ANGPTL8/Betatrophin Improves Glucose Tolerance in Older Mice and Metabolomic Analysis Reveals Its Role in Insulin Resistance in HepG2 Cells [PDF]
Diabetes, Metabolic Syndrome and Obesity, 2021 Fangfang Xu,1 Nan Wang,2 Gangqiang Li,2 Dandan Tian,3 Xiaoyang Shi4 1Clinical Medical Research Center, Department of Research and Discipline Development, Henan Provincial People’s Hospital, Zhengzhou University People’s Hospital, Henan University People ...
Xu F, Wang N, Li G, Tian D, Shi X
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Circulating fibroblast growth factor-21, Omentin-1, and betatrophin and their association with metabolic parameters in Saudi adolescents post 12-month lifestyle change program [PDF]
BMC PediatricsBackground Fibroblast growth factor-21 (FGF21) and omentin-1 have been recognized as potent antidiabetic agents with potential hepatoprotective activity.
Mona M. Alenazi +5 more
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Can Betatrophin Predict the Risk of Preeclampsia? [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: Preeclampsia, a hypertensive disease of pregnancy, is globally one of the primary causes of maternal morbidity and mortality. Betatrophin is shown to be a novel adipokine in pathophysiology of metabolic disorders. It plays a role in glucose
Engin Ersin Simsek +3 more
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Association of metabolic syndrome components with circulating levels of cytokine clusters in young women [PDF]
Endocrine Connections, 2021 Background: The purpose of this study was to investigate the relationship between circulating zinc α 2-glycoprotein (ZAG), irisin, betatrophin and adiponectin concentrations and metabolic syndrome (MetS) components and to analyze the effe cts of blood ...
Xingrong Tan +8 more
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Betatrophin Acts as a Diagnostic Biomarker in Type 2 Diabetes Mellitus and Is Negatively Associated with HDL-Cholesterol [PDF]
International Journal of Endocrinology, 2015 Objective. By assessing its circulating concentrations in type 2 diabetes mellitus (T2DM) patients, we aimed to explore the associations of betatrophin with various metabolic parameters and evaluate its diagnostic value in T2DM. Methods.
Min Yi +5 more
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Journal of Endocrinological Investigation, 2018 Betatrophin and fibroblast growth factor-21 (FGF-21), as recently discovered members of hepatokine/adipokine family, have been proposed to be associated with some metabolic disorders in which insulin resistance plays a major role. We aimed to investigate
Alev Eroglu Altinova +2 more
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Association between circulating microRNAs 486, 146b and 15b and serum betatrophin levels in obese; type 2 diabetic and non-diabetic children [PDF]
BMC Endocrine Disorders, 2020 Background This study tested the association between serum levels of microRNA-486, −146b and -15b and betatrophin in normal and obese children with/without type 2 diabetes mellitus (T2DM).
Khalid M. Mohany +4 more
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Increased Cord Blood Betatrophin Levels in the Offspring of Mothers with Gestational Diabetes.
PLoS ONE, 2016 AimExposing a fetus to hyperglycemia can increase the risk for later-life metabolic disorders. Betatrophin has been proposed as a key regulator of pancreatic beta cell proliferation and lipid regulation.
Xuemei Xie +8 more
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Evaluation of serum levels of sestrin 2 and betatrophin in type 2 diabetic patients with diabetic nephropathy [PDF]
BMC NephrologyBackground Diabetic kidney disease (DKD) is one of the most serious microvascular complications of diabetes mellitus (DM) and the leading cause of chronic kidney disease (CKD) worldwide.
Asmaa Mounir Emara +3 more
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Relationship of Serum Betatrophin with Nonalcoholic Fatty Liver in a Chinese Population.
PLoS ONE, 2017 ObjectiveThis study aimed to investigate the association of serum betatrophin with the status and progression of nonalcoholic fatty liver disease (NAFLD).MethodsA total of 249 subjects who received ultrasonic examination of liver fat content (LFC) were ...
Wen Hu +9 more
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