Results 41 to 50 of about 814 (180)
Perspectives on the Activities of ANGPTL8/Betatrophin [PDF]
Cell, 2014 In this issue of Cell, Gusarova et al. (2014) show that deletion of ANGPTL8 in mice does not affect the compensatory proliferation of pancreatic beta cells in response to insulin resistance induced by a high-fat diet or treatment with the insulin antagonist S961. They also show that overexpression of human ANGPTL8 in mouse liver leads to elevated serum
Yi, Peng +2 more
openaire +2 more sources
Diabetes/Metabolism Research and Reviews, Volume 39, Issue 4, May 2023., 2023 Abstract Aims This systematic review and meta‐analysis examined maternal and cord blood betatrophin levels in pregnant women with gestational diabetes mellitus (GDM) and normoglycemic controls. Material and Methods PubMed, Cochrane Library, Embase, LILACS, WangFang, and China National Knowledge Infrastructure were searched for literature from inception
Faustino R. Pérez‐López +5 more
wiley +1 more source
FEBS Letters, Volume 596, Issue 24, Page 3107-3123, December 2022., 2022 In this review, we describe endocrine disruptor (ED)‐related alterations in tissues involved in metabolic homeostasis, that is, adipose tissue, liver, pancreas, intestine and brain. We also present epigenetic effects of EDs. Finally, we propose an integrative view of multi‐organ alterations that explain how EDs can contribute to the development of ...
Kévin Bernal +22 more
wiley +1 more source
Review of potential biomarkers of inflammation and kidney injury in diabetic kidney disease
Diabetes/Metabolism Research and Reviews, Volume 38, Issue 6, September 2022., 2022 Abstract Diabetic kidney disease is expected to increase rapidly over the coming decades with rising prevalence of diabetes worldwide. Current measures of kidney function based on albuminuria and estimated glomerular filtration rate do not accurately stratify and predict individuals at risk of declining kidney function in diabetes.
Vuthi Khanijou +4 more
wiley +1 more source
Plasma Betatrophin Levels and Carotid Atherosclerosis [PDF]
Disease Markers, 2019 Aims. Betatrophin is a recently identified circulating adipokine that may affect lipid and glucose metabolism. However, the association between plasma betatrophin levels and carotid atherosclerosis has not been elucidated. Methods. We investigated plasma betatrophin levels in 153 subjects undergoing carotid ultrasonography.
Hanako Niki +5 more
openaire +2 more sources
MicroRNAs as the promising markers of comorbidities in childhood obesity—A systematic review
Pediatric Obesity, Volume 17, Issue 6, June 2022., 2022 Summary Introduction Rising child obesity rate creates a need for tools quantifying changes in children suffering from obesity, for purposes of detection or prevention of comorbidities. A candidate for such a role seems to be microRNAs, which in vivo serve as the suppressing factors in gene expression.
Michał Hutny +3 more
wiley +1 more source
NF‐κB signalling pathways in nucleus pulposus cell function and intervertebral disc degeneration
Cell Proliferation, Volume 54, Issue 7, July 2021., 2021 Intervertebral disc degeneration (IDD) is a common clinical degenerative disease of the spine. A series of factors, such as inflammation, oxidative stress, and mechanical stress, promote degradation of the extracellular matrix (ECM) of the intervertebral discs (IVD), leading to dysfunction and structural destruction of the IVD. Nuclear factor‐κB (NF‐κB)
Guang‐Zhi Zhang +7 more
wiley +1 more source
High Serum Asprosin Levels Are Associated with Presence of Metabolic Syndrome
International Journal of Endocrinology, Volume 2021, Issue 1, 2021., 2021 Objective. Asprosin, a new adipocytokine, has reportedly been associated with glucose release, dyslipidemia, and insulin resistance (IR). However, the relationship of asprosin with metabolic syndrome (MetS) remains unknown. This study aimed to investigate serum asprosin levels in MetS as well as their association with various metabolic parameters in ...
Tao Hong +11 more
wiley +1 more source
Mesenchymal Stem Cells: An Excellent Candidate for the Treatment of Diabetes Mellitus
International Journal of Endocrinology, Volume 2021, Issue 1, 2021., 2021 Mesenchymal stem cells (MSCs) are adult stem cells (ASCs) known for repairing damaged cells, exerting anti‐inflammatory responses and producing immunoregulatory effects that can be significantly induced into insulin‐producing cells (IPCs), providing an inexhaustible supply of functional β cells for cell replacement therapy and disease modeling for ...
Qiulan Huang +3 more
wiley +1 more source
Serum betatrophin and irisin levels in hepatocellular carcinoma. [PDF]
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2020 Hepatocellular carcinoma (HCC) development is a complex process with well-known risk factors, however the role of betatrophin/angiopoietin-like protein 8 and irisin has been poorly investigated thus far. The aim of this study is to measure betatrophin and irisin serum levels in HCC, cirrhotic patients and controls, assess their relationship with cancer
Pazgan-Simon, Monika +8 more
openaire +4 more sources