Association of metabolic syndrome components with circulating levels of cytokine clusters in young women [PDF]
Endocrine Connections, 2021 Background: The purpose of this study was to investigate the relationship between circulating zinc α 2-glycoprotein (ZAG), irisin, betatrophin and adiponectin concentrations and metabolic syndrome (MetS) components and to analyze the effe cts of blood ...
Xingrong Tan +8 more
doaj +2 more sources
Association between circulating microRNAs 486, 146b and 15b and serum betatrophin levels in obese; type 2 diabetic and non-diabetic children [PDF]
BMC Endocrine Disorders, 2020 Background This study tested the association between serum levels of microRNA-486, −146b and -15b and betatrophin in normal and obese children with/without type 2 diabetes mellitus (T2DM).
Khalid M. Mohany +4 more
doaj +2 more sources
Evaluation of serum levels of sestrin 2 and betatrophin in type 2 diabetic patients with diabetic nephropathy [PDF]
BMC NephrologyBackground Diabetic kidney disease (DKD) is one of the most serious microvascular complications of diabetes mellitus (DM) and the leading cause of chronic kidney disease (CKD) worldwide.
Asmaa Mounir Emara +3 more
doaj +2 more sources
Clinical Value of Circulating Angiopoietin-like Protein 8/Betatrophin Levels in Patients with Acute Pancreatitis [PDF]
MedicinaBackground and Objectives: Acute pancreatitis (AP) is an inflammatory disorder of the pancreas, with severe cases linked to a higher mortality rate. The prognosis of AP is influenced by factors such as necrosis, secondary infections, and organ failure ...
Perihan Ozkan Gumuskaya +3 more
doaj +2 more sources
Increased Cord Blood Betatrophin Levels in the Offspring of Mothers with Gestational Diabetes.
PLoS ONE, 2016 AimExposing a fetus to hyperglycemia can increase the risk for later-life metabolic disorders. Betatrophin has been proposed as a key regulator of pancreatic beta cell proliferation and lipid regulation.
Xuemei Xie +8 more
doaj +2 more sources
Relationship of Serum Betatrophin with Nonalcoholic Fatty Liver in a Chinese Population.
PLoS ONE, 2017 ObjectiveThis study aimed to investigate the association of serum betatrophin with the status and progression of nonalcoholic fatty liver disease (NAFLD).MethodsA total of 249 subjects who received ultrasonic examination of liver fat content (LFC) were ...
Wen Hu +9 more
doaj +3 more sources
Anti proliferative and apoptotic effects on pancreatic cancer cell lines indicate new roles for ANGPTL8 (Betatrophin) [PDF]
Genetics and Molecular Biology, 2020 Despite considerable advances, the treatment of pancreatic cancer (PC) still requires much effort. Unusual regulation of the Wnt and apoptotic signaling pathways is widespread in cancer incidence.
Fatemeh Taherkhani +4 more
doaj +2 more sources
Circulating Betatrophin Is Strongly Increased in Pregnancy and Gestational Diabetes Mellitus. [PDF]
PLoS ONE, 2015 Betatrophin has recently been introduced as a novel hormone and promotor of beta cell proliferation and improved glucose tolerance in mouse models of insulin resistance.
Lana Kosi Trebotic +7 more
doaj +4 more sources
PLoS ONE, 2017 ObjectiveThe association between circulating betatrophin levels and gestational diabetes mellitus (GDM) is controversial. The aim of our study was to systematically review available literature linking betatrophin to GDM for a comprehensive understanding ...
Fei-Juan Kong +4 more
doaj +2 more sources
Circulating Betatrophin in Patients with Type 2 Diabetes: A Meta-Analysis
Journal of Diabetes Research, 2016 Objective. To investigate the association between circulating betatrophin level and type 2 diabetes mellitus (T2DM) in human. Methods. A comprehensive literature search was performed in PubMed and Embase databases to identify eligible studies assessing ...
Sheyu Li +7 more
doaj +2 more sources