Results 31 to 40 of about 1,252 (192)

Combinatorial pathway disruption is a powerful approach to delineate metabolic impacts of endocrine disruptors

FEBS Letters, Volume 596, Issue 24, Page 3107-3123, December 2022., 2022
In this review, we describe endocrine disruptor (ED)‐related alterations in tissues involved in metabolic homeostasis, that is, adipose tissue, liver, pancreas, intestine and brain. We also present epigenetic effects of EDs. Finally, we propose an integrative view of multi‐organ alterations that explain how EDs can contribute to the development of ...
Kévin Bernal, Charbel Touma, Chedi Erradhouani, Talía Boronat‐Belda, Lucas Gaillard, Sara Al Kassir, Hélène Le Mentec, Corinne Martin‐Chouly, Normand Podechard, Dominique Lagadic‐Gossmann, Sophie Langouet, François Brion, Anja Knoll‐Gellida, Patrick J. Babin, Iva Sovadinova, Pavel Babica, Karine Andreau, Robert Barouki, Jan Vondracek, Paloma Alonso‐Magdalena, Etienne Blanc, Min Ji Kim, Xavier Coumoul   +22 more
wiley   +1 more source

The effect of long-term strength training on serum levels of betatrophin and irisin in elderly men with type 2 diabetes [PDF]

مجله پزشکی دانشگاه علوم پزشکی تبریز, 2023
Background. The irisin and betatrophin hormones are involved in insulin resistance. Considering the muscle weakness of elderly diabetics, this study aimed to investigate the effect of 21 weeks of strength training on betatrophin and irisin serum levels ...
Mirabdullah Tahramuzi, Farnaz Seifi-Skishahr, Roghayyeh Afroundeh, Leila Katebi, Reza Farzi zadeh   +4 more
doaj   +1 more source

Clinical Value of Circulating Angiopoietin-like Protein 8/Betatrophin Levels in Patients with Acute Pancreatitis. [PDF]

Medicina (Kaunas)
Background and Objectives: Acute pancreatitis (AP) is an inflammatory disorder of the pancreas, with severe cases linked to a higher mortality rate. The prognosis of AP is influenced by factors such as necrosis, secondary infections, and organ failure ...
Gumuskaya PO, Yildirim E, Altun O, Uzun H.   +3 more
europepmc   +3 more sources

Review of potential biomarkers of inflammation and kidney injury in diabetic kidney disease

Diabetes/Metabolism Research and Reviews, Volume 38, Issue 6, September 2022., 2022
Abstract Diabetic kidney disease is expected to increase rapidly over the coming decades with rising prevalence of diabetes worldwide. Current measures of kidney function based on albuminuria and estimated glomerular filtration rate do not accurately stratify and predict individuals at risk of declining kidney function in diabetes.
Vuthi Khanijou, Neda Zafari, Melinda T. Coughlan, Richard J. MacIsaac, Elif I. Ekinci   +4 more
wiley   +1 more source

MicroRNAs as the promising markers of comorbidities in childhood obesity—A systematic review

Pediatric Obesity, Volume 17, Issue 6, June 2022., 2022
Summary Introduction Rising child obesity rate creates a need for tools quantifying changes in children suffering from obesity, for purposes of detection or prevention of comorbidities. A candidate for such a role seems to be microRNAs, which in vivo serve as the suppressing factors in gene expression.
Michał Hutny, Jagoda Hofman, Agnieszka Zachurzok, Paweł Matusik   +3 more
wiley   +1 more source

Serum betatrophin level of newly diagnosed and chronic diabetic patients and its relationship with metabolic parameters

Chronic Diseases Journal, 2022
BACKGROUND: Angiopoietin-like protein 8 (ANGPTL8) that was originally called betatrophin is a novel growth factor which is mainly secreted by the liver and associated with diabetes.
Leila Pirmoradi, Ebrahim Ghaderi
doaj   +1 more source

NF‐κB signalling pathways in nucleus pulposus cell function and intervertebral disc degeneration

Cell Proliferation, Volume 54, Issue 7, July 2021., 2021
Intervertebral disc degeneration (IDD) is a common clinical degenerative disease of the spine. A series of factors, such as inflammation, oxidative stress, and mechanical stress, promote degradation of the extracellular matrix (ECM) of the intervertebral discs (IVD), leading to dysfunction and structural destruction of the IVD. Nuclear factor‐κB (NF‐κB)
Guang‐Zhi Zhang, Ming‐Qiang Liu, Hai‐Wei Chen, Zuo‐Long Wu, Yi‐Cheng Gao, Zhan‐Jun Ma, Xue‐Gang He, Xue‐Wen Kang   +7 more
wiley   +1 more source

Betatrophin [PDF]

Islets, 2014
Regenerative therapy in diabetes with the capacity to reconstitute a functional β-cell mass sufficient for glycemic control holds the promise to effectively prevent the development of devastating late complications due to the unique ability of the β-cell to sense and regulate blood-glucose levels.
Ahnfelt-Rønne, Jonas, Madsen, Ole D
openaire   +1 more source

High Serum Asprosin Levels Are Associated with Presence of Metabolic Syndrome

International Journal of Endocrinology, Volume 2021, Issue 1, 2021., 2021
Objective. Asprosin, a new adipocytokine, has reportedly been associated with glucose release, dyslipidemia, and insulin resistance (IR). However, the relationship of asprosin with metabolic syndrome (MetS) remains unknown. This study aimed to investigate serum asprosin levels in MetS as well as their association with various metabolic parameters in ...
Tao Hong, Jiao-Yang Li, Ya-Di Wang, Xiao-Yan Qi, Zhe-Zhen Liao, Poonam Bhadel, Li Ran, Jing Yang, Bin Yan, Jiang-Hua Liu, Xin-Hua Xiao, Arturo Bevilacqua   +11 more
wiley   +1 more source

Correlation of serum betatrophin levels with disease severity and the emergence of insulin resistance in cirrhotic patients

Egyptian Liver Journal, 2020
Background Insulin resistance (IR) is frequently associated with chronic liver disease. There has been an increased interest in betatrophin protein and its involvement in the compensatory response to IR.
Mohamed Magdy Salama, Walaa Ahmed Kabiel, Silvia Shoukry Hana, Ghada Abdelrahman Mohamed   +3 more
doaj   +1 more source