Results 41 to 50 of about 1,252 (192)
Mesenchymal Stem Cells: An Excellent Candidate for the Treatment of Diabetes Mellitus
International Journal of Endocrinology, Volume 2021, Issue 1, 2021., 2021 Mesenchymal stem cells (MSCs) are adult stem cells (ASCs) known for repairing damaged cells, exerting anti‐inflammatory responses and producing immunoregulatory effects that can be significantly induced into insulin‐producing cells (IPCs), providing an inexhaustible supply of functional β cells for cell replacement therapy and disease modeling for ...
Qiulan Huang +3 more
wiley +1 more source
Serum betatrophin and irisin levels in hepatocellular carcinoma. [PDF]
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2020 Hepatocellular carcinoma (HCC) development is a complex process with well-known risk factors, however the role of betatrophin/angiopoietin-like protein 8 and irisin has been poorly investigated thus far. The aim of this study is to measure betatrophin and irisin serum levels in HCC, cirrhotic patients and controls, assess their relationship with cancer
Pazgan-Simon, M. +8 more
openaire +4 more sources
An Analysis of Circulating Betatrophin Levels in Relation with Type1 and Type2 Diabetes Mellitu Running Title: Betatrophin and Diabetes [PDF]
Annals of Endocrinology and Metabolism, 2021 Betatrophin is a newly identified liver-derived hormone that is associated with glucose homeostasis and lipid metabolism. Previous researches of betatrophin on glucose and lipid metabolism were mainly done under insulin resistant conditions. Only three studies from two centers investigated the association between betatrophin and type1 diabetes mellitus
Altunoglu Esma +4 more
openaire +1 more source
Metabolic improvements following Roux-en-Y surgery assessed by solid meal test in subjects with short duration type 2 diabetes [PDF]
, 2017 BACKGROUND: Glucose homeostasis improves within days following Roux-en-Y gastric bypass (RYGB) surgery. The dynamic metabolic response to caloric intake following RYGB has been assessed using liquid mixed meal tolerance tests (MMTT).
Acton, Anthony J. +12 more
core +2 more sources
Islets, 2015 Regenerative therapy in diabetes with the capacity to reconstitute a functional β-cell mass sufficient for glycemic control holds the promise to effectively prevent the development of devastating late complications due to the unique ability of the β-cell to sense and regulate blood-glucose levels.
Jonas, Ahnfelt-Rønne, Ole D, Madsen
openaire +2 more sources
Perspectives on the Activities of ANGPTL8/Betatrophin [PDF]
Cell, 2014 In this issue of Cell, Gusarova et al. (2014) show that deletion of ANGPTL8 in mice does not affect the compensatory proliferation of pancreatic beta cells in response to insulin resistance induced by a high-fat diet or treatment with the insulin antagonist S961. They also show that overexpression of human ANGPTL8 in mouse liver leads to elevated serum
Yi, Peng +2 more
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, 2009 Ventura Rodríguez, Ferran (escultor)Pla general d'una part del Fossar. Era Era una antiga pedrera que va es va destinar a enterrar víctimes dels bombardeigs de la guerra civil, de les execucions de la guerra i l'època franquista.
Departament d'Arquitectura i Projectes Urbans +1 more
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(Re)generating human beta cells : status, pitfalls, and perspectives [PDF]
, 2018 Diabetes mellitus results from disturbed glucose homeostasis due to an absolute (type 1) or relative (type 2) deficiency of insulin, a peptide hormone almost exclusively produced by the beta cells of the endocrine pancreas in a tightly regulated manner ...
Baeyens, Luc +7 more
core +2 more sources
Betatrophin Levels were Increased in Pregnant Women with or without Gestational Diabetes Mellitus and Associated with Beta Cell Function [PDF]
Revista Brasileira de Ginecologia e Obstetrícia, 2016 Purpose betatrophin has been reported to boost β cell expansion in insulin resistant states. Pregnancy is a well-recognized physiological state of insulin resistance.
Yun Huang +5 more
doaj +1 more source
Science-Business eXchange, 2013 Researchers at Harvard have discovered a hormone that promotes pancreatic islet β cell proliferation in mice. Partner companies Evotec and Johnson & Johnson have rights to the molecule and plan to turn it into a preclinical type 2 diabetes candidate this year.
openaire +1 more source