Renal function is independently associated with circulating betatrophin. [PDF]
PLoS ONE, 2017 ObjectiveBetatrophin has been identified as a marker linking liver with beta cell function and lipid metabolism in murine models. Until now, the regulation of circulating betatrophin in humans is not entirely clear.
Lukas Maurer +9 more
doaj +8 more sources
Maternal and cord blood betatrophin (angiopoietin-like protein 8) in pregnant women with gestational diabetes and normoglycemic controls: A systematic review, meta-analysis, and meta-regression [PDF]
Diabetes/Metabolism Research and Reviews, Volume 39, Issue 4, May 2023., 2023 Aims: This systematic review and meta-analysis examined maternal and cord blood betatrophin levels in pregnant women with gestational diabetes mellitus (GDM) and normoglycemic controls.
López-Baena, María T. +5 more
core +2 more sources
Adipose Insulin Resistance and Circulating Betatrophin Levels in Women with PCOS [PDF]
BioMed Research International, 2020 The role of IR and metabolic disorders has become a crucial topic of study in the pathogenesis of PCOS. Adipose tissue is an important target organ of insulin, and adipose IR plays an important role in the occurrence and development of PCOS. This study seeks to investigate the role of adipose IR in the development of PCOS and to examine its ...
Yirui He +5 more
openaire +3 more sources
Moderate-Intensity Exercise and Musical Co-Treatment Decreased the Circulating Level of Betatrophin
International Journal of Endocrinology, 2020 Introduction. In general, the significant contribution of lack of physical activity is strongly correlated with lipid metabolism and metabolic disorder. Hitherto, betatrophin is a potential hormone that regulates the lipid profile in the body circulation-
Hendra Susanto +6 more
doaj +2 more sources
Increased Maternal and Cord Blood Betatrophin in Gestational Diabetes. [PDF]
PLoS ONE, 2015 The aim of the study was to compare maternal and cord blood levels of betatrophin--a new peptide potentially controlling beta cell growth--as well as in its mRNA expression in subcutaneous adipose tissue, visceral adipose tissue and placental tissue ...
Natalia Wawrusiewicz-Kurylonek +12 more
doaj +5 more sources
Insulin upregulates betatrophin expression via PI3K/Akt pathway [PDF]
Scientific Reports, 2017 Betatrophin is regarded as a liver-produced hormone induced by insulin resistance (IR). However, it remains largely unknown how IR regulates betatrophin expression. To study whether IR could regulate betatrophin expression and the corresponding molecular
Puhan Lu +12 more
doaj +3 more sources
Circulating betatrophin/ANGPTL8 levels correlate with body fat distribution in individuals with normal glucose tolerance but not those with glucose disorders [PDF]
BMC Endocrine Disorders, 2020 Background The relationship between betatrophin/ANGPTL8 and obesity has been investigated using body mass index (BMI); however, since BMI reflects overall adiposity rather than body fat distribution, it remains unclear whether fat deposition in different
Jing Zheng +5 more
doaj +2 more sources
Circulating fibroblast growth factor-21, Omentin-1, and betatrophin and their association with metabolic parameters in Saudi adolescents post 12-month lifestyle change program [PDF]
BMC PediatricsBackground Fibroblast growth factor-21 (FGF21) and omentin-1 have been recognized as potent antidiabetic agents with potential hepatoprotective activity.
Mona M. Alenazi +5 more
doaj +2 more sources
Betatrophin Acts as a Diagnostic Biomarker in Type 2 Diabetes Mellitus and Is Negatively Associated with HDL-Cholesterol [PDF]
International Journal of Endocrinology, 2015 Objective. By assessing its circulating concentrations in type 2 diabetes mellitus (T2DM) patients, we aimed to explore the associations of betatrophin with various metabolic parameters and evaluate its diagnostic value in T2DM. Methods.
Min Yi +5 more
doaj +3 more sources
Increased Circulating Betatrophin Concentrations in Patients with Type 2 Diabetes [PDF]
International Journal of Endocrinology, 2014 Betatrophin has recently been described as a key hormone to stimulate beta-cell mass expansion in response to insulin resistance and obesity in mice. The finding has generated an interest in the development of antidiabetic drugs with betatrophin as the ...
Daniel Espes +2 more
doaj +5 more sources