Results 131 to 140 of about 2,222,991 (278)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Department of Chemistry and Biochemistry Seminar Schedule 2006 Fall

open access: yes, 2006
University of Minnesota Duluth. Department of Chemistry and Biochemistry. (2006). Department of Chemistry and Biochemistry Seminar Schedule 2006 Fall.
University of Minnesota Duluth. Department of Chemistry and Biochemistry
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Department of Chemistry and Biochemistry Seminar Schedule 2007 Fall

open access: yes, 2007
University of Minnesota Duluth. Department of Chemistry and Biochemistry. (2007). Department of Chemistry and Biochemistry Seminar Schedule 2007 Fall.
University of Minnesota Duluth. Department of Chemistry and Biochemistry
core  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Kansas Pet Animal Act: Policy and Procedures Field Manual, 2009

open access: yes, 2009
January 1, 2009The Kansas Pet Animal Act requires licensing and inspection of all dog and cat breeders who produce, offer or sell three or more litters during the state fiscal year, pounds and shelters, pet shops, research facilities, distributors, out ...
Kansas Animal Health.
core  

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