Insulin upregulates betatrophin expression via PI3K/Akt pathway
Scientific Reports, 2017 Betatrophin is regarded as a liver-produced hormone induced by insulin resistance (IR). However, it remains largely unknown how IR regulates betatrophin expression. To study whether IR could regulate betatrophin expression and the corresponding molecular
Puhan Lu +12 more
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The association of the betatrophin level with metabolic and inflammatory parameters in infertile women with polycystic ovary syndrome: A case-control study [PDF]
International Journal of Reproductive BioMedicine, 2022 Background: Betatrophin may be associated with metabolic diseases. Objective: To investigate the betatrophin level and its association with metabolic and inflammatory parameters in infertile women with polycystic ovary syndrome (PCOS) and other infertile
Fatemeh Keikha +5 more
doaj +2 more sources
Associations of Betatrophin/ANGPTL8 with Septic Dyslipidemia in Human Peritonitis: An Explorative Analysis [PDF]
Biomedicines, 2022 Sepsis is defined by life-threatening organ dysfunction mediated by the host’s response to infection. This can result in septic dyslipidemia, which is involved in the neutralization of pathogen-related lipids.
Paul Horn +11 more
doaj +2 more sources
Decreased serum betatrophin may correlate with the improvement of obstructive sleep apnea after Roux-en-Y Gastric Bypass surgery [PDF]
Scientific Reports, 2021 Obesity is strongly correlated with obstructive sleep apnea (OSA), and bariatric surgery can effectively treat obesity and alleviate OSA. However, the contributing factors are still unclear.
Zhiyuan Song +9 more
doaj +2 more sources
Plasma and aqueous levels of subfatin, preptin and betatrophin in patients with diabetic retinopathy [PDF]
BMC Ophthalmology, 2023 Aim To examine subfatin, preptin and betatrophin levels in plasma and aqueous in patients with diabetes mellitus (DM) (with and without retinopathy). Material and method Sixty patients, who were similar in terms of age and gender, and were scheduled for ...
Sabiha Güngör Kobat +6 more
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Adipose Insulin Resistance and Circulating Betatrophin Levels in Women with PCOS [PDF]
BioMed Research International, 2020 The role of IR and metabolic disorders has become a crucial topic of study in the pathogenesis of PCOS. Adipose tissue is an important target organ of insulin, and adipose IR plays an important role in the occurrence and development of PCOS. This study seeks to investigate the role of adipose IR in the development of PCOS and to examine its ...
Yirui He +5 more
openaire +3 more sources
Betatrophin for diagnosis and prognosis of mothers with gestational diabetes mellitus [PDF]
Journal of International Medical Research, 2019 Objectives Betatrophin is a widely used diagnostic marker for type 2 diabetes mellitus (DM), but its clinical utility in diagnosing gestational DM (GDM) is unclear.
Ruirong Pan +7 more
doaj +3 more sources
Residual beta-cell function in children with type 1 diabetes after a partial remission phase – a possible relation between C-peptide and betatrophin [PDF]
Frontiers in EndocrinologyIntroductionMaintaining endogenous insulin secretion in type 1 diabetes (T1D) long after its onset, and thus the need for early diagnosis and searching for factors preserving the secretory function of β-cells, has become an important goal of current ...
Emilia Odyjewska +4 more
doaj +2 more sources
Betatrophin association with serum triglyceride levels in obstructive sleep apnea patients
Annals of Thoracic Medicine, 2019 BACKGROUND: Obstructive sleep apnea (OSA) is a common sleep problem, in which patients are at increased risk for metabolic and cardiovascular problems, including metabolic syndrome, diabetes mellitus (DM), and dyslipidemia. Betatrophin is a novel protein
Bunyamin Sertogullarindan +5 more
doaj +2 more sources
Circulating betatrophin/ANGPTL8 levels correlate with body fat distribution in individuals with normal glucose tolerance but not those with glucose disorders [PDF]
BMC Endocrine Disorders, 2020 Background The relationship between betatrophin/ANGPTL8 and obesity has been investigated using body mass index (BMI); however, since BMI reflects overall adiposity rather than body fat distribution, it remains unclear whether fat deposition in different
Jing Zheng +5 more
doaj +2 more sources