Results 51 to 60 of about 1,252 (192)

Evaluation of the Circulating Betatrophin Concentration and its Possible Correlations Among Diabetic Patients with Dyslipidemia

Endocrinology Research and Practice, 2019
Objective: The circulating betatrophin levels in diabetic patients, treated with insulin or with oral hypoglycemic agents, were measured. The correlation between betatrophin levels and the glucose/lipid variables was also analyzed. Material and Methods:
Rasha M. HUSSEIN
doaj   +1 more source

Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway [PDF]

, 2017
The angiopoietin-like 4 (ANGPTL4) protein belongs to a superfamily of secreted proteins structurally related to factors modulating angiogenesis known as angiopoietins.
Amodeo, V., Bazan, V., Caruso, S., Fanale, D., LA PAGLIA, L., List\ue3\uac, A., Passiglia, F.   +6 more
core   +6 more sources

Betatrophin association with serum triglyceride levels in obstructive sleep apnea patients

Annals of Thoracic Medicine, 2019
BACKGROUND: Obstructive sleep apnea (OSA) is a common sleep problem, in which patients are at increased risk for metabolic and cardiovascular problems, including metabolic syndrome, diabetes mellitus (DM), and dyslipidemia. Betatrophin is a novel protein
Bunyamin Sertogullarindan, Ahmet Ufuk Komuroglu, Rifki Ucler, Hulya Gunbatar, Aysel Sunnetcioglu, Erdem Cokluk   +5 more
doaj   +1 more source

Palmitate induces mRNA translation and increases ER protein load in islet β-cells via activation of the mammalian target of rapamycin pathway [PDF]

, 2014
Saturated free fatty acids (FFAs) have complex effects on the islet β-cell, acutely promoting adaptive hyperplasia but chronically impairing insulin release. The acute effects of FFAs remain incompletely defined. To elucidate these early molecular events,
Evans-Molina, Carmella, Hatanaka, Masayuki, Kulkarni, Rohit N., Maier, Bernhard, Mirmira, Raghavendra G., Sims, Emily K., Templin, Andrew T.   +6 more
core   +1 more source

Circulating Betatrophin Correlates with Triglycerides and Postprandial Glucose among Different Glucose Tolerance Statuses--A Case-Control Study.

PLoS ONE, 2015
PurposePrevious researches of betatrophin on glucose and lipids metabolism under insulin-resistant condition have reached controversial conclusions. To further identify the possible impact of betatrophin, we measured the circulating betatrophin levels in
Ting Gao, Kairui Jin, Peihong Chen, Hua Jin, Lili Yang, Xinmiao Xie, Meili Yang, Cheng Hu, Xuemei Yu   +8 more
doaj   +1 more source

Decrease in fasting insulin secretory function correlates with significant liver fibrosis in Japanese non‐alcoholic fatty liver disease patients

JGH Open, Volume 4, Issue 5, Page 929-936, October 2020., 2020
Japanese patients with NAFLD have significant fibrosis with reduced insulin secretion. These patients also tended to be significantly non‐obese. Abstract Background and Aim Non‐alcoholic fatty liver disease (NAFLD) is typically associated with metabolic syndrome and diabetes, and insulin resistance is involved in its pathogenesis.
Norimasa Araki, Hirokazu Takahashi, Ayako Takamori, Yoichiro Kitajima, Hideyuki Hyogo, Yoshio Sumida, Saiyu Tanaka, Keizo Anzai, Shinichi Aishima, Kazuaki Chayama, Kazuma Fujimoto, Yuichiro Eguchi   +11 more
wiley   +1 more source

Interplay of atherogenic factors, protein intake and betatrophin levels in obese–metabolic syndrome patients treated with hypocaloric diets [PDF]

, 2015
The present research evaluated circulating betatrophin levels in obese patients with metabolic syndrome features under energy-restricted weight-loss programs and in normal weight in order to stablish the putative interplay between the levels of this ...
A Alkerwi, A Astrup, A B Crujeiras, A Fenzl, AB Crujeiras, AB Crujeiras, AB Crujeiras, BK Pedersen, D Espes, DR Matthews, F F Casanueva, F Quagliarini, G Ren, GA Bray, H Hu, I Abete, J A Martínez, J Gomez-Ambrosi, JL Gutierrez-Fisac, JM Friedman, JP Chaput, K Guo, K Wynne, KG Alberti, M A Zulet, M Abu-Farha, M Amil, M C Carreira, M Kojima, MA Martinez-Gonzalez, MS Westerterp-Plantenga, O Al-Massadi, O Gogebakan, P Lopez-Legarrea, P Lopez-Legarrea, P Yi, R de la Iglesia, R Zhang, RH Eckel, Shimin Wu, T Tang, TM Larsen, WT Friedewald, X Chen, Y Li, Y Lin, Y Wang, Z Fu, Z Fu, Z Fu   +49 more
core   +3 more sources

Development of a conditionally immortalized human pancreatic β cell line [PDF]

, 2014
International audienceDiabetic patients exhibit a reduction in β cells, which secrete insulin to help regulate glucose homeostasis; however, little is known about the factors that regulate proliferation of these cells in human pancreas. Access to primary
Bricout-Neveu, Emilie, Czernichow, Paul, Grenier-Godard, Maud, Guez, Fanny, Hazhouz, Yasmine, Lohmann, Matthias, Pechberty, Severine, Rachdi, Latif, Ravassard, Philippe, Scharfmann, Raphaël, Von Bülow, Manon   +10 more
core   +4 more sources

Betatrophin—Promises Fading and Lessons Learned [PDF]

Cell Metabolism, 2014
The discovery of a potent mitogen for insulin-producing pancreatic β cells, optimistically termed "betatrophin," excited researchers and laypeople alike, promising a new therapeutic approach to diabetes. A recent "Matters Arising" report by Gusarova and colleagues (2014) places serious doubts on whether "betatrophin" plays any major role in β cell ...
openaire   +2 more sources

Variation in Circulating Betatrophin/ ANGPTL8 Levels in Normal and Overweight/Obese Pregnant Women [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Betatrophin as hepatokine and adipokine influences glucose homeostasis and implicates in the pathophysiological process of obesity and pregnancy.
Mohammad Ahmad Hamza, Yassar Yahya AL Tamer, Omar Abdul Majeed AL-Habib   +2 more
doaj   +1 more source