Results 61 to 70 of about 770 (178)

Correlation of serum betatrophin levels with disease severity and the emergence of insulin resistance in cirrhotic patients

open access: yesEgyptian Liver Journal, 2020
Background Insulin resistance (IR) is frequently associated with chronic liver disease. There has been an increased interest in betatrophin protein and its involvement in the compensatory response to IR.
Mohamed Magdy Salama   +3 more
doaj   +1 more source

High Serum Asprosin Levels Are Associated with Presence of Metabolic Syndrome

open access: yesInternational Journal of Endocrinology, Volume 2021, Issue 1, 2021., 2021
Objective. Asprosin, a new adipocytokine, has reportedly been associated with glucose release, dyslipidemia, and insulin resistance (IR). However, the relationship of asprosin with metabolic syndrome (MetS) remains unknown. This study aimed to investigate serum asprosin levels in MetS as well as their association with various metabolic parameters in ...
Tao Hong   +11 more
wiley   +1 more source

Mesenchymal Stem Cells: An Excellent Candidate for the Treatment of Diabetes Mellitus

open access: yesInternational Journal of Endocrinology, Volume 2021, Issue 1, 2021., 2021
Mesenchymal stem cells (MSCs) are adult stem cells (ASCs) known for repairing damaged cells, exerting anti‐inflammatory responses and producing immunoregulatory effects that can be significantly induced into insulin‐producing cells (IPCs), providing an inexhaustible supply of functional β cells for cell replacement therapy and disease modeling for ...
Qiulan Huang   +3 more
wiley   +1 more source

Betatrophin Levels were Increased in Pregnant Women with or without Gestational Diabetes Mellitus and Associated with Beta Cell Function [PDF]

open access: yesRevista Brasileira de Ginecologia e Obstetrícia, 2016
Purpose betatrophin has been reported to boost β cell expansion in insulin resistant states. Pregnancy is a well-recognized physiological state of insulin resistance.
Yun Huang   +5 more
doaj   +1 more source

Betting on betatrophin [PDF]

open access: yesScience-Business eXchange, 2013
Researchers at Harvard have discovered a hormone that promotes pancreatic islet β cell proliferation in mice. Partner companies Evotec and Johnson & Johnson have rights to the molecule and plan to turn it into a preclinical type 2 diabetes candidate this year.
openaire   +1 more source

Betatrophin [PDF]

open access: yesIslets, 2014
Regenerative therapy in diabetes with the capacity to reconstitute a functional β-cell mass sufficient for glycemic control holds the promise to effectively prevent the development of devastating late complications due to the unique ability of the β-cell to sense and regulate blood-glucose levels.
Ahnfelt-Rønne, Jonas, Madsen, Ole D
openaire   +1 more source

Evaluation of the Circulating Betatrophin Concentration and its Possible Correlations Among Diabetic Patients with Dyslipidemia

open access: yesEndocrinology Research and Practice, 2019
Objective: The circulating betatrophin levels in diabetic patients, treated with insulin or with oral hypoglycemic agents, were measured. The correlation between betatrophin levels and the glucose/lipid variables was also analyzed. Material and Methods:
Rasha M. HUSSEIN
doaj   +1 more source

Relationship between betatrophin levels and metabolic parameters in patients with polycystic ovary syndrome [PDF]

open access: yes, 2016
To evaluate the status of serum betatrophin levels and potential relations between metabolic parameters and betatrophin levels in patients with polycystic ovary syndrome. We included patients newly diagnosed with PCOS in our study.
Aylanc, N.   +6 more
core   +2 more sources

Decrease in fasting insulin secretory function correlates with significant liver fibrosis in Japanese non‐alcoholic fatty liver disease patients

open access: yesJGH Open, Volume 4, Issue 5, Page 929-936, October 2020., 2020
Japanese patients with NAFLD have significant fibrosis with reduced insulin secretion. These patients also tended to be significantly non‐obese. Abstract Background and Aim Non‐alcoholic fatty liver disease (NAFLD) is typically associated with metabolic syndrome and diabetes, and insulin resistance is involved in its pathogenesis.
Norimasa Araki   +11 more
wiley   +1 more source

Circulating Betatrophin Correlates with Triglycerides and Postprandial Glucose among Different Glucose Tolerance Statuses--A Case-Control Study.

open access: yesPLoS ONE, 2015
PurposePrevious researches of betatrophin on glucose and lipids metabolism under insulin-resistant condition have reached controversial conclusions. To further identify the possible impact of betatrophin, we measured the circulating betatrophin levels in
Ting Gao   +8 more
doaj   +1 more source

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