Circulating Betatrophin Is Strongly Increased in Pregnancy and Gestational Diabetes Mellitus. [PDF]
PLoS ONE, 2015 Betatrophin has recently been introduced as a novel hormone and promotor of beta cell proliferation and improved glucose tolerance in mouse models of insulin resistance.
Lana Kosi Trebotic +7 more
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Increased Cord Blood Betatrophin Levels in the Offspring of Mothers with Gestational Diabetes. [PDF]
PLoS ONE, 2016 AimExposing a fetus to hyperglycemia can increase the risk for later-life metabolic disorders. Betatrophin has been proposed as a key regulator of pancreatic beta cell proliferation and lipid regulation.
Xuemei Xie +8 more
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Anti proliferative and apoptotic effects on pancreatic cancer cell lines indicate new roles for ANGPTL8 (Betatrophin) [PDF]
Genetics and Molecular Biology, 2020 Despite considerable advances, the treatment of pancreatic cancer (PC) still requires much effort. Unusual regulation of the Wnt and apoptotic signaling pathways is widespread in cancer incidence.
Fatemeh Taherkhani +4 more
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Circulating fibroblast growth factor-21, Omentin-1, and betatrophin and their association with metabolic parameters in Saudi adolescents post 12-month lifestyle change program [PDF]
BMC PediatricsBackground Fibroblast growth factor-21 (FGF21) and omentin-1 have been recognized as potent antidiabetic agents with potential hepatoprotective activity.
Mona M. Alenazi +5 more
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ANGPTL8/Betatrophin Improves Glucose Tolerance in Older Mice and Metabolomic Analysis Reveals Its Role in Insulin Resistance in HepG2 Cells [PDF]
Diabetes, Metabolic Syndrome and Obesity, 2021 Fangfang Xu,1 Nan Wang,2 Gangqiang Li,2 Dandan Tian,3 Xiaoyang Shi4 1Clinical Medical Research Center, Department of Research and Discipline Development, Henan Provincial People’s Hospital, Zhengzhou University People’s Hospital, Henan University People ...
Xu F, Wang N, Li G, Tian D, Shi X
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Association of metabolic syndrome components with circulating levels of cytokine clusters in young women [PDF]
Endocrine Connections, 2021 Background: The purpose of this study was to investigate the relationship between circulating zinc α 2-glycoprotein (ZAG), irisin, betatrophin and adiponectin concentrations and metabolic syndrome (MetS) components and to analyze the effe cts of blood ...
Xingrong Tan +8 more
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PLoS ONE, 2017 ObjectiveThe association between circulating betatrophin levels and gestational diabetes mellitus (GDM) is controversial. The aim of our study was to systematically review available literature linking betatrophin to GDM for a comprehensive understanding ...
Fei-Juan Kong +4 more
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Evaluation of serum levels of sestrin 2 and betatrophin in type 2 diabetic patients with diabetic nephropathy [PDF]
BMC NephrologyBackground Diabetic kidney disease (DKD) is one of the most serious microvascular complications of diabetes mellitus (DM) and the leading cause of chronic kidney disease (CKD) worldwide.
Asmaa Mounir Emara +3 more
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Data on the power of high betatrophin to predict cardiovascular deaths in coronary patients. [PDF]
, 2020 Betatrophin is a protein which is produced by the liver and by adipose tissue. There are no clear data about serum betatrophin's cardiovascular role and it is unknown, whether betatrophin is associated with the risk of cardiovascular death.
Geiger, Kathrin +7 more
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An Analysis of Circulating Betatrophin Levels in Relation with Type1 and Type2 Diabetes Mellitu Running Title: Betatrophin and Diabetes [PDF]
Annals of Endocrinology and Metabolism, 2021 Betatrophin is a newly identified liver-derived hormone that is associated with glucose homeostasis and lipid metabolism. Previous researches of betatrophin on glucose and lipid metabolism were mainly done under insulin resistant conditions. Only three studies from two centers investigated the association between betatrophin and type1 diabetes mellitus
Altunoglu Esma +4 more
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