Betatrophin and Insulin Resistance [PDF]
Metabolites, 2022 Betatrophin (angiopoietin-like protein 8 (ANGPTL8)) is a hormone that was recently discovered in the human liver. Multiple homologous sequences have been detected in mammalian liver, white adipose, and brown adipose tissues.
Qi Guo, Shicheng Cao, Xiaohong Wang
doaj +7 more sources
Alterations in serum concentrations of visfatin and betatrophin in dogs with hypothyroidism [PDF]
Journal of Veterinary Internal Medicine, 2023 Background Hypothyroidism in dogs is associated with obesity and altered lipid and carbohydrate metabolism. The adipokines, visfatin, and betatrophin, affect glucose tolerance. Betatrophin is involved in lipid regulation.
Michal Mazaki‐Tovi +2 more
doaj +5 more sources
Renal function is independently associated with circulating betatrophin. [PDF]
PLoS ONE, 2017 ObjectiveBetatrophin has been identified as a marker linking liver with beta cell function and lipid metabolism in murine models. Until now, the regulation of circulating betatrophin in humans is not entirely clear.
Lukas Maurer +9 more
doaj +6 more sources
Increased Maternal and Cord Blood Betatrophin in Gestational Diabetes. [PDF]
PLoS ONE, 2015 The aim of the study was to compare maternal and cord blood levels of betatrophin--a new peptide potentially controlling beta cell growth--as well as in its mRNA expression in subcutaneous adipose tissue, visceral adipose tissue and placental tissue ...
Natalia Wawrusiewicz-Kurylonek +12 more
doaj +6 more sources
Moderate-Intensity Exercise and Musical Co-Treatment Decreased the Circulating Level of Betatrophin
International Journal of Endocrinology, 2020 Introduction. In general, the significant contribution of lack of physical activity is strongly correlated with lipid metabolism and metabolic disorder. Hitherto, betatrophin is a potential hormone that regulates the lipid profile in the body circulation-
Hendra Susanto +6 more
doaj +3 more sources
Betatrophin Levels Are Related to the Early Histological Findings in Nonalcoholic Fatty Liver Disease [PDF]
Metabolites, 2021 Betatrophin, a liver hormone, regulates glucose and lipid metabolism. We investigated the betatrophin levels in nonalcoholic fatty liver disease (NAFLD) and searched for any relationship with histological severity and metabolic parameters.
Alper Sonmez +11 more
doaj +5 more sources
Associations of Betatrophin/ANGPTL8 with Septic Dyslipidemia in Human Peritonitis: An Explorative Analysis [PDF]
Biomedicines, 2022 Sepsis is defined by life-threatening organ dysfunction mediated by the host’s response to infection. This can result in septic dyslipidemia, which is involved in the neutralization of pathogen-related lipids.
Paul Horn +11 more
doaj +2 more sources
The association of the betatrophin level with metabolic and inflammatory parameters in infertile women with polycystic ovary syndrome: A case-control study [PDF]
International Journal of Reproductive BioMedicine, 2022 Background: Betatrophin may be associated with metabolic diseases. Objective: To investigate the betatrophin level and its association with metabolic and inflammatory parameters in infertile women with polycystic ovary syndrome (PCOS) and other infertile
Fatemeh Keikha +5 more
doaj +2 more sources
Insulin upregulates betatrophin expression via PI3K/Akt pathway
Scientific Reports, 2017 Betatrophin is regarded as a liver-produced hormone induced by insulin resistance (IR). However, it remains largely unknown how IR regulates betatrophin expression. To study whether IR could regulate betatrophin expression and the corresponding molecular
Puhan Lu +12 more
doaj +2 more sources
Adiponectin Intervention to Regulate Betatrophin Expression, Attenuate Insulin Resistance and Enhance Glucose Metabolism in Mice and Its Response to Exercise. [PDF]
Int J Mol Sci, 2022 Aims: Adiponectin stimulates mitochondrial biogenesis through peroxisome proliferator-activated receptor-coactivator1α (PGC-1α), a major regulator of mitochondrial biogenesis, and its effect on the genesis of insulin resistance is organ ...
Guo Q, Cao S, Wang X.
europepmc +2 more sources