atherosclerosis, 2020 BACKGROUND AND AIMS Betatrophin, also known as angiopoietin-like protein 8 (ANGPTL8) or lipasin, is a nutritionally-regulated mammalian-specific protein secreted by the liver and adipose tissue.
Andreas Leiherer +2 more
exaly +5 more sources
Gender-Dependent Associations between Serum Betatrophin Levels and Lipoprotein Subfractions in Diabetic and Nondiabetic Obese Patients [PDF]
Int J Mol Sci, 2023 Betatrophin, also known as angiopoietin-like protein 8 (ANGPTL8), mainly plays a role in lipid metabolism. To date, associations between betatrophin and lipoprotein subfractions are poorly investigated.
Lőrincz H +7 more
europepmc +2 more sources
Plasma and aqueous levels of subfatin, preptin and betatrophin in patients with diabetic retinopathy [PDF]
BMC Ophthalmology, 2023 Aim To examine subfatin, preptin and betatrophin levels in plasma and aqueous in patients with diabetes mellitus (DM) (with and without retinopathy). Material and method Sixty patients, who were similar in terms of age and gender, and were scheduled for ...
Sabiha Güngör Kobat +6 more
doaj +2 more sources
Betatrophin association with serum triglyceride levels in obstructive sleep apnea patients
Annals of Thoracic Medicine, 2019 BACKGROUND: Obstructive sleep apnea (OSA) is a common sleep problem, in which patients are at increased risk for metabolic and cardiovascular problems, including metabolic syndrome, diabetes mellitus (DM), and dyslipidemia. Betatrophin is a novel protein
Bunyamin Sertogullarindan +5 more
doaj +2 more sources
Residual beta-cell function in children with type 1 diabetes after a partial remission phase – a possible relation between C-peptide and betatrophin [PDF]
Frontiers in EndocrinologyIntroductionMaintaining endogenous insulin secretion in type 1 diabetes (T1D) long after its onset, and thus the need for early diagnosis and searching for factors preserving the secretory function of β-cells, has become an important goal of current ...
Emilia Odyjewska +4 more
doaj +2 more sources
Betatrophin Acts as a Diagnostic Biomarker in Type 2 Diabetes Mellitus and Is Negatively Associated with HDL-Cholesterol [PDF]
International Journal of Endocrinology, 2015 Objective. By assessing its circulating concentrations in type 2 diabetes mellitus (T2DM) patients, we aimed to explore the associations of betatrophin with various metabolic parameters and evaluate its diagnostic value in T2DM. Methods.
Min Yi +5 more
doaj +2 more sources
ANGPTL8/Betatrophin Improves Glucose Tolerance in Older Mice and Metabolomic Analysis Reveals Its Role in Insulin Resistance in HepG2 Cells [PDF]
Diabetes, Metabolic Syndrome and Obesity, 2021 Fangfang Xu,1 Nan Wang,2 Gangqiang Li,2 Dandan Tian,3 Xiaoyang Shi4 1Clinical Medical Research Center, Department of Research and Discipline Development, Henan Provincial People’s Hospital, Zhengzhou University People’s Hospital, Henan University People ...
Xu F, Wang N, Li G, Tian D, Shi X
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