Results 151 to 160 of about 12,439 (211)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

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Biochemistry of Animal Virus Replication

New England Journal of Medicine, 1967
RECENT reviews which have appeared in this journal1 , 2 have pointed out the remarkable progress in the general areas of biochemical genetics, the biochemistry of proteins and nucleic acids and the understanding of the synthesis and function of these vital biologic macromolecules. The central facts, that ribonucleic acid (RNA) molecules are transcribed
openaire   +3 more sources

Transgene-mediated modifications to animal biochemistry

Trends in Biotechnology, 2000
The application of gene-transfer technology to domestic animals provides a way for the introduction of genes encoding biochemical pathways that are currently nonfunctional in these animals. This might provide a mechanism for increasing the availability of specific substrates that currently limit certain production characteristics, such as the ...
openaire   +2 more sources

Clinical Biochemistry of Domestic Animals

JAMA, 1964
For the teacher in veterinary clinical medicine or clinical pathology, this book is a most welcome addition to his armamentarium of teaching aids. It will help bridge the gap between basic and clinical sciences for the student in veterinary medicine. In addition, it should prove of value to the veterinary clinician in the interpretation of laboratory ...
openaire   +2 more sources

Comparative biochemistry of cytochrome c oxidase in animals

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2018
Cytochrome c oxidase (COX), the terminal enzyme of the electron transport system, is central to aerobic metabolism of animals. Many aspects of its structure and function are highly conserved, yet, paradoxically, it is also an important model for studying the evolution of the metabolic phenotype.
A G, Little, G, Lau, K E, Mathers, S C, Leary, C D, Moyes   +4 more
openaire   +2 more sources

Comparative biochemistry of acid proteinase from animal origins

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1986
Acid proteinases from 17 tissues of 12 animal species were compared with respect to molecular weight, inhibition by pepstatin and activation by tripolyphosphate. Gel filtration of acid proteinases from protochordates and vertebrates showed a common elution profile and three peaks with mol.
T, Ikeda, S, Watabe, N, Yago, S, Horiuchi   +3 more
openaire   +2 more sources

Micropet imaging: in vivo biochemistry in small animals

Journal of Neural Transmission, 2005
Significant technological advancements required for imaging physiological function in small animals have been achieved in the last few years. Dedicated small animals PET scanners are now achieving resolutions that approach the one obtainable by autoradiographic methods, while still maintaining enough detection sensitivity to reliably measure ...
V, Sossi, T J, Ruth
openaire   +2 more sources