Alterations in serum concentrations of visfatin and betatrophin in dogs with hypothyroidism [PDF]
Journal of Veterinary Internal Medicine, 2023 Background Hypothyroidism in dogs is associated with obesity and altered lipid and carbohydrate metabolism. The adipokines, visfatin, and betatrophin, affect glucose tolerance. Betatrophin is involved in lipid regulation.
Michal Mazaki‐Tovi +2 more
doaj +5 more sources
Renal function is independently associated with circulating betatrophin. [PDF]
PLoS ONE, 2017 ObjectiveBetatrophin has been identified as a marker linking liver with beta cell function and lipid metabolism in murine models. Until now, the regulation of circulating betatrophin in humans is not entirely clear.
Lukas Maurer +9 more
doaj +6 more sources
Increased Maternal and Cord Blood Betatrophin in Gestational Diabetes. [PDF]
PLoS ONE, 2015 The aim of the study was to compare maternal and cord blood levels of betatrophin--a new peptide potentially controlling beta cell growth--as well as in its mRNA expression in subcutaneous adipose tissue, visceral adipose tissue and placental tissue ...
Natalia Wawrusiewicz-Kurylonek +12 more
doaj +6 more sources
Increased Circulating Betatrophin Concentrations in Patients with Type 2 Diabetes [PDF]
International Journal of Endocrinology, 2014 Betatrophin has recently been described as a key hormone to stimulate beta-cell mass expansion in response to insulin resistance and obesity in mice. The finding has generated an interest in the development of antidiabetic drugs with betatrophin as the ...
Daniel Espes +2 more
doaj +8 more sources
Irisin and betatrophin responses to 9 h of passive heat exposure: Influence of age, hypertension, and type 2 diabetes [PDF]
Physiological ReportsAge‐ and disease‐related metabolic responses to prolonged passive heat exposure are poorly understood. We evaluated serum irisin and betatrophin responses to 9 h of passive heat exposure (40°C, 9% relative humidity) in 19 young adults (19–31 years) and ...
Joel M. Garrett +7 more
doaj +3 more sources
Moderate-Intensity Exercise and Musical Co-Treatment Decreased the Circulating Level of Betatrophin
International Journal of Endocrinology, 2020 Introduction. In general, the significant contribution of lack of physical activity is strongly correlated with lipid metabolism and metabolic disorder. Hitherto, betatrophin is a potential hormone that regulates the lipid profile in the body circulation-
Hendra Susanto +6 more
doaj +3 more sources
Associations of Betatrophin/ANGPTL8 with Septic Dyslipidemia in Human Peritonitis: An Explorative Analysis [PDF]
Biomedicines, 2022 Sepsis is defined by life-threatening organ dysfunction mediated by the host’s response to infection. This can result in septic dyslipidemia, which is involved in the neutralization of pathogen-related lipids.
Paul Horn +11 more
doaj +5 more sources
Betatrophin Levels Are Related to the Early Histological Findings in Nonalcoholic Fatty Liver Disease [PDF]
Metabolites, 2021 Betatrophin, a liver hormone, regulates glucose and lipid metabolism. We investigated the betatrophin levels in nonalcoholic fatty liver disease (NAFLD) and searched for any relationship with histological severity and metabolic parameters.
Alper Sonmez +11 more
doaj +5 more sources
Betatrophin—Promises Fading and Lessons Learned [PDF]
Cell Metabolism, 2014 The discovery of a potent mitogen for insulin-producing pancreatic β cells, optimistically termed “betatrophin,” excited researchers and laypeople alike, promising a new therapeutic approach to diabetes.
Kaestner, Klaus H.
core +4 more sources
Endocrinology Research and PracticeObjective: Betatrophin is a hepatokine that modulates hepatic glucose and lipid metabolism and contributes to non-alcoholic fatty liver disease (NAFLD) pathogenesis.
Feyza Sarışık +7 more
doaj +4 more sources