Results 31 to 40 of about 546 (155)

Plasma Betatrophin Levels and Carotid Atherosclerosis [PDF]

Disease Markers, 2019
Aims. Betatrophin is a recently identified circulating adipokine that may affect lipid and glucose metabolism. However, the association between plasma betatrophin levels and carotid atherosclerosis has not been elucidated. Methods. We investigated plasma betatrophin levels in 153 subjects undergoing carotid ultrasonography.
Hanako Niki, Yoshimi Kishimoto, Emi Saita, Reiko Ohmori, Kazuo Kondo, Yukihiko Momiyama   +5 more
openaire   +2 more sources

MicroRNAs as the promising markers of comorbidities in childhood obesity—A systematic review

Pediatric Obesity, Volume 17, Issue 6, June 2022., 2022
Summary Introduction Rising child obesity rate creates a need for tools quantifying changes in children suffering from obesity, for purposes of detection or prevention of comorbidities. A candidate for such a role seems to be microRNAs, which in vivo serve as the suppressing factors in gene expression.
Michał Hutny, Jagoda Hofman, Agnieszka Zachurzok, Paweł Matusik   +3 more
wiley   +1 more source

The effect of long-term strength training on serum levels of betatrophin and irisin in elderly men with type 2 diabetes [PDF]

مجله پزشکی دانشگاه علوم پزشکی تبریز, 2023
Background. The irisin and betatrophin hormones are involved in insulin resistance. Considering the muscle weakness of elderly diabetics, this study aimed to investigate the effect of 21 weeks of strength training on betatrophin and irisin serum levels ...
Mirabdullah Tahramuzi, Farnaz Seifi-Skishahr, Roghayyeh Afroundeh, Leila Katebi, Reza Farzi zadeh   +4 more
doaj   +1 more source

NF‐κB signalling pathways in nucleus pulposus cell function and intervertebral disc degeneration

Cell Proliferation, Volume 54, Issue 7, July 2021., 2021
Intervertebral disc degeneration (IDD) is a common clinical degenerative disease of the spine. A series of factors, such as inflammation, oxidative stress, and mechanical stress, promote degradation of the extracellular matrix (ECM) of the intervertebral discs (IVD), leading to dysfunction and structural destruction of the IVD. Nuclear factor‐κB (NF‐κB)
Guang‐Zhi Zhang, Ming‐Qiang Liu, Hai‐Wei Chen, Zuo‐Long Wu, Yi‐Cheng Gao, Zhan‐Jun Ma, Xue‐Gang He, Xue‐Wen Kang   +7 more
wiley   +1 more source

Serum betatrophin and irisin levels in hepatocellular carcinoma. [PDF]

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2020
Hepatocellular carcinoma (HCC) development is a complex process with well-known risk factors, however the role of betatrophin/angiopoietin-like protein 8 and irisin has been poorly investigated thus far. The aim of this study is to measure betatrophin and irisin serum levels in HCC, cirrhotic patients and controls, assess their relationship with cancer
Pazgan-Simon, Monika, Zuwała-Jagiełło, Jolanta, Menżyk, Tomasz, Bator, Martyna, Derra, Aleksandra, Andrzej Lekstan, Grzebyk, Ewa, Simon, Krzysztof, Michał Kukla   +8 more
openaire   +4 more sources

Correlation of serum betatrophin levels with disease severity and the emergence of insulin resistance in cirrhotic patients

Egyptian Liver Journal, 2020
Background Insulin resistance (IR) is frequently associated with chronic liver disease. There has been an increased interest in betatrophin protein and its involvement in the compensatory response to IR.
Mohamed Magdy Salama, Walaa Ahmed Kabiel, Silvia Shoukry Hana, Ghada Abdelrahman Mohamed   +3 more
doaj   +1 more source

Serum betatrophin level of newly diagnosed and chronic diabetic patients and its relationship with metabolic parameters

Chronic Diseases Journal, 2022
BACKGROUND: Angiopoietin-like protein 8 (ANGPTL8) that was originally called betatrophin is a novel growth factor which is mainly secreted by the liver and associated with diabetes.
Leila Pirmoradi, Ebrahim Ghaderi
doaj   +1 more source

High Serum Asprosin Levels Are Associated with Presence of Metabolic Syndrome

International Journal of Endocrinology, Volume 2021, Issue 1, 2021., 2021
Objective. Asprosin, a new adipocytokine, has reportedly been associated with glucose release, dyslipidemia, and insulin resistance (IR). However, the relationship of asprosin with metabolic syndrome (MetS) remains unknown. This study aimed to investigate serum asprosin levels in MetS as well as their association with various metabolic parameters in ...
Tao Hong, Jiao-Yang Li, Ya-Di Wang, Xiao-Yan Qi, Zhe-Zhen Liao, Poonam Bhadel, Li Ran, Jing Yang, Bin Yan, Jiang-Hua Liu, Xin-Hua Xiao, Arturo Bevilacqua   +11 more
wiley   +1 more source

Mesenchymal Stem Cells: An Excellent Candidate for the Treatment of Diabetes Mellitus

International Journal of Endocrinology, Volume 2021, Issue 1, 2021., 2021
Mesenchymal stem cells (MSCs) are adult stem cells (ASCs) known for repairing damaged cells, exerting anti‐inflammatory responses and producing immunoregulatory effects that can be significantly induced into insulin‐producing cells (IPCs), providing an inexhaustible supply of functional β cells for cell replacement therapy and disease modeling for ...
Qiulan Huang, Yanting Huang, Jianping Liu, Andrea Tura   +3 more
wiley   +1 more source

Betting on betatrophin [PDF]

Science-Business eXchange, 2013
Researchers at Harvard have discovered a hormone that promotes pancreatic islet β cell proliferation in mice. Partner companies Evotec and Johnson & Johnson have rights to the molecule and plan to turn it into a preclinical type 2 diabetes candidate this year.
openaire   +1 more source